<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23290

Description Mediator of RNA polymerase II transcription subunit 19a isoform X1
SequenceMTENKRPLNVDGAARSKLSPVDIGGVLRMKGRKSWSCSLSSLELKMNEAEVMAILETLQIFSSAHNDRVEDLFDGGFTIVGLCGFGDIMDQDSRKFGRGPRELTGAVDLIHHYKLLAHHDFFCKRSLPLAISETHYLHNVVGDTEIRKGEGMELDQLFHDTFIKETSAHIEPFDLDTLRQAFQLRETAPIDLPSAEKGIPTTGGKSKNESKDKERKHKKHRDRDKEKDKEHKKRKHRHKDRSKDKDKEKKKDKGGHHDSGADHSKKHHDKKRKHDGSEDLGDIHKHKKNKHKSSKVDDMGAIKELSCSDSKVLKACVSRMAATIGHRKESP
Length331
PositionHead
OrganismCinnamomum micranthum f. kanehirae
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Magnoliidae> Laurales> Lauraceae> Cinnamomum.
Aromaticity0.04
Grand average of hydropathy-1.044
Instability index46.85
Isoelectric point9.27
Molecular weight37520.09
Publications
PubMed=30626928

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23290
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.78|      15|      15|     219|     233|       1
---------------------------------------------------------------------------
  219-  233 (27.99/10.68)	KHR..DRDKEKDKEHKK
  235-  251 (21.79/ 6.77)	KHRhkDRSKDKDKEKKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.10|      15|      16|     267|     281|       2
---------------------------------------------------------------------------
  267-  281 (29.15/12.20)	HHDKKRKHDGS..EDLG
  284-  300 (23.95/ 8.82)	HKHKKNKHKSSkvDDMG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.48|      15|      15|     133|     147|       4
---------------------------------------------------------------------------
  133-  147 (26.62/21.43)	ETHYLHNVVGDTEIR
  150-  164 (26.86/21.69)	EGMELDQLFHDTFIK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23290 with Med19 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LRETAPIDLPSAEKGIPTTGGKSKNESKDKERKHKKHRDRDKEKDKEHKKRKHRHKDRSKDKDKEKKKDKGGHHDSGADHSKKHHDKKRKHDGSEDLGDIHKHKKNKHKSSKVDDMGAIKELSCSDSKVLKACVSRMAATIGHRKESP
184
331










Molecular Recognition Features






MoRF SequenceStartStop




1) KDKERKHKKHRDRDKEKDKEHKKRKHRHKDRSKDKDKEKKKDKGGHHDSGADHSKKHHDKKRKHDGSEDLGDIHKHKKNKHKS
2) KVDDM
211
295
293
299