<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23626

Description Mediator of RNA polymerase II transcription subunit 33A isoform A
SequenceMELALALEWDDQVREGVLKKLKLWQQRNNKPPTAWVTELVEHFNTLGIALPCPELGELLVSQICFDNNHPLIWKFIHHALSSRLLFPLQILSLLSSNVLRHRHSHPHAFALFLPLLAQHAFSFLPTLSNNLKMVNSVDAVMRFSETYKIRDLELGHVFVLFFYDIVVALIDCVLIDWGFQVTFSEKSRLVTGGGGGDDEEDYMEIDRNMTTMTQSFEKSEQIRKRNSFTALEVLERLTESRKATILLQSVLLNMPEKFNCLQQRLQFLESLELASSELKSVNQVLTKVSASIRGVSRFDYCLRKHQLVGMLKASLRCNYRFCQSPCWVPFDIYMENAMDSRQIPTKSAIDVLTEAIKTLQILNQASWQETFLALWLSALRLVQRERDPPEGPIPHLVARLCVLLCIVPLAIANVLRDDSEHNSSSVQVSMESEYRHEMKSGSSMKLGLISSVQVLGHFSGLLCPPTLVIDAANQAARKAASFIYNTMNGKGESGTGIHANTNTKAGGNLRHLIVEACIARNLMDTSVYFWPGYVSTSVLSLSDSSPLEKSPWSIFMEGTPLNNTLINSLTVTPASSLVEIEKLYYIALNGSDVERPAAAKILCGASLSHGWYIQEHVVHHVVKLLASPVPPSHSGSQSPLVNNMPMLCAVLRGTSSIDTIHILSLYGVVPAVAASLLPLCETFGSIKPTSNSTGDESSSTSTSTSTYMTFSLAFLFLIRLWKFCRPPLDLCITELGVAVGGLEYILSLHNNRAMFSQDKLKSNPSLSDSASVKPVYIDSFPKLRALYCQYKSCVASALSGISTGNSIHQTANMILSMIYQKITKGGISSSNSSSPTTASSNACSSLMNSGEDNFQRPLLPAWEVLEALPFVLESILTACVHGRISSRELTTGLRDLVDFLPASLAAIIDYFSSEVTRGVWKLVPMNGTDWPSPAALIQSIESEIKAILTHVGVEVPNRSSGGSPVMLPLPMAALVSLSITFKLDKSQEYMHAITGAALENCASGCPWPSMPVIGSLWAQKVRRWHNFIVVSGSRSVFRHSNECVAQLLRSCFTSFLGTLCVSTSKLTAECNVNGLLGSTITAPGPYPFVAPGFLFLRSCRNIHNVQYVNDIIVGLVTEYSNELAGRRMGASSRHIKSNEVSLSLSAQSAKEVATLGASLLCAAGGILLVQELYKETIPTWLLSSRDVKQNNDSVGSYILEGYAMAYLLILSGSIIWGVGTKLPSGTFNRRKRTIEVHLDFLAEVMEKKISLSCNPITWKTYVCCLVGLMVSLAPAWVQEVKVDTLRKLARGLSRWNEHELALSLLHRGGTAAMGALAELVNVIESEHMLPCS
Length1332
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.08
Grand average of hydropathy0.128
Instability index46.80
Isoelectric point7.35
Molecular weight146464.67
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23626
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     276.23|      75|      77|    1002|    1078|       2
---------------------------------------------------------------------------
 1002- 1070 (105.18/68.25)	...........ASGcPWPSM.PVIGSLWAQKVRRWHN..FI..VVSGSRSVFRHSNECVAQ.LLRSCFTSFLGTLCVSTSkLTAEC
 1071- 1148 (97.41/54.65)	NVNGLLGStitAPG.PYPFVaP..GFLFLRSCRNIHNvqYVndIIVG..LVTEYSNELAGR.RMGAS.SRHIKSNEVSLS.LSAQS
 1151- 1213 (73.64/39.25)	EVATLGASllcAAG....GI.LLVQELYKETIPTW........LLS.SRDV.KQNNDSVGSyILEGYAMAYLLILSGS........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.39|      16|      21|     283|     298|       4
---------------------------------------------------------------------------
  283-  298 (26.18/15.40)	QVLTKVSASIRGVSRF
  306-  321 (29.21/17.99)	QLVGMLKASLRCNYRF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.74|      18|     149|     118|     135|       5
---------------------------------------------------------------------------
  118-  135 (33.37/18.83)	QHAFSFLPTL...SNNLKMVN
  262-  282 (25.37/12.65)	QQRLQFLESLelaSSELKSVN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.05|      11|      23|     800|     810|      10
---------------------------------------------------------------------------
  800-  810 (20.97/12.20)	GISTGNSIHQT
  826-  836 (20.09/11.36)	GISSSNSSSPT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.96|      42|     371|       9|      51|      11
---------------------------------------------------------------------------
    9-   51 (69.73/58.34)	WDDQVREGVLKKLKLwQQRNNKPPTAWVTELVEHFNTLGIALP
  367-  408 (76.23/56.91)	WQETFLALWLSALRL.VQRERDPPEGPIPHLVARLCVLLCIVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.44|      17|      23|     876|     892|      12
---------------------------------------------------------------------------
  876-  892 (30.28/20.34)	LTACVHGRIS..SRELTTG
  900-  918 (23.16/13.67)	LPASLAAIIDyfSSEVTRG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.15|      17|     325|     629|     646|      14
---------------------------------------------------------------------------
  629-  646 (30.24/19.99)	VPPSHSGSqSPLVNNMPM
  955-  971 (33.91/18.08)	VPNRSSGG.SPVMLPLPM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23626 with Med33 domain of Kingdom Viridiplantae
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