<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23269

Description mediator of RNA polymerase II transcription subunit 15a-like isoform X1
SequenceMDKNKMILGTQGTNIATDRWKTAEFRHKIVRKVMDELIENGMPYQKFSLSELANSVERFEMKVYNSAKTEEEYLALVKSKVKSIRALSRKYESKQLHTNASGSAGKDANIDWQELTYEKFQKLKDKYYRQLAPLYQKITIKLQEFESSTQYISSKELAKFKNNKTAMEYLFSLFDMNKSQITTEIKDRAGEAEHYIEMLLKTVSPNNQGNQTSDLQFKQPLGPSNSKNSQTNNMHLQEPRVAVQIGNSQPHSNQPSFAKEPGNAVQEQTKLAQQETGAFNVSINPSRISSSPMSKDNNNQFSQKSSVVSEEEPSPEMQRLIKALTNISPEALRASVSDIEEVVRLSDALPAAAFIGALPDMVDELGLPILHIPEGWKMPRSFVATAFDSTFLNVTNFGNQSTNTEESDFNSFTFQAKRPRNAENKHLLAEIKEINNRFIDCEVIIDEKDNIEQPFGIATEQTEGLVIKIIFNAVSISQNLVYEFTTDKKSLITPLRLLVPPSYPSSSLVILDELPFEISDDLRALTERTKAKLRFNLQSMNQPWVLKDITRLWERCAREAINEYALTIGGGTFTSVHGGWEVCRF
Length585
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.08
Grand average of hydropathy-0.542
Instability index53.00
Isoelectric point6.06
Molecular weight66333.26
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23269
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.49|      16|      17|     205|     220|       1
---------------------------------------------------------------------------
  205-  220 (30.43/19.73)	PNNQGN.QTSDLQFKQP
  223-  239 (26.06/15.84)	PSNSKNsQTNNMHLQEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.52|      20|     155|     253|     273|       3
---------------------------------------------------------------------------
  253-  273 (31.96/28.24)	NQPSF.AKEPGNAvQEQTKLAQ
  410-  430 (31.56/22.20)	NSFTFqAKRPRNA.ENKHLLAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.66|      21|      31|     320|     341|       4
---------------------------------------------------------------------------
  320-  341 (28.85/24.49)	LIKALTNISPEaLRASVSDIEE
  354-  374 (35.82/25.47)	FIGALPDMVDE.LGLPILHIPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.87|      44|      90|       9|      55|       5
---------------------------------------------------------------------------
    9-   55 (68.52/61.50)	GTQGTNIATDrWKtaEFRHKIVRKVMDELIENGMP.YQKFS..LSELANS
  102-  148 (68.35/49.46)	GSAGKDANID.WQ..ELTYEKFQKLKDKYYRQLAPlYQKITikLQEFESS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.37|      34|      63|     443|     481|       6
---------------------------------------------------------------------------
  443-  481 (52.01/44.83)	VIIDekdniEQPFGIATE...QTEGLVIKIIFNAVSISQNLV
  509-  545 (56.36/36.73)	VILD.....ELPFEISDDlraLTERTKAKLRFNLQSMNQPWV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23269 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IEMLLKTVSPNNQGNQTSDLQFKQPLGPSNSKNSQTNNMHLQEPRVAVQIGNSQPHSNQPSFAKEPGNAVQEQTKLAQQETGAFNVSINPSRISSSPMSKDNNNQFSQKSSVVSEEEPSPEMQRLIKAL
196
324










Molecular Recognition Features






MoRF SequenceStartStop




NANANA