<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23292

Description Mediator of RNA polymerase II transcription subunit 15a isoform X1
SequenceMDSNNWRPPQGEPSMDGGDWRNQLMPESRQRIVNKIMETLKRHLPISGPEGLVELRKIAVRFEEKIYTAATSQSDYLRKISLKMLTMETKSQGNSGGNQNPSDPASQSLQQQVRNPGQPLPIPLGNQSQTRQQLLPQNLQNAIASAAAQSSPSLQSALSSVTGLTQTTMSNVVGQNSNLQTMPGISHSSVNNSVGQGVQSNMFSNSQRQMQGRQHPQQVLPQQHQQSQNPQQFYQQQMLKQKLQQGNMQTSLLQSHMQQQQSSLLQPNQMQPSQQSLMQMPSGLQSSQATLQQMQSSIMQSASQSGLQQNHLQQNQQSSVQQSGQSSLQQHPQSVLRQQQQTQPPSVHQQTSVLHQQQTQINQQPILLSQQQQQLMGQQPSGTNMQQNQLLAQQNSVPDVQQQQQQHQQQMLLGQQNNFPNMQQQQLLSQQNKNLHQSQQLGPQSNVSGIQQQQQLIGSQPGPGVSNLQQHQHSVNMLQQSKVAAQQQQQQQQQQQQQQQQQTQQTSTLLPSQGQQSQSQPPQQLLSQSQPAQLQQQPNTLQREMQQRIQSSGALLQPQRALPEASSTSMDSTAQTGHVGVVDWQEEVYQKIKYMKELYLPELNELYQKIAIKCQQHDALVLQPKQSDPIEKLRLFKGMLERMITFLQVPKSNISPTYKDKLAQYEKQIVSVLHSNRHKKPASQQPGQQHLQQSVGQSHSMTQQSQSQVSQLQQHESLVNSMQPMNMQGSVTSMQATAVTNSQHGSMPLPTHMGVQAAQQNMMNAMQTNSNLDSGPVHSMNSLPQGVVGSLPQNGVGPLQQNTINASQQTNMSALSQNNINQSQTNVSSLQATSNILQPQHLKQQQQEQLMQSQHLKQQYQQRHMIQQLFHQQQKQQQILQQQQQQQQQQQQQQQQPQLQQQFQHQQLHPQQKQQQPSQLQPQQMQQLHQMSEMNDLKVRPGAGVKPGLFTQTHLVGQRPTPYHQQLKTSAPFAISSPQLLQATSPQLSQHSSPQIDQQNLLSNLSKVGTPLQSANSPFTATPPTPAAPSVIPGDSEKQAPAISSVSNAGNIGHQQTAHGLTQAQSLAIATPGISASPLLAESSLDGNQGTAPTNISGKMSARERPLERLIKAVRSISPKAFSSSVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNFMSHDGSAATKKMRRHTSAMPLNAVSSVGSVNDSFKQLSSMETSELESTATSRIKRHRIETNHTLLEEVREINHRLIDTVVDISDEDIDSIAAAAEGEGTVVKCSFNAVALSPNLKSQYASPQMSPILPLRLLVPSNYPNCSPILLDKLPIEPSKESEDLSVKAKMTFNIYLRGLPQPISLGEMARTWDVCARKVISEYAQQSGGGSFSSRYGTWENCVSA
Length1389
PositionTail
OrganismCinnamomum micranthum f. kanehirae
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Magnoliidae> Laurales> Lauraceae> Cinnamomum.
Aromaticity0.03
Grand average of hydropathy-0.811
Instability index78.61
Isoelectric point9.46
Molecular weight153744.12
Publications
PubMed=30626928

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23292
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     820.14|      88|      88|     366|     453|       1
---------------------------------------------------------------------------
  110-  197 (69.68/ 9.54)	....QQQ...V.RNPGQPlpiPLGNQS.QtR....QQLLPQnlQNAI...ASA.AAQS....SPSL.....Q....SAL.........SSV.....TGLTQTTMsnVVGQNSNLQTMPGI...S..................H.S.SVN....NSV......G......QG
  201-  287 (100.39/18.06)	NMFSNSQ...R.QMQGRQ........H.P.Q.....QVLPQ..QHQ.....QS.QNPQ....QFYQ.....Q....QMLK...QklQQGNM.....QTSLLQSH..MQQQQSSLLQPNQM...Q..................PsQ.QSLmqmpSGL......Q......SS
  289-  363 (97.50/17.26)	ATLQQMQ...S.SIM.QS...ASQSGL.Q.Q....NHL..Q..QNQQ...SSV.QQSGqsslQQHP.....Q....SVLR...Q..QQQT..........QPPS..VHQQTSVLHQQQTQ...I..................N...........................Q
  366-  453 (162.62/35.32)	ILLSQQQ...Q.QLMGQQ...PSGTNM.Q.Q....NQLLAQ..QNSV...PDV.QQQQ....QQHQ.....Q....QMLL...G..QQNNF.....PNMQQQQL..LSQQNKNLHQSQQL...G..................P.Q.SNV....SGI......Q......QQ
  456-  548 (96.00/16.85)	LIGSQPGpgvS.NLQQHQ...HS.VNMlQ.Q....SKVAAQ..QQQQ...QQQ.QQQQ....QQQQ.....QtqqtSTLLpsqG..QQSQ.......SQPPQQL..LSQS.....QPAQL...Q..................Q.Q.PNT..lqREM......Q......QR
  554-  666 (63.37/ 7.79)	ALL.QPQ...R.AL..PE...ASSTSM.D.S....T...AQ..TGHV...GVV.DWQE....EVYQkikymK....ELYL...P..ELNELyqkiaIKCQQHDA..LVLQPK...QSDPI...EklrlfkgmlermitflqvP.K.SNI....SPTykdklaQ......YE
  780-  839 (59.54/ 6.73)	..............MNSL...PQGV.....V....GSL..P..QNGV...GPL.QQNT....INA..................S..QQTNM.....SA........LSQNNIN..QS...........................Q.TNV....SSL......QatsnilQP
  840-  916 (106.33/19.71)	QHLKQQQ...QeQLMQSQ...HLKQQY.Q.QrhmiQQLFHQ..QQKQ...QQIlQQQQ....QQQQ.....Q....QQ........QQQQQ.....PQLQQQ...........F.QHQQL...H..................P.Q.QK..............Q......QQ
  917-  995 (64.71/ 8.16)	......P...S.QLQPQQ........M.Q.Q....LHQMSE..MNDLkvrPGA.GVKP....GLFT.....Q....THLV...G..QR........PTPYHQQL..KTSAPFAISSPQLLqatS..................P.QlSQH....SSP......Q........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.21|      15|      15|    1290|    1304|       2
---------------------------------------------------------------------------
 1290- 1304 (29.25/16.75)	PQMSPILPLRLLV.PS
 1307- 1322 (25.96/14.01)	PNCSPILLDKLPIePS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      56.33|      19|      21|    1117|    1135|       4
---------------------------------------------------------------------------
 1125- 1147 (19.93/ 9.23)	SVSDIGS.VVSM.idrI..AGSApGNG
 1148- 1171 (18.25/ 7.82)	SRAAVGEdLVAMtkcrL..QARN.FMS
 1192- 1208 (18.15/ 7.74)	AVSSVGS.V........ndSFKQ.LSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.30|      25|      27|     724|     748|       5
---------------------------------------------------------------------------
  724-  748 (46.81/21.14)	P..MNMQGSVTSMQATAVTNSQHGSMP
  750-  776 (39.48/16.52)	PthMGVQAAQQNMMNAMQTNSNLDSGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     118.70|      34|      36|    1025|    1058|       6
---------------------------------------------------------------------------
 1004- 1047 (45.27/28.12)	NLSKVGTPlQSAnspftatppTPAAPSVI..PGD.SEKQAP......AISSVS
 1048- 1084 (44.83/27.76)	NAGNIGHQ.QTA......hglTQAQSLAIatPGI.S..ASP......LLAESS
 1085- 1118 (28.60/14.13)	LDGN...Q.GTA........pTN.....I..SGKmSARERPlerlikAVRSIS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23292 with Med15 domain of Kingdom Viridiplantae
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