<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23261

Description mediator of RNA polymerase II transcription subunit 16-like isoform X2
SequenceMLAVGSTSMSGVRILQLQQSGYQECLRWLSSKSSAPTNPKVTFEEKFLSQQSQTSARWPNFLCVCSVFSSGSVQLHWSQWPPSQNGSTPSWFHTSKGLLGCGPSGIMAGDAIITDSGAMHVAGVPIVNPSTIVVWEVTPGPGNSFQATPKTSTASGVPPLISPNWAGFAPLAGYLFCWQDYLLSQAKQGKKLTDKNLGDAVPLYCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRAGSVIAVVIVEGQYMSPSDPDEGPSITGWRVQRWESSLQQVVLHPIFGNPTSSMGGQPPMQTVWQSKVDLSIPPTNDFKCHQSPAIGMSTDVQKLSEPVPDKSKRVNFDPFDLPSDIRTLARIVYSAHGGEIAIAFLRGGVHIFSGPNFAPVDNYQVTVGSSIAAPAFSSTSCCSASVWHDTGKNCTILKIIRVLPPPTPISQVKANSSTWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSVQHRQQYGPSLDRIKCRLLEGSNAQEVRAMVLDMQARLLLDMLGRGIESAFINSSALVPELWQASGETLSSIDPETMAVEPALIPCVQAYVDAILDLASHFITRLRRYASFCRTLASHAVTAGTGSNRNLVASPTQSSATPATSQGGQNGSASSMGSTQLQTWVQGAIAKISNTTDGGSNPTPNPISGPSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLPRYMGAANRTTDTNIQKSNAPASGKVEEISKPVSAVAKSEDGLTGRAGQLMSGSKGSEEAPSGRSRLGSGNAGQGYTFEEVKVLFMMLMELCRRTAGLQHPLPVSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDPEDVDFANDQSKVVFSDPRDLSSVEHCDAYYGTHRLWPRKRRMSERDAAFGLNTSVGLGAYLGIMGSRRDVVTATWKTGLEGVWYKCIRCQRQTSAFASSGSTASPSQNEREMWWISRWAYGCPMCGGTWVRVV
Length1052
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.08
Grand average of hydropathy-0.165
Instability index45.90
Isoelectric point7.26
Molecular weight113516.18
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23261
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     494.93|     131|     137|     132|     268|       1
---------------------------------------------------------------------------
   65-  149 (87.45/38.60)	........................................................CSVFSSGSVQLhwSQWPPSQNGSTPSWfhtSK..GLLGCGPSGIMAGD..AIITDSGAMHVAGVPIV...NPS.tivvWEVTPGPGNSFQAT..P
  150-  287 (209.64/104.51)	KTSTASGVPPLiSPNWAGFAPLAgyLFCWQDYLLSQAKQGKKLTD.KNLGDAVPLYCSPVSNFSAYV..SPEAAAQSAATTTW...GS..GVTAVAFDPTRAGSVIAVVIVEGQYMSPSDPDE...GPSI..tgWRVQRWESSLQQVVlhP
  292-  405 (158.08/70.65)	PTSSMGGQPPM.QTVWQSKVDLS..IPPTNDFKCHQSPAIGMSTDvQKLSEPVPDKSKRV.NFDPFD..LP.SDIRTLARIVY...SAhgGEIAIAF..LRGG....VHIFSGPNFAPVDNYQvtvGSSI.....................
  991- 1037 (39.76/12.10)	...............................................................................TATW...KT..GLEGVWYKCIRCQRQTSAFASSGSTASPSQNER...EM......WWISRW...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.37|      35|      72|     663|     701|       2
---------------------------------------------------------------------------
  663-  701 (56.25/46.93)	TQLQTWVqGAIAKisnTTDGGSNPTPNPISGPSTFM..PIS
  738-  774 (57.12/34.98)	TQLPRYM.GAANR...TTDTNIQKSNAPASGKVEEIskPVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     234.08|      70|      74|     818|     890|       3
---------------------------------------------------------------------------
  818-  890 (111.84/78.38)	FEEVKvLFMMLMELCRRTA.GLQHPLPvSQVGSSNIQVRLHYIDGNYTVLPEVVEASLGPHmQNMPRPRGA...DAA
  894-  967 (122.24/73.06)	LRELE.LHPPAEEWHRRNMfGGPWSDP.EDVDFANDQSKVVFSDPRDLSSVEHCDAYYGTH.RLWPRKRRMserDAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.82|      25|     114|     590|     617|       4
---------------------------------------------------------------------------
  590-  617 (38.55/39.37)	PCVQAyVDAILDlaSHFITRLRRYASFC
  708-  732 (50.27/36.64)	PGTPA.VRLIGD..CHFLHRLCQLLLFC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23261 with Med16 domain of Kingdom Viridiplantae
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