<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23281

Description Mediator of RNA polymerase II transcription subunit 8
SequenceMAMAMAGGGASTGTEGGVGVGGGDEAAANQTKVERLNQAVQQQLNLESVKTRAVGLSKAISRILEDFDAIARSNSVPKWQDVLGQFSMVNLELFNIVEDIKKVSKAFVVNPKNVNQETATILPVMLSSKLLPEMEAEDNSKREQLLHGLQNFPISAQIEKLKMRIDMIGAACESAEKVIADARKAFGLGTRQGPTILPTLDKVQAAKIQEQETLLRAAVNFGEGLRIPGDQRHLPHVLPMHLVDVLNFGDGAQNLVDTSGGYPKNAPPSMPSGNTTTQGSVLQGPGPQLIGRSVPSPSGVTGASSFDNTSASPLPYANSPRSGTGMMNTPSPQQQTQQQQQQQQQRKMMQLPQHQQQFLAQQQMRQTSTPGGLGQNSVQQLQDIQGQAQQKFQPVHGQHQMQYSQPLGHQQFQSRQMQPGHVQHSIGQNQISQGNQLRGHLGQFTGSANNALFNAAQSSPNSQMISNMSAGIPSQSLLPRVQFGLSGGHPQRSHASQILGDQMFNMGAANSSNMVPMQQQQHSTQGGYGNIPTNTQNLQPGMVNLQNTSQNPNYPQQRQQNPQ
Length563
PositionHead
OrganismCinnamomum micranthum f. kanehirae
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Magnoliidae> Laurales> Lauraceae> Cinnamomum.
Aromaticity0.04
Grand average of hydropathy-0.614
Instability index53.18
Isoelectric point9.21
Molecular weight60718.38
Publications
PubMed=30626928

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23281
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     223.91|      51|      51|     337|     387|       1
---------------------------------------------------------------------------
  333-  354 (33.99/ 6.55)	QQQ.................................tQQQQQQ.....QQQRKMMQLPQH
  355-  406 (88.01/27.15)	QQQFLAQQQMRQTSTPGGLG...QNSVQQLQDIQGQaQQKFQP.....VHGQHQMQYSQP
  409-  440 (45.88/11.08)	HQQF.QSRQMQPGHVQHSIG...QNQISQGNQLRGH........................
  512-  557 (56.03/14.95)	SNMVPMQQQ..QHSTQGGYGnipTNT.QNLQP...........gmvnlQNTSQNPNYPQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     135.48|      31|      33|     232|     263|       2
---------------------------------------------------------------------------
  186-  204 (21.97/ 6.67)	...FGLG...........TRQGPTILPtLDKV....Q
  218-  244 (46.98/22.05)	AVNFGEGLR.....IPGDQRHLPHVLP.MHLV....D
  245-  280 (44.88/24.66)	VLNFGDGAQnLVDTSGGYPKNAPPSMP.SGNTttqgS
  281-  297 (21.66/ 6.48)	VLQ.GPGPQ.LIGRSVPSP..................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     191.77|      65|     356|      83|     156|       3
---------------------------------------------------------------------------
   83-  156 (89.26/71.86)	LGQFS.MVNLELFNIVEDiKKVSKafVVNPKNVNQETATILP.VMLS.SKLLPEmeaedNSKREQLLhGLQNFPISA
  441-  508 (102.51/57.23)	LGQFTgSANNALFNAAQS.SPNSQ..MISNMSAGIPSQSLLPrVQFGlSGGHPQ.....RSHASQIL.GDQMFNMGA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23281 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QNLVDTSGGYPKNAPPSMPSGNTTTQGSVLQGPGPQLIGRSVPSPSGVTGASSFDNTSASPLPYANSPRSGTGMMNTPSPQQQTQQQQQQQQQRKMMQLPQHQQQFLAQQQMRQTSTPGGLGQNSVQQLQDIQGQAQQKFQPVHGQHQMQYSQPLGHQQFQSRQMQPGHVQHSIGQNQISQGNQLRGHLGQFTGSANNALFNAAQSSPNSQMISNMSAGIP
2) QSLLPRVQFGLSGGHPQRSHASQILGDQMFNMGAANSSNMVPMQQQQHSTQGGYGNIPTNTQNLQPGMVNLQNTSQNPNYPQQRQQNPQ
253
475
473
563










Molecular Recognition Features






MoRF SequenceStartStop




NANANA