<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23255

Description mediator of RNA polymerase II transcription subunit 15a-like isoform X2
SequenceMDKNKMILGTQGTNIATDRWKTAEFRHKIVRKVMDELIENGMPYQKFSLSELANSVERFEMKVYNSAKTEEEYLALVKSKVKSIRALSRKYESKQLHTNASGSGKDANIDWQELTYEKFQKLKDKYYRQLAPLYQKITIKLQEFESSTQYISSKELAKFKNNKTAMEYLFSLFDMNKSQITTEIKDRAGEAEHYIEMLLKTVSPNNQGNQTSDLQFKQPLGPSNSKNSQTNNMHLQEPRVAVQIGNSQPHSNQPSFAKEPGNAVQEQTKLAQQETGAFNVSINPSRISSSPMSKDNNNQFSQKSSVVSEEEPSPEMQRLIKALTNISPEALRASVSDIEEVVRLSDALPAAAFIGALPDMVDELGLPILHIPEGWKMPRSFVATAFDSTFLNVTNFGNQSTNTEESDFNSFTFQAKRPRNAENKHLLAEIKEINNRFIDCEVIIDEKDNIEQPFGIATEQTEGLVIKIIFNAVSISQNLVYEFTTDKKSLITPLRLLVPPSYPSSSLVILDELPFEISDDLRALTERTKAKLRFNLQSMNQPWVLKDITRLWERCAREAINEYALTIGGGTFTSVHGGWEVCRF
Length584
PositionTail
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.08
Grand average of hydropathy-0.546
Instability index53.07
Isoelectric point6.06
Molecular weight66262.18
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23255
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.58|      15|     155|     252|     272|       2
---------------------------------------------------------------------------
  236-  250 (26.99/10.21)	QEPRVAVQIGNSQPH
  258-  272 (25.59/24.38)	KEPGNAVQEQTKLAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.66|      21|      31|     319|     340|       3
---------------------------------------------------------------------------
  319-  340 (28.85/22.91)	LIKALTNISPEaLRASVSDIEE
  353-  373 (35.82/23.83)	FIGALPDMVDE.LGLPILHIPE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.37|      34|      63|     442|     480|       4
---------------------------------------------------------------------------
  442-  480 (52.01/41.27)	VIIDekdniEQPFGIATE...QTEGLVIKIIFNAVSISQNLV
  508-  544 (56.36/33.79)	VILD.....ELPFEISDDlraLTERTKAKLRFNLQSMNQPWV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.27|      41|      89|      12|      55|       5
---------------------------------------------------------------------------
   12-   55 (62.93/51.77)	GTNIATDrWKtaEFRHKIVRKVMDELIENGMP.YQKFS..LSELANS
  104-  147 (63.35/41.26)	GKDANID.WQ..ELTYEKFQKLKDKYYRQLAPlYQKITikLQEFESS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23255 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IEMLLKTVSPNNQGNQTSDLQFKQPLGPSNSKNSQTNNMHLQEPRVAVQIGNSQPHSNQPSFAKEPGNAVQEQTKLAQQETGAFNVSINPSRISSSPMSKDNNNQFSQKSSVVSEEEPSPEMQRLIKAL
195
323










Molecular Recognition Features






MoRF SequenceStartStop




NANANA