<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23231

Description mediator of RNA polymerase II transcription subunit 24 isoform X1
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGTPAAGEKQLAMCLLRLEKTLSSTKNRALLHIAKLEEASLHTSQGLGQGGTRANQPTASWTAIEHSLLKLGEILASLSNPQLRSQAEQCGTLIRSIPTMLAVHSEQLHKTGYPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYCHGDKDFTEDVSCAFEFLLKLTPLLDKADQRCNCDCTKFLLQECSKQGLLSEASVTNLLAKRAADREHAPQLKSGENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTHGNEELAKAASVRALLFDISFLMLCHVAQTYGSEVILSESSTGAQVPFFETWMQTCMPEEGKILNPDHPCFWPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLYSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPSTGVDTMPYWNLLPPKRPIKEVLTDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASSRQKKRHREDIEDYVSLFPLDDMQPSKLMRLLSSNEEDANILSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLSLGRQVAAKAIAAL
Length1008
PositionTail
OrganismVulpes vulpes (Red fox)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Laurasiatheria> Carnivora> Caniformia> Canidae> Vulpes.
Aromaticity0.07
Grand average of hydropathy0.029
Instability index45.89
Isoelectric point6.49
Molecular weight111972.00
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23231
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     585.11|     208|     266|      78|     324|       1
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   44-  279 (295.76/244.55)	EALLEQAMIGPS....PNPLIL..................SYLKYaissqmvsyssVLTAISKF...D.DFSRDL.C.......VQALLDIMDMFCDrLSC.HGKAEECIGlcRALLS..ALHWLLRCTAASAERLREgLEAGTPAAGEKQLAMcLLRLEKTLSST.KNRALLHiAKLEEASLHTSQGLGQGGT.....RANQPTASWTAIEHSLLKLGEiLASLSNPQLrSQAEQCGTLIRSIPTMLAVHSEQlhktGYPTvhAVVLLEGTmnlTGET
  280-  540 (289.35/222.89)	QPLVEQLMMVKRmqhiPTPLFVleiwkacfvgliespegtEELKW.taftflkipqVLVKLKKYchgDkDFTEDVsCafefllkLTPLLDKADQRCN.CDCtKFLLQECSK..QGLLSeaSVTNLLAKRAADREHAPQ.LKSGENANIQPNPGL.ILRAEPTVTNIlKTMDADH.SKSPEGLLGVLGHMLSGKSldlllAAAAATGKLKSFARKFINLNE.FTTHGNEEL.AKAASVRALLFDISFLMLCHVAQ....TYGS..EVILSESS...TGAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     265.63|      81|     194|     566|     734|       2
---------------------------------------------------------------------------
  566-  646 (135.97/217.32)	FWPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFES.IQKITDNIKGKVCSLAV.CAVAWLVAH
  761-  843 (129.65/58.93)	YWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSkWHSLMDPPGTALAKLAVwCALSSYSSH
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23231 with Med24 domain of Kingdom Metazoa
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