<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23028

Description mediator of RNA polymerase II transcription subunit 24 isoform X3
SequenceMPLALRWCPTLLSSRLSVSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGSPAAGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILAGLSNPQLRSQAEQCGTLIRSIPTMLSVHTEQPHKTGFPTVHALVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTGELKWTAFTFLKIPQVLVKLKKYCHGDRDFTEDVNSAFEYLLKLTPLLDKADQRCNCDCTNFLLQECGKQGLLSEANVDNLTAKRKADREHAPQQKSGENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSEENTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLHSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPFTGVDTMPYWNLLPPKRPIKEVLMDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDIEDYISLFPLDDMQPSKLMRLLSSNEDDANVLSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLSLGRQVAAKAIAAL
Length899
PositionTail
OrganismTarsius syrichta (Philippine tarsier)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Tarsiiformes> Tarsiidae> Carlito.
Aromaticity0.06
Grand average of hydropathy-0.009
Instability index47.79
Isoelectric point6.63
Molecular weight99879.03
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23028
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.75|      36|     212|       5|      45|       1
---------------------------------------------------------------------------
    5-   45 (58.13/54.46)	LRWC.......PTLLsSRLSVSCHGKAEecigLCRALLSALHWLLRCT
  213-  255 (58.63/38.71)	LKWTaftflkiPQVL.VKLKKYCHGDRD....FTEDVNSAFEYLLKLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.54|      33|      68|     391|     426|       2
---------------------------------------------------------------------------
  391-  426 (51.45/50.08)	ENTKPASVRALLFDISFLMLChvaQTYGSEVILSES
  460-  492 (57.09/45.30)	DSTKVESLVALLNNSSEMKLV...QMKWHEACLSIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.62|      41|     212|     537|     580|       3
---------------------------------------------------------------------------
  537-  580 (61.79/45.70)	HVRMLGLDEREKSlQMIRQLAGPLHSENTLQFYNERVviMSSIL
  753-  793 (68.83/40.97)	YISLFPLDDMQPS.KLMRLLSSNEDDANVLSSPTDRS..MSSSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.98|      19|     258|     584|     602|       4
---------------------------------------------------------------------------
  584-  602 (35.88/23.99)	CADVLQQ..TATQIKF.PFTGV
  841-  862 (28.10/17.25)	CVDCLEQgsRGSILQFmPFTTV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.18|      20|     132|     187|     209|       7
---------------------------------------------------------------------------
  187-  209 (33.18/33.10)	PTplfVLEIWKACFVGLIESPEG
  325-  344 (37.00/25.88)	PT...VTNILKTMDADHSKSPEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.59|      25|     584|     106|     130|       9
---------------------------------------------------------------------------
  106-  130 (43.73/27.14)	LLKLGEILAGL..SNPQLRSQAEQCGT
  691-  717 (42.86/26.45)	LVLLGHILPGLltDSSKWHSLMDPPGT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23028 with Med24 domain of Kingdom Metazoa
Unable to open file!