<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23240

Description mediator of RNA polymerase II transcription subunit 8-like isoform X2
SequenceMLSTKLLPEMETEDTSKRDQLLQGMQNLPIATQIDKLKARLDMIAGACEGAEKVLADTRKAYCFGTRQGPAIAPTLDKGQAAKIQEQENLLRAAVNVGEGLRLPGDQRHITASLPMHLADVFTVNEGPQSFPEGSSNNVYIKNTPLSSNSMGGQNSLLQNSGSQLLGRSAASPNVATNATFDNTAASPIPYANSPRSSTNMMNTPSPQQQTPQQQQQQPTVQQQQQQQRQKMMQLPQQQQQLLAQQQQFRQSAMQGLGQLHGQHQMQFSQQIGHQQFQGRQLTSGHVQHGIGQSQLNQGNQMARISQFSGAANNALFNAAQTTPNTQMIPNISAGISSQPLLPRMQFGLSGNNPQRNHASQMLSDQMFNMGGGNPGGMMSIQQQQQQQQSSQGAFGGLASNAQNLPSGMMTLQNTQQNHPNFSQQRQQNQQ
Length431
PositionHead
OrganismCicer arietinum (Chickpea) (Garbanzo)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> Hologalegina> IRL clade> Cicereae> Cicer.
Aromaticity0.04
Grand average of hydropathy-0.790
Instability index56.26
Isoelectric point9.55
Molecular weight46946.78
Publications
PubMed=26259924

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23240
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     286.81|      58|      58|     245|     302|       2
---------------------------------------------------------------------------
   67-  134 (41.09/ 7.80)	RQ...G...PAI.A.PT.L..DKG.QA................akiqEQENLLRAAVNvGE...GlRLP....GdqRHitaslP........M..HladvF...TVNEGPQSFpEG
  144-  218 (59.06/14.25)	TPLSSNSM..G..G.QNSLlqNSGSQL.........lgrsaaspnvaTNATFDNTAAS.PI...P.YANsprsS..TN.....M........M..N....TpspQQQTPQQQQ.QQ
  240-  279 (65.91/16.71)	QQL..........................................laQQQQFRQSAMQ.GL...G.QLH....G..QH.....Q........M..Q....F...SQQIGHQQF.QG
  280-  341 (69.86/18.12)	RQLTSGHVQHGI.G.QSQL..NQGNQM...................aRISQFSGAANN.ALfnaA.QTT....P..NT.....Q........MipN....I...SAGISSQPL...
  342-  425 (50.89/11.32)	..L..PRMQFGLsGnNPQR..NHASQMlsdqmfnmgggnpggmmsiqQQQQQQQSSQG.AF...G.GLA....S..NA.....QnlpsgmmtL..Q....N...TQQ.NHPNFsQQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23240 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QPLLPRMQFGLSGNNPQRNHASQMLSDQMFNMGGGNPGGMMSIQQQQQQQQSSQGAFGGLASNAQNLPSGMMTLQNTQQNHPNFSQQRQQNQQ
2) VFTVNEGPQSFPEGSSNNVYIKNTPLSSNSMGGQNSLLQNSGSQLLGRSAASPNVATNATFDNTAASPIPYANSPRSSTNMMNTPSPQQQTPQQQQQQPTVQQQQQQQRQKMMQLPQQQQQLLAQQQQFRQSAMQGLGQLHGQHQMQFSQQIGHQQFQGRQLTSGHVQHGIGQSQLNQGNQMARISQFSGAANNALFNAAQTTPNTQMIPNISAGIS
339
121
431
337










Molecular Recognition Features






MoRF SequenceStartStop




NANANA