<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23222

Description Uncharacterized protein
SequenceMGDVRGNSNSNRPEWLQQYDLIGKIGEGTYGLVFLAKIKANRSKSIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINQADMSLYLAFDYAEHDLYEIIRHHRDKVILSINPYTVKSLLWQLLNGLNYLHSNWIVHRDLKPSNILVMGEGEEHGVVKIADFGLARIYQAPLKPLAENGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGQEVKGTPNPFQLDQLDKIFKVLGHPTPEKWPTLVNLPHWQSDVQRIQGHKYDNPALYSVLHMSPKSPAYDLLSKMLEYDPRKRITATQALEHEYFRMEPLPGRNALVPPQPGEKVVNYPTRPVDTTTDFEGTISLQTSQPVSSGNAASGGMHGPHVMPTRSVPRPMQMVNMPRMQPQGMSAYNLASQAGMSAGMNPGNMPMQRGVAAQAHQQQMRRKDPGMGIPGYPSQQKSRRF
Length467
PositionKinase
OrganismSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Solanales> Solanaceae> Solanoideae> Solaneae> Solanum> Solanum subgen. Lycopersicon.
Aromaticity0.08
Grand average of hydropathy-0.410
Instability index41.03
Isoelectric point9.35
Molecular weight52435.78
Publications
PubMed=22660326

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23222
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.29|      25|      26|     403|     428|       1
---------------------------------------------------------------------------
  371-  386 (21.08/ 7.24)	....QP..VSSGNAAS........GGMHgP
  403-  428 (47.54/28.72)	MPrMQPQGMSAYNLASQAGM...SAGMN.P
  431-  456 (36.68/17.62)	MP.MQ.RGVAAQ..AHQQQMrrkDPGMGiP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.03|      23|      42|     296|     323|       2
---------------------------------------------------------------------------
  296-  323 (29.82/29.99)	PKSPAydllSKMLEYdPRKRITATQALE
  340-  362 (43.21/25.37)	PPQPG....EKVVNY.PTRPVDTTTDFE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.35|      28|      42|     155|     184|       3
---------------------------------------------------------------------------
  155-  184 (44.16/39.46)	LVMGEGEEHGVVKIADFGLarIYQA..PLKPL
  200-  229 (45.19/33.09)	LLLGAKHYTSAVDMWAVGC..IFAEllTLKPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.63|      37|     180|      74|     111|       4
---------------------------------------------------------------------------
   74-  111 (59.69/52.58)	ISH...ENVVKLVNVHINQADMSLYLAFDYAEHDLYEIIrH
  254-  293 (64.94/51.63)	LGHptpEKWPTLVNLPHWQSDVQRIQGHKYDNPALYSVL.H
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23222 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MEPLPGRNALVPPQPGEKVVNYPTRPVDTTTDFEGTISLQTSQPVSSGNAASGGMHGPHVMPTRSVPRPMQMVNMPRMQPQGMSAYNLASQAGMSAGMNPGNMPMQRGVAAQAHQQQMRRKDPGMGIPGYPSQQKSRRF
329
467










Molecular Recognition Features






MoRF SequenceStartStop




1) RKDPGMGIPGYPSQQKSRRF
2) RSKSIAIKKFKQ
448
42
467
53