<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23044

Description mediator of RNA polymerase II transcription subunit 33A isoform X3
SequenceMESALEWNDEVREGVLKRLKLWQQCSKKPAAALVTELVEHLNTLGIALPSPELGELLVSQICFDNNHPWMWKFTHHALSSRLLFPLQILSLLASNAIPHRHSHPHSFALFLPLLSQYAFSFQSTPSLSCNRKIVSSVDSALRISETYKVRDLEIGHVFVLFFYEIVISLLDCVLIDWGFQVTFSEKSSLVAAGKGEDCMDIDRNVTQNFEKSEYREQIRKRNSFTALEVLERLTESRKATILLQSVLLNMPEKFNCLQQRLQFLESLELASSELKLVNQVLTKVSANMRGVSHFDYSLSKHRLVGTLINMGSCKIPLKCNYRFCQSPCWVPFDIYMENAMDSRQIPTKSAIDVLTEGIKTLQMLNQASWQETFLALWLSALRLVQRERDPPEGPIPHLVARLCVLLCIVPLAIANVLRDASEHNLSSVQVSMESEYTHEMKSDDSVKRELMSSVQVLGHFSGLLCPPTLVIDAANQAARKAASFIYNSMNGKGESGTGIHANANTKAGGNLRHLIVEACIARNLMDTSVYFWPGYVSTSVLSLSDSSPPEKSPWSMFMEGTPLNNTLINSLTMTPASSLAEIEKLYYIALNGSDVERPAAAKILCGASLGHGWYIQEHVIHHVIKLLASPLPPSHAGSRSLLVDNMPMLCAVLRGASSVDTVHILSLHGVVPTVAAALLPLCEAFGSIKPTSNSTGDESSTTYMAFSLAFLFLIRLWKFCRPPLDLCITELGVAVGGLEYILSLHNHRVMYSQDKRKSNPNLPESASVKPVYIDSFPKLRALYCQYKSCVASALSGISTGNSIHQTANMILSMIYQKITKVGISSSNSSSPTSSNACSSLINSGEDAFQRPMLPGWEVLEALPFVLESILTACAHGRISSRELTTGLRDLVDFLPASLAAIIDYFSSEVTRGVWKLVPMNGTDWPSPAALLPSIELEINAILTHVGVEVPNCSSGGSPVMLPLPMAALVSLSITFKLDKSLEYMHAITGAALENCASGCPWPSMPIIGSLWAQKVRRWHNFIVVSGSRSVFRQNNESVAQLLRSCFTSFLGTLSVSTSKLTSECGVNGLLGSTITAPGAYPVL
Length1083
PositionTail
OrganismVigna radiata var. radiata (Mung bean) (Phaseolus aureus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Vigna.
Aromaticity0.07
Grand average of hydropathy0.119
Instability index45.21
Isoelectric point6.78
Molecular weight118983.18
Publications
PubMed=25384727

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23044
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.47|      19|      25|     796|     814|       1
---------------------------------------------------------------------------
  796-  814 (34.84/19.23)	GISTGNSIHQT.ANMILSMI
  822-  841 (29.63/15.31)	GISSSNSSSPTsSNACSSLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     229.68|      68|      77|     298|     368|       2
---------------------------------------------------------------------------
  298-  368 (113.65/79.40)	LSKHRLVGTLINMGSCKIPlKCNYRFCQSPCWVPFDIymENAMDSRQIPTKSAIDVLTEGIKTLQMLNQAS
  378-  445 (116.02/70.54)	LSALRLVQRERDPPEGPIP.HLVARLCVLLCIVPLAI..ANVLRDASEHNLSSVQVSMESEYTHEMKSDDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.53|      24|      29|     879|     903|       3
---------------------------------------------------------------------------
  879-  903 (36.84/28.80)	SSrELTTGLRDLV.....DF.LPASLAAIID
  906-  935 (34.69/21.61)	SS.EVTRGVWKLVpmngtDWpSPAALLPSIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.92|      16|      29|     740|     755|       4
---------------------------------------------------------------------------
  740-  755 (30.54/24.88)	YILSLHNHRVMYSQDK
  772-  787 (31.38/25.82)	YIDSFPKLRALYCQYK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.60|      25|      29|      58|      86|       5
---------------------------------------------------------------------------
   58-   86 (38.74/39.44)	VSQICFDNNHPwmWKFTH.HALSsrLLFPL
   88-  113 (37.86/22.85)	ILSLLASNAIP..HRHSHpHSFA..LFLPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     159.21|      50|     127|     506|     580|       7
---------------------------------------------------------------------------
  446-  501 (74.08/52.73)	VKRELM.SSVQvlgHFSGLLCPPTLVIDAANQAARKAASFIynsMNGKGESGTGIHA
  520-  570 (85.13/55.74)	IARNLMdTSVY...FWPGYVSTSVLSLSDSSPPEKSPWSMF...MEGTPLNNTLINS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.99|      22|      30|     628|     650|       8
---------------------------------------------------------------------------
  628-  650 (36.92/25.30)	ASPLPPSHAGSRSLLVDN.....MPmLC
  656-  682 (33.07/17.47)	ASSVDTVHILSLHGVVPTvaaalLP.LC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.73|      21|      31|     227|     247|       9
---------------------------------------------------------------------------
  227-  247 (31.19/18.62)	LEVLERLTESRKATILLQSVL
  261-  281 (31.54/18.91)	LQFLESLELASSELKLVNQVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.69|      15|      29|     171|     185|      10
---------------------------------------------------------------------------
  171-  185 (29.45/20.00)	DCVLIDWGFQVTF..SE
  197-  213 (23.24/14.25)	DCMDIDRNVTQNFekSE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23044 with Med33 domain of Kingdom Viridiplantae
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