<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23355

Description Putative mediator of RNA polymerase II transcription subunit 24 isoform X1
SequenceMVLEPLSSSKAGTIRSLLIRAWRERWSDLQWGIHIKTVLPRAVSGDIYHLADYILQQALMGPLPNNLILSYLRHSLSSQIVSYGGVIESISKYDGLHKPHCVHALLDLMQSMMKSVSCRGKPEDCLVLATSIVGGVKWLIQVMGWSTQQLLDLRNAPELSANLSLAASILHEILNCTFLTCMLEIGRREEPGTWSTCMKKMTEVETLLAGAGTIIENKDILIKTVCQLRDIQPLDSIGSKHKFDSTSVPLCHAMHSLVMLEVITHTTRDAATFAHQLLLLQQLQGLTTMQLYLELLRSSFLGLSCPEHQAYQELKWVGFTFIKVPTILYTIHVMLNGENATGESEDLLTAVQRLAQLTILLDQVDSRINCNCLEYLLNELCNKTSLISERDAQEIITKRVKESNVLSNIQKNDAQGSHPGNPNLILRAQPTVTSILKTLSNKNQESVLPVMNLLISGKSRDLLLVAAAASGSLHIFAQKFVKFNEVSMDPQPGETSKMAINRALMFDISFLLLCHIAQLYGIDVVVSEKCETFVEQWMKENMPELGRVKAPLMTTRTDQNAVEDFIRQVNVTDLDLKYNMVPWSELCQVAAVAFREVVSAAQQGAVPIQRVKELLDRLRYHLCCLPICVATWLCSHVQVVDGEQAVQPLSFLNYLLTSFNDHDASVPTLENFKDRSTLMVQIVENMAQVMKGGAQPAVNNDSMNNSSSGKSLQKEESTNSLLSSQEPLSNLLRETWKQVFPGGVMLLGNGGGGFGDTGMQSVFKSDLARAVDLIYALLHQDVVGCTLSLLVHALPMYISGPCSADLLSEPRTHALAHLAVMMIISAWLAVQQPPVKPEPGSTMSMVMGATPGGPSNYRKRTYHDRILDDLESSLQAHSVELAIARGTPGHTLLTLTPPALLPNLVPLLSPPDAFTYAELLAITAPKPTCQSGLAKDFIGDFIGAQTPAQAAGARRAAAKLLCVQRNLALANESFTELTL
Length979
PositionTail
OrganismPenaeus vannamei (Whiteleg shrimp) (Litopenaeus vannamei)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Crustacea> Multicrustacea> Malacostraca> Eumalacostraca> Eucarida> Decapoda> Dendrobranchiata> Penaeoidea> Penaeidae> Penaeus.
Aromaticity0.06
Grand average of hydropathy0.077
Instability index43.94
Isoelectric point6.10
Molecular weight107619.60
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23355
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     356.19|     113|     287|     342|     457|       1
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   59-  134 (101.49/65.44)	..................................LMG...............PLPN..NLILSYLRHSLSSQI...VSYGGVIESISKYD..GLH..KPHCVHALLDLMQSMMKSVSCRGKpEDCL.VLATSIVG
  148-  240 (82.99/51.16)	QQLLDLRNAPELSANLSLAASILHEILNCTFLTCMLEigrreepgtwstcmkKMTEVETLLA..GAGTIIENKdilIKTVCQLRDIQPLDSIGSK........................................
  342-  457 (171.71/128.40)	GESEDLLTAVQRLAQLTILLDQVDSRINCNCLEYLLN...............ELCNKTSLISERDAQEIITKR...VKESNVLSNIQKNDAQGSHpgNPNLILRAQPTVTSILKTLSNKNQ.ESVLpVMNLLISG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.01|      35|     287|       3|      39|       2
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    3-   39 (53.97/38.63)	LEPLSSSKAGtIRSLLIRAWRE.RWSDLQWgIHIKTVL
  293-  328 (59.04/33.46)	LELLRSSFLG.LSCPEHQAYQElKWVGFTF.IKVPTIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     195.21|      60|     154|     686|     747|       6
---------------------------------------------------------------------------
  686-  747 (96.83/65.82)	MAQVMkgGAQPAVNNDSMNNSSSGKSLQ......KEESTNSLLSSQEPLSNLLRETWKQVFPGGVMLL
  843-  908 (98.38/60.91)	MSMVM..GATPGGPSNYRKRTYHDRILDdlesslQAHSVELAIARGTPGHTLLTLTPPALLPNLVPLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23355 with Med24 domain of Kingdom Metazoa
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