<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23263

Description mediator of RNA polymerase II transcription subunit 16-like isoform X2
SequenceMNQIKEDFDGEELSFSNSNSKNEATVTVSVPKEEDEAEEEEEEEEDPMEYPMEVDEQDSVSLSPATVFRIRLRQPTSNLLHKMPLPEICRNFSAVSWCGKLNAIACASETCARIPRSTVNPPFWIPIHIVIPERPTESAVFNVIAARWPNFLCVCSVFSSGSVQLHWSQWPPSQNATPPKWFYTSKGLLGCGPSGIMAGDAIITESGAMHVAGVPIVNPSTIVVWEVMPGPGNGFQLTPKISINNGVPPLSPPNWSGFAPLAAYLFSWQDYLLSAEKQGRNQTDQNLGESIPLHCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTCGGSVIAVVIVEGQYMSPSDPDEGPSITGWRVQRWESSFQHVVLHPIFGNPTSSMGGKPPMQTIWQSKVDMSIPPTNDFKSRQTPPIGMSANVQKASESGADKSKGVNFDPFDLPSDIRTLARVVYSAHGGEIAIAFLRGGVHIFSGLNFAPVANYQINVGSAIAAPAFSSTSCCSASVWHDASKDHTILKIIRVLPPAIPIGQVKANSSIWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAILDADFHSLPTAQHRQQYCPSLDRIKCRLLEGSNAQEVRAMVLDMQARLLLDMLGKGIESALINPSALVPDPWQVSGETLSNIDPEAVSVEPALIPCIQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGTGSNRSMVASPSQNSTTPATSQGGENGTTSSSGNTQMKAWVQGAIAKISSTSDGVSNLTPNPPISGPSSLMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRSQLPRYMSSAQRTADTNSQKPHPNASVPCKMEEVAKPVSSGVRSDDSQTGRVGQPVNGSKGGEEPSPGRSRLGTGNAGQGYTFEEVKVLFLVLMDLCRRTSGLQHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNTFGGPWTDPNDEDCANDSPKLVSLNPLDSSSLENSDVYYAANGLWPRKRRLSERDAAFGLNTSVGLGAYLGIMGSRRDVVTTLWKTGLEGVWYKCIRCLRQTCAFASPGSTNLPNQNDREIWWVSRWAYGCPMCGGRWARVV
Length1145
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.08
Grand average of hydropathy-0.203
Instability index47.99
Isoelectric point5.71
Molecular weight124103.82
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23263
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     525.19|     113|     137|     155|     290|       1
---------------------------------------------------------------------------
  135-  251 (196.96/120.07)	PTESAVFNVIAA...RWPNFL....................cvCSVFSSGSVQLhwSQWPPSQNAT.PPKWFYTSKGLLG......CGPSG.........IMAGDAIITESGAMHVAGV.......PIVNPSTIVVWEVMPGPGNGFQ...LTP....KISINNGVPPLS
  252-  393 (150.00/115.80)	PPNWSGFAPLAAylfSWQDYLlsaekqgrnqtdqnlgesiplhCSPVSNFSAYV..SPEAAAQSAA.TTTW...GSGVTAvafdptCGGSV.........IAV...VIVE.GQYMSPSD.......PDEGPS.ITGWRVQRWE.SSFQhvvLHPifgnPTSSMGGKPPMQ
  394-  477 (110.56/59.81)	.TIWQSKVDMS.......................................................iPPTNDFKSR...Q......TPPIG.........MSANVQKASESGADKSKGV....nfdPFDLPSDIRTLARVVYSAHGGE...IAI....AF.LRGGVHIFS
  729-  801 (67.68/27.61)	............................................................PSQNST.TPA...TSQG..........GENGttsssgntqMKAWVQGAIAKISSTSDGVsnltpnpPISGPS..............S....LMP.....ISINTGTFPGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.43|      23|     532|     545|     572|       2
---------------------------------------------------------------------------
  545-  567 (46.57/19.92)	RAIAER....FWWSLLVGVDWWDAVGC
 1080- 1101 (40.82/16.14)	RDVVTT....LWKTGLEGV.WYKCIRC
 1114- 1134 (30.03/15.21)	TNLPNQndreIWW.....VSRW.AYGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.90|      13|     113|     695|     707|       3
---------------------------------------------------------------------------
  695-  707 (26.05/15.64)	HFITRLRRYASFC
  811-  823 (26.85/16.31)	HFLHRLCQLLLFC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     137.54|      47|     286|     604|     659|       6
---------------------------------------------------------------------------
  604-  659 (68.14/55.82)	PSLDRikCRLLEGSNAQ.....EVRAMVLdmqarLLLDMLGK..GIESALinPSALV.PDPWQV
  893-  947 (69.40/36.71)	PSPGR..SRLGTGNAGQgytfeEVKVLFL.....VLMDLCRRtsGLQHPL..PVSQVgSSNIQV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23263 with Med16 domain of Kingdom Viridiplantae
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