<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23356

Description Uncharacterized protein
SequenceMAANYWESTQRKNWQFSKEQLASMRQKLEDEDQGLVQSFGLPQLPHLNIFFNQQINRLGKRLGVRQQAMATAQVYIKRFYTKVEIRRTNPFLVITTALYLACKMEECPQHIRLMNQEARSLWTDMQLFQDPSKIGECEFWLISEMSSNLIVHQPYRTLTGLQSSLGLTQDEMALSWSIINDHYMTDLPLLYPPHTVALMAILLAIVFRPSQNTTQAGAAAAAAAQAAAAAAGGGAAAGAAMAQPGMAGINAVTAALAQAQARQPPTPGGGGAVVGPPGGQQQQQAGAADGPAGGVSASQSAALSKEKNERYSKMHRFGLWLAESNIDIEAIVDCTQELISFYDFQEQYNDKLTREQIVRFIKARGLDKG
Length369
PositionKinase
OrganismCytospora leucostoma
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Diaporthales> Valsaceae> Cytospora.
Aromaticity0.08
Grand average of hydropathy-0.236
Instability index56.58
Isoelectric point7.01
Molecular weight40406.57
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP23356
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      90.41|      15|      15|     217|     231|       1
---------------------------------------------------------------------------
  217-  231 (23.45/ 9.32)	GAAAAAAA..QAAAAAA
  233-  247 (25.55/10.73)	GGAAAGAA..MAQPGMA
  252-  266 (22.66/ 8.80)	VTAALAQA..QARQPPT
  286-  302 (18.74/ 6.17)	GAADGPAGgvSASQSAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.91|      16|      25|     144|     161|       2
---------------------------------------------------------------------------
  144-  161 (24.78/22.58)	EMS.SNLIVHQPYrtLTGL
  171-  187 (27.12/17.37)	EMAlSWSIINDHY..MTDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.38|      12|      20|      55|      66|       3
---------------------------------------------------------------------------
   55-   66 (19.41/12.05)	INRLGKRLGVRQ
   76-   87 (17.97/10.71)	IKRFYTKVEIRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.36|      14|     195|     130|     143|       4
---------------------------------------------------------------------------
  130-  143 (27.84/21.50)	DPSKIGECEFWLIS
  327-  340 (22.52/16.03)	DIEAIVDCTQELIS
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP23356 with CycC domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AQAQARQPPTPGGGGAVVGPPGGQQQQQAGAADGPAGGVSASQSAALSKEK
257
307

Molecular Recognition Features

MoRF SequenceStartStop
NANANA