<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23396

Description Mediator of RNA polymerase II transcription subunit 24-like protein
SequenceMQKSQCILCLLNLVISFKQRIGCYGNEEECITLCKSIVSLTLWIYSCVSHAFTVSVESKSFSQNQNQFNYQHHNHHHHSGMAGATGASVVALSPFVGQTNDFYLIIEKIADILNYISNSSFLKALFYVGKMEDPSTYSQLLTRVNEVESKITTASNLNAQFNKEVLETILGFMSAVEWNKCTPTVVASKQLQSTAIGSNNQLIYDSVFRSLNAVIAFDAVLNPVCEIDVCAEQIFLISKFNDISLSDLCCEIIRACFVGLVDSGGSGEDLKWAAFTFLKAPQLLVKLIQMKGEKSKGNLSNDLEVGLEKLLAYTPLLDLTDTKSNCDCLELFLKELCKTELLTENKKNRIMSLRQKETTGKAPLSRADQSQAGQGASLILRAEPTVTSILKTLDSDYSKNQDALLGVLCHMVPGKSFELILNAAAATGKLRSFTTKLIKFNEFNKQVTGEGGKASQTRALLFDITFLMLCHIAQNYGTEIVTANEETKDSFFATWCAQCLTEGGRYRNPDAILINCEQNKVDVLLNQFTSTDSEFKTSLVKWHEFCMNAPAAIKEILLAWEHEVITTDNVKLILDNVKSKMCCLPVVISAWLCSYINVLHHDERLKPINMVQQFMTPLVTDAANNNGSEQQSNSDFYKERSTLMAAIIKKMFYDLHPPYQTKTKGIISVISHGLTSKTPLLKIMETNFALAHDRSWLDVKTVHNMDTLLCVGGSNWFVDALVRHLLKFEHDNDLNRAVDMIFGLFHLDIEQCALSLLLNTLKSYLLNSAKQEQLCEPKISSLARLTVMTIFSALNELQNSKLGKQRSGRKKHHYLEDNPSDFDPFEADLKHSLSNSGSIPRPPKLPKSDTRYGSMTLLEETPFTFQQQQQGQQVSSPFLNEPLTKSIVELLRLLTVIITDSTVSPRTLFPLVFLEQLILCAKEDAHKILRFLPFQMIISLLKTFPETLTYEFLLSISNTETLKARKIVARALCQLKRAKKSGSNFMS
Length987
PositionTail
OrganismDinothrombium tinctorium
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Chelicerata> Arachnida> Acari> Acariformes> Trombidiformes> Prostigmata> Anystina> Parasitengona> Trombidioidea> Trombidiidae> Dinothrombium.
Aromaticity0.08
Grand average of hydropathy-0.059
Instability index37.91
Isoelectric point6.91
Molecular weight110591.44
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23396
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.55|      26|      62|     408|     435|       1
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  408-  435 (40.13/31.33)	LCHMVPGKSFELIlnAAAATGKLRSFTT
  469-  494 (45.42/28.98)	LCHIAQNYGTEIV..TANEETKDSFFAT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.65|      45|      65|     761|     807|       2
---------------------------------------------------------------------------
  761-  807 (68.28/52.28)	LKSYLLNSAKQEQlcEPKI.SSLARLTVMTIFSALN.ELQNSKLGKQRS
  829-  875 (70.36/46.54)	LKHSLSNSGSIPR..PPKLpKSDTRYGSMTLLEETPfTFQQQQQGQQVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.60|      18|      55|     446|     463|       3
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  446-  463 (30.39/20.83)	QVTGEGGKASQTRALLFD
  498-  515 (33.21/23.45)	QCLTEGGRYRNPDAILIN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.70|      14|      90|      56|      69|       5
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   56-   69 (26.89/18.88)	VESK.SFSQNQN.QFN
  147-  162 (16.80/ 8.76)	VESKiTTASNLNaQFN
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     197.48|      64|     127|     543|     611|       9
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  543-  611 (99.96/72.32)	HEFCMNAP.AAIKEILLAWEHEVITTDnVKLIlDNVKSKMCclpVVISAW....LCSYINVLHHDERL.KPINMV
  672-  741 (97.53/55.09)	HGLTSKTPlLKIMETNFALAHDRSWLD.VKTV.HNMDTLLC...VGGSNWfvdaLVRHLLKFEHDNDLnRAVDMI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23396 with Med24 domain of Kingdom Metazoa
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