<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23386

Description U-box domain-containing protein 35 isoform X1
SequenceMEVPEVGEELVSIPPSVSTVAIAVNGKGNCKSALKWALEKFGPEGRYFFKLLHVRPKITMVPTEMGNYLPISNVRDDVASAYRKEIEWRTNTMLLPYKKMCSQKKVEAEAVVIEAEDVPEAISLEIAKFSISTLVIGGSSRSLLARKFRGHDVSSRISGCIPSFCTVYIISKGRLSSVRTSTSDTDERTLDERSDSNVSTKSSSSSTSSPQTEWTDTGSVSNHSFYHSSSLPDQRYQALLTINQAIVNKRPSPFDTYHSRSLSLNTEEDAIGSISNCSGIKDGVSIACSSRSYQTDNKSWISDLVSMSDIMTDLSLSGQVDVDFELEKLRIELRHAQGMYEMAQNETNDASRHLNELSRRRLEEAIKLKEIRLREEQARKLARQEKEKIEGMKREAELVRECAEREASQRKEAEVKATRDAEEIQKLEKALTCSNQQYKKFTWEEIVSATSSFSEALKIGMGGYGMVYKCTLHHTTVAVKVLHSNEEQSNKQFEQELEILSTIRHPHLLLLLGACLDHGCLVYEYMENGSLDDRLFRKNNTPPIPWFVRYRIAWEIATALVFLHNAEPKPIVHRDLKPANILLDRNFVSKIGDVGISTLLPTASSSMSTMAKDTAPAGTFCYIDPEYQRTGKVSPKSDVYAFGMVILQLLTTKPPLALTETVETALEEGRLVDILDSKAGKWPIEETQELAALGLRCAELRRRDRPELKDEVLPMLERLKEIAARAQELVPVVPSVPPNHFICPILQDVMEDPCVAADGYTYERRAIDQLLSTNDKSPMTNAPLPHKNLIPNFNLLSAIMEWKSKHQ
Length807
PositionTail
OrganismCinnamomum micranthum f. kanehirae
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Magnoliidae> Laurales> Lauraceae> Cinnamomum.
Aromaticity0.06
Grand average of hydropathy-0.392
Instability index46.73
Isoelectric point6.01
Molecular weight90598.20
Publications
PubMed=30626928

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23386
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.02|      22|      24|     366|     387|       1
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  366-  387 (34.28/22.76)	IKL.KEIRLREEQARKLARQEKE
  392-  412 (31.93/20.69)	MK..REAELVRECAEREASQRKE
  425-  445 (22.81/12.69)	QKLeKALTCSNQQYKKFTWEE..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.69|      20|      24|     188|     211|       2
---------------------------------------------------------------------------
  192-  211 (33.73/23.35)	ERSDS.NVSTKSSSSSTSSPQ
  213-  233 (33.96/14.13)	EWTDTgSVSNHSFYHSSSLPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.58|      26|      28|     259|     286|       3
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  259-  286 (38.70/26.65)	SRslSLNTEEDA.IGSISNCSGIKDGVSI
  290-  316 (38.89/21.21)	SR..SYQTDNKSwISDLVSMSDIMTDLSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.44|      19|     303|     235|     253|       4
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  235-  253 (33.82/27.93)	RYQALLTINQAIV...NKRPSP
  549-  570 (29.61/23.38)	RYRIAWEIATALVflhNAEPKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     170.21|      45|     303|     317|     364|       5
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  317-  364 (68.27/53.23)	SGQVDV.DFELEKLRIElrHAQGMYeMAQNETNDASRHLNELSRR.RLEE
  634-  668 (54.38/32.71)	SPKSDV.............YAFGMV.ILQLLTTKPPLALTETVET.ALEE
  669-  707 (47.56/27.73)	GRLVDIlDSKAGKWPIE..ETQ........ELAALGLRCAELRRRdRPE.
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     232.01|      75|     722|       2|      89|       6
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    2-   89 (114.23/97.89)	EVPEVGEELV....SIPPS..VSTVAIAVNgKGNCKSALKWALEKfgpegRYFFKLLHVRPK..ITMVPTEMGNYLPISNVRDDVasayrkeIEWR
  721-  803 (117.78/71.68)	EIAARAQELVpvvpSVPPNhfICPILQDVM.EDPCVAADGYTYER.....RAIDQLLSTNDKspMTNAPLPHKNLIPNFNLLSAI.......MEWK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23386 with Med32 domain of Kingdom Viridiplantae
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