<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23308

Description Mediator of RNA polymerase II transcription subunit 33A isoform X2
SequenceMEVSTAIPLWDSVLELTKGAQEQGSDPLLWAIHLSSTLNSASISLPSADLAHVLVSHICWGNNVPMAWKYLEKALAFKIVPPMLVLALLSSRIMTSIDDVLHLSQVFGIQECEPGVLVVEFVFSIVWQLLEATLDDEGLLELTTERKSIWATRSQDMEIDYENSFDERRTENYDKLQKANTVMAIELIVQFLRQKLVSRLLYLARQNMPSHWGGFMQRLRLLGTNSSALRNSTISPEILLKSSSLYTPKSFGLECKPSPHQDSRAVIASASLTSSAGDCFGPSTSALWIPLDMFLEDCLDGTQVAASCAIDTLTSLLKALQAVNGTSWHDTFLGAWVAALRLVQRERDPIEGPVPRLDTRLCILLSITTLSIADIIDEEEVTIVDEIEHNTTSQWKEKQVPGKRRKDLVSSLQVLGDYEGLLAPPQSVISVANQAAAKAVMFISGLTVGSGYFECIGMTDVPMNCCKQYSSLFKCVESVDVSDFFVSFCDCIRPCMSSAQILNHRHLLAAGNLRHLIVEACIARNLLDTSAYFWPGYVNGRINQIPHNVSGQVLGWSTLMKGAQLIPSMINALATTPASRYADTQELRRLQSRQLCKLEEGKSDEFGNFWQSRQLEKIFEIAVNGSDDEKASAATILCGASLIRGWNIQYSEELTMVFSSFLIIPHCLQEHTVRYVVKLLSLPIPKDYSGSESHLISYAPMLNSVLTGISSVDSVQIFSLQGLVPELAGALMAICEAFGSSVPNISWTLPTGEKITVHAVFSNAFILLMRLWKFNHPPLEHHVLGNGAPVGSQLTPEYLLLLRNSLVASASNMPKERNNSRRLPKIAGSSSPHPIFVHSFPKMKVWYRQHQACIASPLSGLVQGTPVHQLVDGLLNMMFRKMNKGGSLTVTSGNSGSSLSSSSGPGSEDASIGLKLPAWEILEAVPFVVDAALTACSHGRLSPRDLATGLKDLADFLPASLATMVSYFSAEVTRGVWKPAFMNGTDWPSPAANFSTVEEHIKKILETTGVNVPSLVAGGSAPATLPLPLAAFVSLTITYKLDRVSERFLNLAGPALESLAAGCPWPSMPIVASLWAQKVKRWNDFLIFSASRTVFQQNRDAVVQLLKSCFTATLGLSPASICSNGGVGALLGHGFGSHFSGGFSPVAPGILYLRIYRSIRDIMFVTETILSLLVFSVKEVAANGLSRERIDKLKKTKYGARYGQVSLSAAMSKVKLAAELGASLLWLSGGSGLILTLVQETLPSWFLSMHGSEQEGGSGGMTAMLVGYTLAYFTVLCGAFAWSVESMPGAKRRARILGKHMEFLAGALDGKITLGCDWSTWRAYVTCFVGLMVRSAPIWVTEMEVDVLKRVSRGLRQWNEEDLALALLAGGGISAMGAAAELIISGGE
Length1388
PositionTail
OrganismCinnamomum micranthum f. kanehirae
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Magnoliidae> Laurales> Lauraceae> Cinnamomum.
Aromaticity0.08
Grand average of hydropathy0.163
Instability index42.47
Isoelectric point6.33
Molecular weight151028.66
Publications
PubMed=30626928

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23308
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.47|      12|     340|     885|     896|       1
---------------------------------------------------------------------------
  885-  896 (22.72/10.33)	GGSLTVTSGNSG
 1221- 1232 (23.75/11.13)	GASLLWLSGGSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.72|      38|      73|     737|     776|       3
---------------------------------------------------------------------------
  737-  776 (62.77/40.80)	AFGSSVP...NISWTLP..TGEKiTVHAVFSNAFIlLMRLWKFNH
  808-  850 (63.95/33.94)	ASASNMPkerNNSRRLPkiAGSS.SPHPIFVHSFP.KMKVWYRQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     633.29|     203|    1032|     102|     340|       4
---------------------------------------------------------------------------
  102-  340 (298.53/214.31)	HLSQvfGIQECEPGVLVVE.........FVFSIVWQLLEATLDDEGLLELTTER.....KSIWATRSQDMEIDYENSfderrtenydklqkaNTVMAIEL.............IvqflrqklvsrlLYLARQNMPShWggFmqrLRLLGTNSSAlRNSTISPEILLKSSSLYTP..KSFGLECKPSPHQDSRAVIASASLTSSAGDCFGPS...T.SALWIPLDMFLEDCL..DGTQVAAS......CAIDTLTSLLKA.LQAVNGTSWHDTFL.GAWVAAL
 1051- 1130 (47.76/10.98)	..................................................................................................................................................................................................LAGPALESLAAGCPWPSmpiV.ASLWAQKVKRWNDFLifSASRTVFQ......QNRDAVVQLLKScFTATLGLSPASICS.NGGVGAL
 1138- 1376 (286.99/148.87)	HFSG..GFSPVAPGILYLRiyrsirdimFVTETILSLLVFSVKEVAANGLSRERidklkKTKYGARYGQVSLSAAMS...............KVKLAAELgasllwlsggsglI............LTLVQETLPS.W..F...LSMHGSEQEG.GSGGMTAMLVGYTLAYFTVlcGAFAWSVESMPGAKRRARILGKHMEFLAGALDGKI...TlGCDWSTWRAYV.TCF..VGLMVRSApiwvteMEVDVLKRVSRG.LRQWNEEDLALALLaGGGISAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.68|      10|      19|     591|     600|       5
---------------------------------------------------------------------------
  591-  600 (19.19/13.61)	QSRQLCKLEE
  611-  620 (18.48/12.83)	QSRQLEKIFE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.18|      12|      19|     450|     461|       6
---------------------------------------------------------------------------
  450-  461 (23.96/19.98)	SGYFECIGMTDV
  470-  481 (21.22/16.65)	SSLFKCVESVDV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23308 with Med33 domain of Kingdom Viridiplantae
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