<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23376

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMAEKQLIVAVEGTAAMGPFWNAMLTEYLDKIISFDFQSNEVLFLSNLIILRCRSFLAQVLSLHWLCLMHMDLIVNKVFPITDAACLVQRSGWTRDMDVFLQWLAAIPFTGGGFSEVAIAEGIAEALMMFSVTSNGNQTQPSVDWQKHCILVAASNPYSLPTPVSHPSVQKMEQSDSAEVQSESRLSDAETVAKSFSQCCVSLSVISPKQLPKLRTIYSAGKRNPRATDPAVDNAKNPQFLVLISENFMEARAALTRPGITNLAANQSPLKLDTAPVPPISGSAPTSIPSGAKVSDPHLDTIPKQNKSHREQRALAFEVNGSMMNRQPIPAGNIPTATVKVEPSTVASMVPGPPFSHLASHGASQGVPSLQFSSPSPTSQEMITSGDSVQEFKPMVSGMPQPLRPAGPAAANVSILNNLSQAQARQVISSASLAGGSSMGLQTMGGMTMHMISSGMSSSALPAAQTVLSSGQSGINSITGSGAIVGPGQVTQNTGLGSFTSATSTMSGNSNHGMSPPLGNLQGAVSMAQSVSGMGQGNLTSGAQLGQSGVGINQNIMNSLGPSGMPSGAGTMIPTPGMSQPVQVGLPSLGVNNGSAASMTLPQHASGPMQSQSKYLKVWEGALSGQRQGQPVFICRLEGYRNASASETLAADWPATMQIVRLISQDHMNNKQYVGKADFLVFRALNHHGFLGQLQEKKLCAVIQLTSQTLLLSVSDKASRLIGMLFPGDMVVFKPQISSQQQQLQQQQLQQQQQQQQQQLQQQQLQQHQQQQPQQLPQQQMVGAGMNQTFVQGPGRSQIMSQGQVPSQGPPSMPGSGFLS
Length819
PositionUnknown
OrganismCinnamomum micranthum f. kanehirae
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Magnoliidae> Laurales> Lauraceae> Cinnamomum.
Aromaticity0.05
Grand average of hydropathy-0.159
Instability index54.32
Isoelectric point8.54
Molecular weight86801.92
Publications
PubMed=30626928

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23376
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.18|      15|      15|     739|     753|       1
---------------------------------------------------------------------------
  739-  753 (31.80/13.37)	QQQQLQQQQLQQQQQ
  755-  769 (32.38/13.74)	QQQQLQQQQLQQHQQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.80|      20|      25|     559|     582|       2
---------------------------------------------------------------------------
  563-  587 (32.60/16.67)	GMPSgagTMIPTPGMSQPV...QvgL....PS
  784-  810 (25.20/ 8.56)	GMNQ...TFVQGPGRSQIMsqgQ..VpsqgPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     331.22|      69|      72|     275|     343|       3
---------------------------------------------------------------------------
  153-  200 (61.86/26.17)	ASNPYSLPT..PVSHPSVQKM.EQSDSAEVQ.........SES.............RLSDAET.VAKSF.....SQCCV.................
  201-  280 (74.08/32.70)	...SLSVISPKQL..PKLRTIYSAGK..RNPRATDPA..VDNAknpqflvlisenfMEARAAL.TRPGItnlaaNQSPLKLDTA......PVPPIS
  281-  355 (113.80/53.94)	GSAPTSIPSGAKVSDPHLDTIPKQNKSHREQRALAFE..VNGS.............MMNRQPI.PAGNI.....PTATVKVEPStvasmvPGPPFS
  360-  419 (81.48/36.66)	HGASQGVPS.LQFSSPS.PT..SQEMITSGDSVQEFKpmVSG...............MP.QPLrPAG.......P.AAANV..S......ILNNLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      73.55|      16|      17|     518|     533|       4
---------------------------------------------------------------------------
  496-  513 (20.13/ 7.84)	GSFTSATStMsGNSNHGM
  518-  533 (28.70/14.79)	GNLQGAVS.M.AQSVSGM
  536-  551 (24.72/11.56)	GNLTSGAQ.L.GQSGVGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.55|      15|      15|     606|     620|       7
---------------------------------------------------------------------------
  606-  620 (28.94/19.78)	GPMQSQSKYLKVWEG
  624-  638 (27.60/18.45)	GQRQGQPVFICRLEG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23376 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GINQNIMNSLGPSGMPSGAGTMIPTPGMSQPVQVGLP
2) LTRPGITNLAANQSPLKLDTAPVPPISGSAPTSIPSGAKVSDPHLDTIPKQNKSHREQRALAFEVNGSMMNRQPIPAGNIPTATVKVEPSTVASMVPGPPFSHLASHGASQGVPSLQFSSPSPTSQEMITSGDSVQEFKPMVSGMPQPLRPAGPAAAN
3) QQQLQQQQLQQHQQQQPQQLPQQQMVGAGMNQTFVQGPGRSQIMSQGQVPSQGPPSMPGSGFLS
4) QVTQNTGLGSFTSATSTMSGNSNHGMSPPLGNLQGAVSM
550
254
756
488
586
411
819
526










Molecular Recognition Features






MoRF SequenceStartStop




NANANA