<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23612

Description Mediator of RNA polymerase II transcription subunit 33A
SequenceMGEVFQNMSEEEEEEEGSVMDGVMEVTKWAQEKKTDPLIWSIQVSSALNSGGVSLPSVELAQRLVSHICFENHVPITWKFLEKAMSVRLLPPLLVLSLLSARVVPQRRLHPSAYALYMDLLSRHAFSPHIHFPNYLKVMASIHHSLSLPPSNHHPHPGVVLVHFLFSIVSQLLQSSLDDQGFLQHSPDPYNNNDALHRKNTAMAIEIIARFLHHKLTSRILALVQRNMPAHWGPFLHQLQQLAANSTVLRSLKHVTPESLLPLDFNSTTGNGIKLLSSDWKTTPTLELNAVMADSCAVQSRHDSWSLLWLPIDLILEDAMDGNHVAEASAVEALTGLVKALQAVNGTAWHSAFLGLWIAALRLVQRERDPGEGPVPRLDTCLSMLLCITTLVVANLIEEEEGKLIEEAERSPANQRMDKQALGERHGALVTSLQLLGDYENLLTPPQSVIWGANQAAAKATLFVSGHSGYLEHTNVNDLPTNCSGNLRHLIVEACIARHLLDTSAYFWHGYVSTPFNQLPHSIPNHLPSWSSLMKGSPLTPPLVNVLVATPASSLAEIEKIFEFAINGSDEEKISAATILCGASLVRGWNVQEHIVFFIINMLSPPVPPKYSGTESYLISHAPFLNVFLVGISSVDSVQIFSLHGVVPLLAAVLMPICEAFGSSVPNVSWTAVTGEKLTCHAVFSNAFILLLRLWRFDRPPVEHVMGGAATPALGSQLGPEYLLLVRNCMLAAFGKSPRDRVRSRRFSKMIRFSLEPLFMDSFPKLNIWYRQHQECIASICNTLAPGGPVSQIVEALLTMMCKKINRSAQSLTPTTSGSSNSSLPSLDDALMKLKVPAWDILEATPFVLDAALTACAHGSLSPRELATGLKDLADFLPATLGTIVSYLSSEVTRCIWKPAFMNGTDWPSPAANLSIVEQQIKKILAATGVDVPSLAIDGNAPATLPLPLAAFLSLTITYKLDKSCERFVILAGPSLIALSSGCPWPCMPIVGALWAQKVKRWSDFFVFSASATVFHHSRDAVVQLLRSCFASTLGLGSACIYNNGGVGTLLGHGFGSHYSGGFTPVAPGFLYLRVYRSIRDVMFLTDEIVSLLMLSVRDIANGGLPKGEVEKLKKTKYGIRYGQVSLAASMTRVKHAALLGASILWISGGSGLVQSLITETLPSWFLSAQGLEQEGGESGVVVAMLRGYALACFAVLGGTFAWGIDSLSPASKRRPKVLEIHLEFLANALDRKISLRCDCATWRAYVSGVMSLMVSCTPLWIQELDVGILKRMSSGLRQLNEEDLALRLLEIRGTSVMGEAAEMICQTRL
Length1310
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.07
Grand average of hydropathy0.190
Instability index47.97
Isoelectric point6.57
Molecular weight143009.08
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23612
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     187.14|      60|     389|       4|     150|       1
---------------------------------------------------------------------------
   84-  150 (97.29/72.04)	AMSVRLLPPLLVL...SLLSA.......RVVPQR...RLHPSAYALYMDllsrhAFSP.HIHFPNYLKVMASIHHSLSlpP
  713-  786 (89.85/52.76)	ALGSQLGPEYLLLvrnCMLAAfgksprdRVRSRRfskMIRFSLEPLFMD.....SFPKlNIWYRQHQECIASICNTLA..P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.58|      33|     359|     787|     846|       2
---------------------------------------------------------------------------
  787-  826 (45.46/64.34)	GGPVSQivEALLTMMckkinRSAQSLTPTTSGSSNSSLPS
  858-  890 (55.13/21.55)	HGSLSP..RELATGL.....KDLADFLPATLGTIVSYLSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.96|      18|      94|    1146|    1165|       3
---------------------------------------------------------------------------
  463-  480 (33.66/10.55)	FVSGHSGYLEHTNVNDLP
 1146- 1163 (32.30/14.02)	WISGGSGLVQSLITETLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     196.51|      63|     388|     231|     319|       6
---------------------------------------------------------------------------
  251-  318 (93.46/94.08)	SLKHVTP..ESLLpLDFNSTTGNGIKLLSsdWK..TTPTLELNAVMADSCAVQSRhdSWSLLWLPIDLILED
  642-  708 (103.05/52.05)	SLHGVVPllAAVL.MPICEAFGSSVPNVS..WTavTGEKLTCHAVFSNAFILLLR..LWRFDRPPVEHVMGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.70|      40|     386|       4|      43|       7
---------------------------------------------------------------------------
    4-   43 (70.45/51.02)	VFQNMSEEEEE...EEGSVMDGVMEVTKWAQEKKTDPLIWSIQ
  392-  434 (60.25/42.51)	VVANLIEEEEGkliEEAERSPANQRMDKQALGERHGALVTSLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.58|      14|     137|     221|     234|      11
---------------------------------------------------------------------------
  221-  234 (28.86/16.91)	LALVQRNMPAHWGP
  361-  374 (26.73/15.10)	LRLVQRERDPGEGP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23612 with Med33 domain of Kingdom Viridiplantae
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