<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23295

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMATKRKEEEVALPAFRLLHTAAQTLTQRSSSILSKSGVSLLLLEILNYRLLPLYRYHGKSKALMYDVAKIISMIKGKRGEHRLFRLAENLCMNLILSLRDFFLVKKDLKGPTEFTETLNRITIMSLAITIKTRGIAEVDHMVFLTPLLEQIMSTSQHTWSDKTMRHFPPLIREILNGRLDKRGQAIQAWQQAETTVINQCTQLLSPSADPTYVMTYISHSFPQHRQYLCAGAWMLMNGHPESIISANLARVLKEFSPEEVTSNIYTMVDVLLHHIQIELQHGHLFQDLLLKACANLVFFIWTHELLPLDILLLALIDRDDDPHALHIAITLIEKQELQQRVKQFCLNRGPPDHWVHSGTFKRAELQKALGNHLSWRDRYPPFFDDIAARMLPVIPLIIYRLIENDGTDFAERVLALYAPLLAYHPLRFTFVRDILAYFYGNLPNKLILRILNVLDVSKIPFSESFPLHLRSSNPVICPPPDYFATLLLGLVNNCIPPLNSKSKSGSMGDTSGNSGRVTLNKTQSSSQFGATNTLEGQRAFYQNQDPGTYTQLVLETAVIEILSLPVTAPQIVSSLVQIVMHVQPTLIQSSNGLQGMTSAGQGSVLPASPSGGSTDSMNTTRSTPSTSGTCAANFVSKSGYSCQQLSCLMIQACGLLLSQLPPDFHLQLYVEAARIIKDCWWLTDGKRSPKELESAVGYSLLDPTWAAQDNTSTAIGNIVALLHSFFSSLPQEWLEGTHAVIKQLRPVTSVAMLRIAFRIVGPLLPRLAFARPLFMKVCLIYSINMVGFPLRI
Length792
PositionTail
OrganismCinnamomum micranthum f. kanehirae
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Magnoliidae> Laurales> Lauraceae> Cinnamomum.
Aromaticity0.08
Grand average of hydropathy0.058
Instability index45.50
Isoelectric point8.79
Molecular weight88730.19
Publications
PubMed=30626928

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23295
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     277.37|      88|     326|     337|     461|       1
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  346-  437 (151.91/150.41)	LNRGPPD................HWVHSGTFKRAELQKALGNHL...SWRDR.............YPPFFDDIAARMLPVIPLIIYRLIENDGTDFAERVLALYAPLLAyhplRFTFVRDI.....LAY
  657-  781 (125.46/64.14)	LSQLPPDfhlqlyveaariikdcWWLTDGKRSPKELESAVGYSLldpTWAAQdntstaignivalLHSFFSSLPQEWLEGTHAVIKQLRPVTSVAMLRIAFRIVGPLLP....RLAFARPLfmkvcLIY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     229.38|      76|     442|      41|     129|       2
---------------------------------------------------------------------------
   41-  129 (110.59/93.62)	LLLEILNYRLLPLyryHGKSKA.LMYDVakiiSMIKGK.....RGEHRLFRlaenlCMNLILSLRDFFLvKKDLKGPTEFTETLNRITIMSLAIT
  486-  567 (118.79/70.26)	LLLGLVNNCIPPL...NSKSKSgSMGDT....SGNSGRvtlnkTQSSSQFG.....ATNTLEGQRAFYQ.NQDPGTYTQLVLETAVIEILSLPVT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23295 with Med23 domain of Kingdom Viridiplantae
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