<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23091

Description mediator of RNA polymerase II transcription subunit 15a-like isoform X2
SequenceMEGNSWRPGQGEPSTADATAGDATAGDWRCQLQHDARQRIVNKIMDTLKRHLPISVPEGLNELQKIAVRFEEKIYTAATSQADYLRKISLKMLSMETKTQHTPPMPNTTIPNQNPTDSGQPLGIPAVNPPTARQQLLPQNLQNNTSTSVQSSANLPPALSSFTGLSQSNISSVGQTSNLQNMPGISQNSVSNSVGQGAAPDIYANAQRQMPGRQHQQQMISQQQQQSQNQLIYHQQFQQQLLKQKLQHPSLLQPHLQQQQPQQSLLQPTQLQSSQQSLMQMSSGLQSGQSTIQQPQPTTMQSAAQPGLQQNQLNSIQQSVPSLLQQHPQSVARQQQQVQPSIHQQTPSLQQQPTPVPQQSNLPLQQQQQQIMGQQANISNLQQAQLLGQQNSIQDMQQPQQQRLPVQQNSLLGMQQPQQMLNQQSISLHQQQQLGPQSTISGLQQQQQQQHQQQQQQHQQQLLGSLPNVSSMQPHQRSMHILQQPKMVTPQQQQTQQTPLSLLQQQGQQSQHQSSQQQLISQFQSQPAQLQQQLAMQQQPNSLQQRLQAPGALLPSQNAIEQQKQFIQAQRVLPEVSSSTSVDSTAQTGHVGVADLQEEIYQKIKSMRDMYFADINELYQRIALKFQQHDGFIPPAKPSEQYEKMKNFKTMLERTLAFLQISKNNIQPGLKDRIPLYEKQIVNILTSNKKKVIPSQSQGQQQFQHPGGLAHSMPQQQPSLVPQLQQHDNHPNQVQQMNLQGSATSMQPSAVTGMQHVSMPLTTNFGVPATQQNITNALQPAANLDSVQGSSFNSLQQGAMGSMPQGGVGSVPNTINAPQQTNANTLSNSSMNTLQPNASLVQPSSNTVQQHYLKQQQQDQQQQLMQSQQMKQQLQQRHVQQMLQQQQKQQLMQSQPSLQQQLHQQQKQQPAQILAHQMPQLHQTNEPNESKVRPGLGIKPGLYQQHFSAGQRPGYYHQLKQGASFPISSPQNLQSSSPQISHHSSPQVDQHNLLASQVKAGTPLQSANSPFVPSPSTPLAPSPIPADSEKLSGLSSVTNAAHVGHQQSALAPPQTQSLAVGTPGISASPFLAEYTSPDGNQATVPSVVPGKTSASERPLERLIKVVKSSTPKALSSAVSDIESVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNFMSQDGSATTKKMKRNTSAMPLNNVSSAGSVNDSFKQSYGLDASELESTATSRVKRQKFEVNHALLEEIREINQQLIDTVVNISEEDADSIAAASDGEGTVIKCSFTAVALSPSLKSQFASSQISPILPLRLLVPANYPKCSPVLLDKLPDESSGESDDLSVKAKSRFSISLRGLSQPMSLGEMARTWDACARKVIAEYAQQTGGGSFSSRYGAWENCVGA
Length1381
PositionTail
OrganismPhoenix dactylifera (Date palm)
KingdomViridiplantae
Lineage
Aromaticity0.03
Grand average of hydropathy-0.723
Instability index76.45
Isoelectric point9.24
Molecular weight151482.71
Publications

Function

Annotated function
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP23091
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            12|    1029.35|      90|      90|     365|     454|       1
---------------------------------------------------------------------------
  100-  166 (57.94/ 7.12)	..QHTPPM.PNTTI.PN..QN.....PTDSG..QPLG..IPAVNP.PtaRQQL.L.......P............QN................LQNN..TSTSVQSSANLPP...AlSSFTGLS.....................
  167-  218 (58.00/ 7.13)	..........QSNI.SS............VG..QTSN..LQNM...................P.........gISQN.......................SVSNSVGQGAAP...D.IYANAQRQMP....G......RQHQ.QQ
  221-  267 (65.46/ 9.12)	SQQQQQ.........S....Q.....NQLIY..H.........QQ.F..QQQL.L.....kqK..........LQHPSLL........QP.................H..............LQQQQ....P......QQSL.LQ
  272-  360 (106.14/19.96)	QSSQQSLM.QMS...SG.LQS.....GQSTI..QQPQ..PTTMQS.A..AQPG.L...................QQNQLNS.....IQQSvPSLLQQhpQSVA.RQQQQVQPsihQ.QTPS.LQQQP....T......PVPQ.QS
  365-  454 (172.20/37.56)	QQQQQQIMGQQANI.SN.LQQ.....AQLLG..QQNS..IQDMQQ.P..QQQR.L.......P..........VQQNSLLG.....MQQP.QQMLNQ..QSISLHQQQQLGP...Q.STISGLQQQQ....Q......QQHQ.QQ
  456-  526 (107.44/20.30)	QQHQQQLLGSLPNV.SS.MQ..........P..HQRS..MHILQQ.P..............................KMVT.....PQQ..QQT.QQ..TPLSLLQQQ..GQ...Q.SQHQSSQQQL....I......SQFQ.SQ
  529-  629 (82.80/13.74)	QLQQQLAMQQQPN...S.LQQrlqapGALLP..SQNA..IEQQKQfI..QAQRvL.......PevssstsvdsTAQTGHVG.....VADL.QEEIYQ..KIKSMRDMYF........ADINELYQRI....A......LKFQ.QH
  637-  730 (93.70/16.64)	KPSEQ..YEKMKNF.KT.MLE.....RTLAF..LQIS..KNNIQP.G..LKDR.I.......P..........LYEKQIVN.....ILTS.NKKKVI..PSQSQGQQQFQHP...G.GLAHSMPQQQ....PslvpqlQQHD.NH
  773-  855 (66.21/ 9.32)	............NI.TNaLQP.....AANLDsvQGSS..FNSLQQ.G..AMGS.M.......P............QGGV.GsvpntINAP.QQ.TNA..NTLSNSSMNTLQP...N.ASLVQPSSNT....V......QQHYlKQ
  856-  906 (88.16/15.17)	QQQDQQ....Q................QLM....QS....QQMKQ.Q..LQQR.........H..........V.................QQMLQQ..Q.....QKQQL.M...Q.SQPS.LQQQ.............LHQ.QQ
  907-  985 (73.46/11.25)	KQQPAQILAHQ.........M.....PQ.LH..QTN........E.P..NESK.VrpglgikP.................G.....LYQQ.HFSAGQ..RPGYYHQLKQ.GA...S.FPISSPQNLQssspQ......ISHH.SS
  987- 1057 (57.87/ 7.10)	QVDQHNLLASQVKAgTP.LQS.....A........NSpfVPSPST.P.lAPSP.I.......P..........ADSEKLSG.....L....SSVTNA..AHVG.HQQSALAP...P.QTQS........................
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP23091 with Med15 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) IPSQSQGQQQFQHPGGLAHSMPQQQPSLVPQLQQHDNHPNQVQQMNLQGSATSMQPSAVTGMQHVSMPLTTNFGVPATQQNITNALQPAANLDSVQGSSFNSLQQGAMGSMPQGGVGSVPNTINAPQQTNANTLSNSSMNTLQPNASLVQPSSNTVQQHYLKQQQQDQQQQLMQSQQMKQQLQQRHVQQMLQQQQKQQLMQSQPSLQQQLHQQQKQQPAQILAHQMPQLHQTNEPNESKVRPGLGIKPGLYQQHFSAGQRPGYYHQLKQGASFPISSPQNLQSSSPQISHHSSPQVDQHNLLASQVKAGTPLQSANSPFVPSPSTPLAPSPIPADSEKLSGLSSVTNAAHVGHQQSALAPPQTQSLAVGT
2) KQKLQHPSLLQPHLQQQQPQQSLLQPTQLQSSQQSLMQMSSGLQSGQSTIQQPQPTTMQSAAQPGLQQNQLNSIQQSVPSLLQQHPQSVARQQQQVQPSIHQQTPSLQQQPTPVPQQSNLPLQQQQQQIMGQQ
3) MEGNSWRPGQGEPSTADATAGDATAGDWRCQL
4) NISSVGQTSNLQNMPGISQNSVSNSVGQGAAPDIYANAQRQMPGRQHQQQMISQQQQ
5) NLQQAQLLGQQNSIQDMQQPQQQRLPVQQNSLLGMQQPQQMLNQQSISLHQQQQLGPQSTISGLQQQQQQQHQQQQQQHQQQLLGSLPNVSSMQPHQRSMHILQQPKMVTPQQQQTQQTPLSLLQQQGQQ
6) PFLAEYTSPDGNQATVPSVVPGKTSASERPLERLIKVV
7) SLKMLSMETKTQHTPPMPNTTIPNQNPTDSGQPLGIPAVNPPTARQQLLPQNLQNNTSTSVQSSANLPPALSSFTGLSQ
693
243
1
169
380
1069
89
1062
375
32
225
509
1106
167

Molecular Recognition Features

MoRF SequenceStartStop
NANANA