<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23085

Description mediator of RNA polymerase II transcription subunit 24 isoform X6
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLTAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGKAEECIGLCRALMSALNWLLRCAAFYTEKFKEMLDQVAAENQLKMCLERLEKILDSMKNRALIHIAKLEETSSWSTVEQSLVKLGENLNNLSSPQLRSQADECISLIKSIPTMLSAHSDQLNKTGFPTIHAVVLLEGTMNLTGETQPLVEQLMMVKRMQRIPSPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYPQGEKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCTSLLLQECSKQGLLSETNMTNLTAKRTADREHAPRLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFTKHISGEGSKAASVRALLFDISFLMLCHVAQTYGSEVILSESSPTGEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLTFESIQKITDNIKGKVCSMAVCAVAWLVAHVRMLGLDEREKSLQMIRQLATPLYSENTLQFYNERSSLSLPCSVVIMSSILEHMCADVLQQTATQIKFPSTGMDTIPYWNLLPPKKPIKEVLTGVFTKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYSVFCLDMQQLTLTLLGHILPNLLTDSSKWHMLMDPPGKALAKLSVWCALSSYSSHNRGQASARQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDANILSSPTDRSMSSSLSASQLHTVSMRDPLNRVLANLFLLISSILGAKTAGTHTQFVQWFMEECVDCLEQGSRGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length995
PositionTail
OrganismAlligator sinensis (Chinese alligator)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Crocodylia> Alligatoridae> Alligatorinae> Alligator.
Aromaticity0.07
Grand average of hydropathy-0.008
Instability index47.38
Isoelectric point6.64
Molecular weight111459.77
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23085
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     176.80|      52|     241|      78|     129|       1
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   78-  129 (91.45/62.24)	VLTAISKFDDFSRDL.C....VQSLLEIMDMFCDR.LSCHGKAEECIGL....C..RALMSALN
  145-  182 (44.99/26.62)	MLDQVAAENQL..KM.C....LERLEKILDSMKNRaLIHIAKLEE...................
  326-  374 (40.36/23.06)	.........DFTEDVnCafefLLKLTPLLDKADQR.CNC.....DCTSLllqeCskQGLLSETN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     357.37|     117|     133|     506|     638|       2
---------------------------------------------------------------------------
  509-  638 (173.78/123.24)	ILSESSP...TGEVPFFETWMQTCMPEEGKILNP..DHPCfrPDSTKvESLVALLNNSSEMKLVQMkWHeaCLSISAAILEIL.....NAWENGVLTFESIQkITDNIkgkvcsMAVCAVAWLVAHV..RMLGLDEREKSLQ
  640-  768 (183.59/93.48)	IRQLATPlysENTLQFYNERSSLSLPCSVVIMSSilEHMC..ADVLQ.QTATQIKFPSTGMDTIPY.WN..LLPPKKPIKEVLtgvftKVLEKGWVDSRSIH.IFDTL......LHMGGVYWFCNNLvkELLKETRKEHTLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.27|      25|     195|     195|     230|       3
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  195-  219 (43.33/18.90)	KLGENLNNLSSPQLRSQADECISLI
  393-  417 (41.94/17.85)	KSAENANIQPNPGLILRAEPTVTNI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23085 with Med24 domain of Kingdom Metazoa
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