<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23027

Description mediator of RNA polymerase II transcription subunit 24 isoform X2
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKLFPKGATWDILNLADALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAVSKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGSPAAGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASSWTAIEHSLLKLGEILAGLSNPQLRSQAEQCGTLIRSIPTMLSVHTEQPHKTGFPTVHALVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTGELKWTAFTFLKIPQVLVKLKKYCHGDRDFTEDVNSAFEYLLKLTPLLDKADQRCNCDCTNFLLQECGKQGLLSEANVDNLTAKRKADREHAPQQKSGENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSEENTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLHSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPFTGVDTMPYWNLLPPKRPIKEVLMDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDIEDYISLFPLDDMQPSKLMRLLSSNEDDANVLSSPTDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLSLGRQVAAKAIAAL
Length989
PositionTail
OrganismTarsius syrichta (Philippine tarsier)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Tarsiiformes> Tarsiidae> Carlito.
Aromaticity0.07
Grand average of hydropathy-0.006
Instability index45.48
Isoelectric point6.47
Molecular weight110216.95
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23027
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     223.32|      77|     221|      46|     148|       1
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   46-  126 (121.59/122.58)	LLEQAMIGPS....PNPLIL..................SYLKYAISSqMVSYSSVLTAVSKF...D.DFSRD........LCVQALLDIMDMFCDrLSCHG.KAEECiGlCRALLS
  263-  374 (101.73/54.32)	LVEQLMMVKRmqhiPTPLFVleiwkacfvgliespegtGELKWTAFT.FLKIPQVLVKLKKYchgDrDFTEDvnsafeylLKLTPLLDKADQRCN.CDCTNfLLQEC.G.KQGLLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.54|      33|      69|     481|     516|       2
---------------------------------------------------------------------------
  481-  516 (51.45/41.34)	ENTKPASVRALLFDISFLMLChvaQTYGSEVILSES
  550-  582 (57.09/37.37)	DSTKVESLVALLNNSSEMKLV...QMKWHEACLSIS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.98|      19|     253|     674|     692|       4
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  674-  692 (35.88/23.94)	CADVLQQ..TATQIKF.PFTGV
  931-  952 (28.10/17.19)	CVDCLEQgsRGSILQFmPFTTV
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     214.73|      69|     252|     139|     221|       5
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  139-  221 (102.88/73.00)	AERLREGLEAG.SPAAGekqlamCLQRLEKTLSstknrallHIAKLEEASSWTAIEHSLLKLGEILAGLSNPQLRSQAEQCGTL
  392-  461 (111.85/57.02)	APQQKSGENANiQPNPG......LILRAEPTVT........NILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.08|      29|      73|     756|     784|       6
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  756-  784 (50.11/36.41)	TRKEHTLRA.VELLYSIFCL.DMQQVTLVLL
  830-  860 (43.97/31.00)	TRQKKRHREdIEDYISLFPLdDMQPSKLMRL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23027 with Med24 domain of Kingdom Metazoa
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