<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23363

Description RNA polymerase II holoenzyme cyclin-like subunit
SequenceMSANYWESTQRRFWQFTKDQLVTMRQKLEDDNAELVRMFPLPQQRHLNIYFNQQLIRLAKRLTIRQQSMATAQVYMKRFYSKVEIRRTNPYLVIATAIYLACKMEESPQHIRLIVTEARQMWGDLVAIDTSKLGECEFFMISEMRSQLIVHQPYRSISALRSELSLVEDEVQLARSVINDHYMTDLPLLYAPHIIALVAILLALVLRPNNSAPGQSSGSAAAAGLAAAQQALLRAQGQSSQTGFSDASAAEPKEKQQQARVSRVQRFAAWLVESNVEIASMVDATQEIISFYECYEQYNDKLTREQINRFVKARGLDK
Length318
PositionKinase
OrganismFusarium sp. AF-4
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Nectriaceae> Fusarium> Fusarium solani species complex> unclassified Fusarium solani species complex.
Aromaticity0.08
Grand average of hydropathy-0.266
Instability index63.98
Isoelectric point8.88
Molecular weight36458.41
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23363
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.42|      24|      27|     197|     221|       1
---------------------------------------------------------------------------
  197-  221 (36.92/29.85)	LVAILLALvLRP..NNSAPGQSSGSAA
  225-  250 (35.50/23.57)	LAAAQQAL.LRAqgQSSQTGFSDASAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.28|      18|      23|      64|      86|       2
---------------------------------------------------------------------------
   64-   86 (22.62/36.85)	IrqqsMATAqVYM..KRFYSKVEIR
   93-  112 (27.66/21.79)	V....IATA.IYLacKMEESPQHIR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.12|      19|      32|      10|      28|       3
---------------------------------------------------------------------------
   10-   28 (34.11/20.19)	QRRFWQFTKDQLVTMRQKL
   44-   62 (32.00/18.58)	QRHLNIYFNQQLIRLAKRL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23363 with CycC domain of Kingdom Fungi
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