<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23026

Description mediator of RNA polymerase II transcription subunit 24 isoform X1
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKLFPKGATWDILNLADALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAVSKFDDFSRDLCVQALLDIMDMFCDRLSCHGKAEECIGLCRALLSALHWLLRCTAASAERLREGLEAGSPAAGEKQLAMCLQRLEKTLSSTKNRALLHIAKLEEASLHTSQGLGQGGTRANQPTASWTAIEHSLLKLGEILAGLSNPQLRSQAEQCGTLIRSIPTMLSVHTEQPHKTGFPTVHALVLLEGTMNLTGETQPLVEQLMMVKRMQHIPTPLFVLEIWKACFVGLIESPEGTGELKWTAFTFLKIPQVLVKLKKYCHGDRDFTEDVNSAFEYLLKLTPLLDKADQRCNCDCTNFLLQECGKQGLLSEANVDNLTAKRKADREHAPQQKSGENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFINLNEFTTYGSEENTKPASVRALLFDISFLMLCHVAQTYGSEVILSESRTGAEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNNSSEMKLVQMKWHEACLSISAAILEILNAWENGVLAFESIQKITDNIKGKVCSLAVCAVAWLVAHVRMLGLDEREKSLQMIRQLAGPLHSENTLQFYNERVVIMSSILEHMCADVLQQTATQIKFPFTGVDTMPYWNLLPPKRPIKEVLMDIFAKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLIKELLKETRKEHTLRAVELLYSIFCLDMQQVTLVLLGHILPGLLTDSSKWHSLMDPPGTALAKLAVWCALSSYSSHKGQASTRQKKRHREDIEDYISLFPLDDMQPSKLMRLLSSNEDDANVLSSPRSPLGSHVPVTHRVMVGEGVLGQQSCVWQTVSSGRSLLPTADRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQGSRGSILQFMPFTTVSELVKVSAMSSPKVVLAITDLSLSLGRQVAAKAIAAL
Length1048
PositionTail
OrganismTarsius syrichta (Philippine tarsier)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Tarsiiformes> Tarsiidae> Carlito.
Aromaticity0.06
Grand average of hydropathy-0.019
Instability index46.01
Isoelectric point6.77
Molecular weight116288.73
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23026
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.54|      33|      69|     500|     535|       1
---------------------------------------------------------------------------
  500-  535 (51.45/38.58)	ENTKPASVRALLFDISFLMLChvaQTYGSEVILSES
  569-  601 (57.09/34.89)	DSTKVESLVALLNNSSEMKLV...QMKWHEACLSIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.32|      43|      71|     887|     931|       2
---------------------------------------------------------------------------
  887-  931 (67.89/53.95)	ANVLSSPRSPLGSHVPVTHRVMVGEGVLGQQSCVWQTvSSGrSLL
  961- 1003 (77.43/51.91)	ANLFLLISSILGSRTAGPHTQFVQWFMEECVDCLEQG.SRG.SIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.08|      29|      73|     775|     803|       3
---------------------------------------------------------------------------
  775-  803 (50.11/32.94)	TRKEHTLRA.VELLYSIFCL.DMQQVTLVLL
  849-  879 (43.97/28.04)	TRQKKRHREdIEDYISLFPLdDMQPSKLMRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.18|      20|     132|     296|     318|       5
---------------------------------------------------------------------------
  296-  318 (33.18/28.12)	PTplfVLEIWKACFVGLIESPEG
  434-  453 (37.00/21.94)	PT...VTNILKTMDADHSKSPEG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23026 with Med24 domain of Kingdom Metazoa
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