<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23291

Description Mediator of RNA polymerase II transcription subunit 15a isoform X1
SequenceMCVKSYGAPDSVLSLILTNHRQFHLMTSLDSTAQAGHPGATDLKGEIYQKIKSMKELYLPELTELHRKITMRCQQFPKSSILPTYKEKLPQLEKQIINYLAKNGCTKPAASQQSGHQQLQESVGQPHLLMQQPESQIHQLQQQENQGQQSSDVEGLDVSDKDEYDTEDSFINDTELVATAHTTDRCCSCSSDSYNSTLSSNSYKLQKQLSQLHQETDLNDLKVRPGAGVKPGMFPQRHLTGQQETISTAKDNSSSPSFFSSVPSCCITSTSSAFIPIDQPREFSFDSPNSGNIFAICSLSLLWNPPSHLCRAFHWDTWDPGLPFANCSVDGNQGNAPQNIFGELSAPERPSERLTRAVRLAAVRRVGVGGVGPISALRTGFDAEGPAGAGGVGFTSVVGPAVGGGRGLAVVEIVTVGPAGAGGTGLVSLDEAFGAAGGNGGGGGPGLAGDGPDLVVVGTAGAGGGSFDMMGTVTSARLGGEDPTGLVLVGSAEVGGAGLPVVGPAGAIFVGGGGGGGGNGDGTRAIVTGTIVPPEAGGGNDATGLVVVGPSLATSPLKGSGDCGPPVAGSGPEVILRSGLNVGLILRALNTFSQMPTGLG
Length600
PositionTail
OrganismCinnamomum micranthum f. kanehirae
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Magnoliidae> Laurales> Lauraceae> Cinnamomum.
Aromaticity0.05
Grand average of hydropathy-0.178
Instability index42.74
Isoelectric point5.21
Molecular weight61587.20
Publications
PubMed=30626928

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23291
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     181.93|      28|      38|     403|     430|       1
---------------------------------------------------------------------------
  384-  398 (27.96/ 7.43)	EG...............PAGAGG....VGFTSVV
  403-  430 (53.07/20.17)	GGGRGLA..VVEIVTVGPAGAGG....TGLVSLD
  442-  468 (44.06/15.60)	GGGPGLAgdGPDLVVVGTAGAGG.....G..SFD
  478-  499 (29.75/ 8.34)	LGGED....PTGLVLVGSAEVGG....AGL....
  522-  549 (27.09/ 6.98)	.GTR..A..IVT.GTIVPPEAGGgndaTGLVVVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.51|      34|     110|      63|      96|       2
---------------------------------------------------------------------------
   63-   96 (60.04/42.87)	TEL..HRKITMRCQQFPKSSILPTYKEKLPQLEKQI
  174-  209 (54.48/38.23)	TELvaTAHTTDRCCSCSSDSYNSTLSSNSYKLQKQL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     112.04|      29|      29|     269|     297|       8
---------------------------------------------------------------------------
  251-  279 (25.47/11.50)	......DNSSSPSFFSsvpsccITSTSSAFIPIDQ
  280-  308 (55.89/33.44)	PREFSFDSPNSGNIFA......ICSLSLLWNPPSH
  310-  327 (30.67/15.25)	CRAFHWDTWDPGLPFA......NC...........
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23291 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KPAASQQSGHQQLQESVGQPHLLMQQPESQIHQLQQQENQGQQSSDVEGLDVSDKDEYDTEDSFINDTE
107
175










Molecular Recognition Features






MoRF SequenceStartStop




NANANA