<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23074

Description mediator of RNA polymerase II transcription subunit 15a isoform X3
SequenceMQSHQQLLSQNVQNNVASQPNLPPVSSLGQTPNQNIVKNSNIQNIPGPNSVGSSISQNSNLQSMFPGSQRTMPGRQQVGPPQQQLQSQSPQQYLYQQQYLKQKLQQQSQMQQQQQQSLMQPNQLQSSQQSTSIQQSMQSMPQQHSQVMRHQQQQTSMVHQQQTPVTQQTILPAQQQQQLMGPQSNAANMQHSQMLGQQNNVGDIQQPQRMLSQQSNLTSLQQQRQQQLINQQNNPANVHQQQLGNNGPGLQQQHLLGPDSGNADMHTSHHSTHMLQQPKVPMQQQSQQNSLNLLLPHSQQSQPLGSQQQLMPQIHTQSTQLQQQLGLQQQQQPNPSQRDMQQRMQTSGSLLQQNVLDQQKQLYQSQRNLSETSATSLDSTTQSAQPGGNDLQEEIYQKIQAMKESYLPDMNEVYQKVANKLQQHDSHPQQSQTDQIDKLRAYKMLLERMMTFVQIPKSSIVPQYKEKLVPYEKQIINLINQSRPRKSMSSVQVGQIPQTHMSSMQQPQSQVSQLQSHENQMNSQLKSTNLQGSMPTMQQNNIATSQHNPLSGVSAGQQNMMNSMQPGANLDSGQGNSVNSLQHVPMNSIQQTPVSTPQLQTSINSLQSQGGANVSQPNSLQSGSSALQHQLKHQEQQMLQNQQFKQFQHRQMVQRQLFQQQQLHHPTKPQLSAQLQTHQMSQLHQMNDINDLKMRQGIGVKPGVFQHLTSGQHSAYSHQQLKQGNAFPVSSPQHLQAPSPQIQQHSSPQVEQQNHLPSKSKVATPLQSSNSPFVGPTPSPPLAPSPMPGESEKSVPCVSSISNAANIGHQQTGVAVAPPQSLAIGTPGISASPLLAEFSGQDGAHGNALAATSGKSTVTEQPLERLINVVKSISSKALSAAVSDIGSVVSMNDRIAGSAPGNGSRAAVGEDLVSMTNCRLQARNFITQDGTNGIKRMKRYTSAIPLSGVLSAGSMDGSIKQLTASEASDLESTATSSVKKRKIEVNHALLGEIRDINHQLIDTVVDISNVDPTPAVAAAEGAEGILVKCSFIAVALSPSLKSQYASAQMSPIQPLRLLVPANYPNCSPILLDKFPVESSKENEDLSAKAKAKFSISLRSLPQPMSLGDIARTWDVCARSVISEHAQQSGGGSFSSKYGTWENCLTTN
Length1147
PositionTail
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.03
Grand average of hydropathy-0.751
Instability index69.80
Isoelectric point9.27
Molecular weight125740.06
Publications
PubMed=25384727

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23074
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     626.80|      75|      75|     213|     287|       1
---------------------------------------------------------------------------
    2-   86 (54.33/ 6.72)	...........Q....S..HQQLLSQ...NV.Q...N........NVA......S.Q..........P..NLPPvsslgqtpnqnivknsniQNIPGPNSvgssisQNSNLQSmfpgS.QRTMPGRQQVG..PPQ..QQLQ
   87-  145 (83.92/14.23)	SQSP...............QQYLYQQQ..YL.K...Q........KLQ......Q.QsQM.......Q..QQQQ..................QSLMQPNQ..........LQS....S.QQSTS.IQQSMQ.SMP..QQHS
  150-  209 (84.88/14.47)	HQ.........Q....Q..QTSMVHQQ..QT.P.............VT......Q.Q.TI......LP..AQQQ..................QQLMGPQS......NAANMQ........HSQMLGQQNNVgDIQ..QPQR
  213-  287 (141.85/28.94)	QQSN.LTSLQQQ....R..QQQLINQQ..NN.P...A........NVH......Q.Q.QLG..NN.GP..GLQQ..................QHLLGPDS......GNADMHT....S.HHSTHMLQQPKV.PMQ..QQSQ
  299-  361 (77.76/12.67)	QQSQpLGS...........QQQLMPQ....................IHtqstqlQ.Q.QL..........GLQQ..................QQ..QPNP......SQRDMQQ....RmQTSGSLLQQ.NV..LD..QQKQ
  523-  593 (62.65/ 8.83)	SQLK.STNLQGSmptmQ..QNNIATSQ..HN.PlsgV........SAG......Q.Q.NMM..NSmQP..GAN......................LDSGQ......GN.............SVNSLQH..V.PMNsiQQTP
  641-  723 (62.35/ 8.75)	NQ.Q.FKQFQHR....QmvQRQLFQQQqlHH.P...TkpqlsaqlQTH......QmS.QLHqmND.IN..DLKM..................RQGIGVKP......GVFQHLT....SgQHSAYSHQQLK..........Q
  735-  797 (59.05/ 7.92)	LQAP.SPQIQQH....S..SPQ.VEQQ..NHlP...S......ksKVA......T.P.LQS..SN.SPfvGPTP..................SPPLAPSP......MPGE.......S.EKS........V.PC.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.68|      20|      54|     839|     864|       2
---------------------------------------------------------------------------
  839-  858 (33.88/13.43)	SGQD....GAHGNAL.AATSGKSTV
  868-  888 (21.00/12.40)	NVVK....SISSKALsAAVSDIGSV
  890-  913 (25.80/ 7.29)	SMNDriagSAPGNGS.RAAVGEDLV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     171.24|      40|     114|     482|     521|       3
---------------------------------------------------------------------------
  379-  414 (48.54/18.58)	....STTQSAQPGGNDLQEEIYQK......IQAMK.....ESYLPDMNEVY
  415-  456 (47.11/17.78)	QKVANKLQQHDSH.PQ.QSQTDQI....dkLRAYKmllerMMTFV...QIP
  457-  497 (42.03/14.93)	..K.SSI.VPQYK.EKLVPYEKQIinlinqSRPRK.....SMSSVQVGQIP
  498-  521 (33.57/10.19)	QTHMSSMQQPQSQVSQLQSHENQM...........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.86|      19|     234|     810|     838|       5
---------------------------------------------------------------------------
  608-  626 (32.92/ 9.15)	SQGGANVSQPNSLQSGS...SA
  810-  831 (27.94/25.90)	QQTGVAVAPPQSLAIGTpgiSA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23074 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HRQMVQRQLFQQQQLHHPTKPQLSAQLQTHQMSQLHQMNDINDLKMRQGIGVKPGVFQHLTSGQHSAYSHQQLKQGNAFPVSSPQHLQAPSPQIQQHSSPQVEQQNHLPSKSKVATPLQSSNSPFVGPTPSPPLAPSPMPGESEKSVPCVSSISN
2) KSMSSVQVGQIPQTHMSSMQQPQSQVSQLQSHENQMNSQLKSTNLQGSMPTMQQNNIATSQHNPLSGVSAGQQNMMNSMQPGANLDSGQGNSVNSLQHVPMNSIQQTPVSTPQLQTSINSLQSQGGANVSQPNSLQSGSSALQHQLKHQEQQMLQNQQFKQ
3) MQSHQQLLSQNVQNNVASQPNLPPVSSLGQTPNQNIVKNSNIQNIPGPNSVGSSISQNSNLQSMFPGSQRTMPGRQQVGPPQQQLQSQSPQ
4) QQQSQMQQQQQQSLMQPNQLQSSQQSTSIQQSMQSMPQQHSQVMRHQQQQTSMVHQQQTPVTQQTILPAQQQQQLMGPQSNAANMQHSQMLGQQNNVGDIQQPQRMLSQQSNLTSLQQQRQQQLINQQNNPANVHQQQLGNNGPGLQQQHLLGPDSGNADMHTSHHSTHMLQQPKVPMQQQSQQNSLNLLLPHSQQSQPLGSQQQLMPQIHTQSTQLQQQLGLQQQQQPNPSQRDMQQRMQTSGSLLQQNVLDQQKQLYQSQRNLSETSATSLDSTTQSAQPGGNDLQEEIYQKIQ
649
486
1
105
803
646
91
400










Molecular Recognition Features






MoRF SequenceStartStop




1) QQYLYQQQ
91
98