<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23220
Description |
Mediator of RNA polymerase II transcription subunit 20 |
Sequence | MEEGGLSQSGEEPKSWDELYNVNLMPSEIFLKFRKEIEGYRVGVNLEFYNAPYNEYLAKLVLKPLAPERRWKFIYEPLNHEVRLLSKKIPVTKFLNLQVGVGHSFKLQATGWKWKLTSCFGGDGISSIRNKTSLGLCPGVDFRFGWKADYVFPEVTGQVTLSSFALHFKETHLLNDILLALGTGEPLFNMNSGRLQASLDRDMLLIDIDISQQIIDLLENVEEIIEGENHLSSFHREELKGFSGVSSSGELSGKRKGNLGFNFLRRTFRVLHWQPNAGTTVNSQILTEVSQCVESINGVKEGRWKDTLSFYKPMLRVEQANSLEFPRDFLGISLQEQPNKYYMVIRGQRLIIEAESSIQTIMEKLQSYKTRVALNFEGFQYQLGDFQLRVGKVVTIHSENLRGIVMEMEYLPISSWETSHQIMGEFFDIWQEALGKRSLPGHFVHVEPNFSEYGLSDQYTSQHTAVQYASIMAQMIATAQSSQPMRN |
Length | 487 |
Position | Head |
Organism | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
asterids> lamiids> Solanales> Solanaceae> Solanoideae> Solaneae> Solanum>
Solanum subgen. Lycopersicon.
|
Aromaticity | 0.11 |
Grand average of hydropathy | -0.299 |
Instability index | 43.15 |
Isoelectric point | 6.01 |
Molecular weight | 55655.81 |
Publications | PubMed=22660326
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364152
|
GO - Cellular Component | mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | transcription coactivator activity GO:0003713 IBA:GO_Central
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IBA:GO_Central
|
Interaction
Repeat regions
Repeats |
>MDP23220
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 61.93| 17| 33| 111| 127| 4
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111- 127 (34.72/22.02) GWK..WKLTSCFGGDGISS
145- 163 (27.21/15.77) GWKadYVFPEVTGQVTLSS
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