<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23391

Description Mediator of RNA polymerase II transcription subunit 36a
SequenceMAAGLEEEVVEEVAEETVVGRGGGGRGRGGGRGGGRGGRGRGGGGMKGGNRVVIEPHRHDGVFVAKGKEDALVTKNLAIGESVYGEKRVSVQNEDGTKVEYRIWNPFRSKLAAAILGGVDNIWITPGSKVLYLGAASGTTVSHVSDIVGPNGVVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPAKYRMLVSMVDVIFSDVAQPDQARILALNASYFLKIGGHFVISIKANCIDSTVPAEAVFAQEVKKLQADQFKPSEQVTLEPFERDHACVVGGYRIPKKQKVPAS
Length291
PositionUnknown
OrganismCinnamomum micranthum f. kanehirae
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Magnoliidae> Laurales> Lauraceae> Cinnamomum.
Aromaticity0.06
Grand average of hydropathy-0.214
Instability index34.70
Isoelectric point9.22
Molecular weight31101.10
Publications
PubMed=30626928

Function

Annotated function
GO - Cellular Component
GO - Biological Function
methyltransferase activity	GO:0008168	IEA:UniProtKB-KW
RNA binding	GO:0003723	IEA:UniProtKB-KW
GO - Biological Process
methylation	GO:0032259	IEA:UniProtKB-KW
rRNA processing	GO:0006364	IEA:UniProtKB-KW

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP23391
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.55|      12|      17|      20|      32|       1
---------------------------------------------------------------------------
   20-   32 (22.53/11.76)	GRGGGGRgRGGGR
   40-   51 (27.02/10.45)	GRGGGGM.KGGNR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.66|      17|      17|     171|     187|       2
---------------------------------------------------------------------------
  171-  187 (29.90/18.79)	AKKR..TNVIPII.EDARHP
  188-  207 (19.76/10.48)	AKYRmlVSMVDVIfSDVAQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.52|      15|      17|     134|     148|       3
---------------------------------------------------------------------------
  134-  148 (25.26/17.66)	GAASGTTVSHVS..DIV
  152-  168 (21.26/13.77)	GVVYAVEFSHRSgrDLV
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP23391 with Med36 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AEETVVGRGGGGRGRGGGRGGGRGGRGRGGGGMKGGNRV
14
52

Molecular Recognition Features

MoRF SequenceStartStop
1) GYRIPKK
2) RGGGRGGGRGGRGRG
279
28
285
42