<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23247

Description mediator of RNA polymerase II transcription subunit 12-like isoform X2
SequenceMQTLLDDFFSKNTSQSTPHNRDQSPQMSYATSLKHRSSQLLPVSDGEEPSLHFRWWYVVRLLQWHHTEGLLLPSLVIDWIFHQLQEKQLLEIWQLFLPIVYGFLEIVVLSQTYVRTLAGVALSIIRDPAPGGSDLVDNSRRAYTAAALIEMLQYLIFAVPETFVTLDCFPLPFSVVSHTINDGNFVPKAIEAAEKIKNSSEDVVCTFRSKGLDAKYESLAFGRVISCIQKHAENLTKAVSPGYPGHCLAKAAQALDKSLVLGDIRGAYTFLFEDLYDGRSSEGWVAKISPCLRLSLKWFVNVNSSLVYSVFFLCEWATSDFRDFRTAPPCDIKFTGKKDLSQVHIAVRLLKMKLRNMHISSRQRNENTHHGVDYSAKCSSQHINWNNASKIKSSSKSMNQSICSSVIFESPGPLHDIIVCWIDQHVVHKGVGFKCLHLFIVELILAGIFYPLAYVRQLIVSGIMDTSVNMVELERQKRHCQILKQLSGNFVRHALEESEIIEGPLLIEALHVYLNERRLILRGSFSENHINGSSRANNSTVNKKHCTSSAKDGFSTVSIDQQKTVPSNKISDKVEKDNTCVENLKTAISVLLQLPKSLPNPNTTELGESQGSVKRLVRCYSKIDLMEATPGCEECRRAKKQKLSEERSSLDVEDTWWVKKGLKSLEPLKVDQPLKTTKQVTKSRHKTVRKTQSLAQLAASRIEGSQGASTSHVCDIKVSCPHHRTAMDGDTAKSVDGIRTSQYQDIVSLGRALKRLRFVEKKEITVWLMTVIRQFIGDSEKSIGKVGQFGRPVTTMDDRSSIRWKLEEDELSAILYLMDVSDDLVPAIKFLLWLLPKVCSSSNSTIHSGRNVLMLARNVDNQVCNVGEAFLLSSLRRYENILASADLIPEALSSVMDRAAAIIASNGRVSGSGALAFARYLLKKYSNVVSVIEWEKNFKTTCDKRLASEFESGGRLVDGEFGLPLGVPAGIEDPDDYFRQKISGGRLPSRVASGMRDVVQRNVEDAFHYLFGKDRKLFAAGSPKGFSLEKWDNGYQIAQHIVIGLIDCIRQTGGAAQEGDPSLVTSAVSAIVGSVGPSLAKLPDFSAGNNHPNISLATSSLNYAKCILRMHITCLCLLKEALGERQSCVFDIALAIEASNALAGVFAPSKASRSQFQMSPETDDTSATMSNDVVNSSSKIVLARTTKIASSVSALIVGAIIYGVTSLERMVTILRLKEGLDVVQFVRNSRSNSNGNARSTGAIKVDSSVEVHLHWFRLLVGNCRTICEGLVVDLLSEPSIVAFSRMQRTLPQRLVFPPAYSIFSFVIWRPFITSANVANREDTNQLYQTLTMAINDAMKHLPFRDVCLRDSQGLYDLIAADTSDLEFANLLELNGSDMRLNSTAFVPLCARLFLNAMVDCKMPQSIYTKDGGSCISGHGESKIHFTDSESKLQDQLVDVLEALQPAKFHWQWVELRLLLNELALIEKLQTHNVSLADAIQLSLPSSEKAAASENENNFIQILFTRLLVRPDAAPLFSELVHLFGKSLEDSMLLQAKWFLGGEDVLFGRKTIRQRLINIAETKGFSVKPHSLEPWGWCSPSTDPLTIKGGKRKVDSLSLEEGEVVEEGVNVKRSIKGFSQVFDSEGSTIKQQHGTERAFLELILPCIDQSSNESRYSFASGLIKQLSYIEQQIAVVTCGPGNPAASMPVTEGQTNKGNSRKTIKGGSLGLARRPTSSTDSSPPSPAALRASMSLRIQLLMRFLPILCTDGEPSVRNMRRTLASVTLRLLGSRIVLEDANILILLLRDFLNDCC
Length1792
PositionKinase
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.07
Grand average of hydropathy-0.111
Instability index48.29
Isoelectric point8.49
Molecular weight198674.73
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23247
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     321.22|     107|     599|     939|    1105|       1
---------------------------------------------------------------------------
  169-  283 (164.50/85.43)	FPLPFSVVSHTINDGNFVPKAIEAAE...KIKNSSEDVVctfrSKGLDAKYESLaFG...RVISCIQKHAENLTKaVSPGY..PGH.......CLAK...AAQALDKSLV...LGDIRGAYTFLFEDLYDgrSSEG
  961- 1088 (156.72/150.13)	FGLPLGVPAGIEDPDDYFRQKISGGRlpsRVASGMRDVV....QRNVEDAFHYL.FGkdrKLFAAGSPKGFSLEK.WDNGYqiAQHiviglidCIRQtggAAQEGDPSLVtsaVSAIVGSVGPSLAKLPD..FSAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     166.49|      47|     599|     648|     694|       3
---------------------------------------------------------------------------
  648-  694 (78.23/54.70)	SSLDVEDTWW..VKKGLKSL.E....PLKVDQPLKTTKQVTKSR.HKTVRKTQSL
 1203- 1239 (29.58/15.41)	...............GVTSL.ErmvtILRLKEGLDVVQFVRNSR.SNSNGNARS.
 1247- 1294 (58.68/38.91)	SSVEVHLHWFrlLVGNCRTIcE....GLVVDL.LSEPSIVAFSRmQRTL..PQRL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23247 with Med12 domain of Kingdom Viridiplantae
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