<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23067

Description mediator of RNA polymerase II transcription subunit 16
SequenceMNQIPGTKDPEAEPVAQSLPQPQDTPKPPDKTDSAAVVVAATTTTEEQEVGQEEKRPVPMEEDSLNPATVFSIRLKQPRSNLLHKMSVPELCRNFSAVSWCGKLNAIACAAETCARIPSSTANPPFWIPIHIVIPERPTECAVFNVIADSPRDSVQFIEWSPTSCSRALLIANFHGRVTIWTQPSQGPANLVHDTSCWQREHEWRQDIAVVTKWLSGVSPYRWLSSKSSAPANAKSTFEEKFLSQQSQTSARWPNFLCVCSVFSSGSVQLHWSQWPPSKNDTTPKWFCTSKGLLGCGPSGIMAGDAIITDSGAMHVAGVPIVNPSTIVVWEVTPGPGNGFQVAPKTSTTCAVPPLSPPNWAGFAPLAAYLFSWQDYLLSEAKQGKKQTDQNLLDAVPLYCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRAGSVIAVVIVEGQYMSPYDPDEGPSITGWRVQRWESSLQHVVLHPIFGNPTSSMGGQSPMQTVWQSKVDLSITPTNDFKSHQSPATGMTSDVQKVSESGSDKSKRVNFDPFDLPSDVRTLARVVYSAHGGEIAIAFLRGGVHVFSGPNFTPVDNYQINVGSAIAAPAFSSTSCCSASVWHDSSKNCTILRIIRVLPPSIPISQVKANSSTWERAIAERFWWSLLVGVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSIQHRQQYGPSLDRIKCRLLEGSNAQEVRAMVLDMQARLLLDMLGKGIESALINSSALVPEPWQASGETLSSIDPETMAVEPALIPSIQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGTGSNRNMVASPTQSSATPATSQGGQNGTSSSMGSAQLQTWVQGAIAKISNTTEGGSNPTPNPISGPSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLPRYMGSANRTSDANAQKPQSNTPAPGKVEEIAKPAVVKSDDGQSGRAGAKGAEEVPSGRSRLGSGNAGQGYTFEEVKVLFMMLMDLCRRTAGLQHPLPVSQVGSNNIQVRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDQEDVDCANDAPKLVNSDPLDFSSMEHSDVYYGTHRLWPRKRRMSERDAAFGLNTSVGLGGYLGIMGSRRDVVTATWKTGLEGVWYKCVRCQRQTSAFSSPDAPPSLSPTDREVWWISRWVHGCPMCGGTWARVV
Length1242
PositionTail
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.08
Grand average of hydropathy-0.238
Instability index48.55
Isoelectric point6.34
Molecular weight134660.52
Publications
PubMed=25384727

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23067
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.03|      37|     525|     581|     677|       1
---------------------------------------------------------------------------
  582-  626 (58.48/116.01)	SGPN.FTPVdnyQINVGSAIAAPAFSSTSCCsasvwHDSSKNCTIL
  887-  924 (67.56/17.51)	SGPStFMPI...SINTGTFPGTPAVRLIGDC.....HFLHRLCQLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.85|      23|     525|     650|     677|       2
---------------------------------------------------------------------------
  650-  673 (42.89/25.70)	RAIAERFWWSLLVGVdWWDAVGCT
 1177- 1199 (43.97/21.81)	RDVVTATWKTGLEGV.WYKCVRCQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.79|      10|      15|     172|     181|       3
---------------------------------------------------------------------------
  172-  181 (19.70/11.71)	ANFHGRVTIW
  189-  198 (20.08/12.09)	ANLVHDTSCW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     178.10|      42|     526|     398|     473|       4
---------------------------------------------------------------------------
  334-  362 (46.14/ 8.72)	............PGPGNGFQVAPKTSTTCAVPPLS.PPNWAG
  398-  439 (70.26/71.73)	LYCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRAG
  475-  512 (61.70/19.97)	LQHVVLHPIFGNPTSSMGGQSPMQTVWQSKV.DLSITPT...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.82|      45|     318|     721|     769|       7
---------------------------------------------------------------------------
  721-  769 (69.68/42.73)	GSNAQEVRAMVLDMQARLLLDMlgkgIESALINSSALVPEPWQASGETL
 1038- 1082 (80.14/41.13)	GSNNIQVRLHYIDGNYTVLPEV....VEASLGPHMQNMPRPRGADAAGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.59|      17|      28|      17|      34|       9
---------------------------------------------------------------------------
   17-   34 (28.18/19.30)	QSLPQPQDTPKPPDKtDS
   48-   64 (30.41/16.27)	QEVGQEEKRPVPMEE.DS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23067 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GTGSNRNMVASPTQSSATPATSQGGQNGTSSSMG
2) MGSANRTSDANAQKPQSNTPAPGKVEEIAKPAVVKSDDGQSGRAGAKGAEEVPSGRSRLGS
3) MNQIPGTKDPEAEPVAQSLPQPQDTPKPPDKTDSAAVVVAATTTTEEQEVGQEEKRPVPMEEDS
823
939
1
856
999
64










Molecular Recognition Features






MoRF SequenceStartStop




NANANA