<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22992

Description Mediator complex subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINIKKNFPKGASWDYPNLAEALMEQSMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFEDFSRELCVKSLLEIMDMFCHRLSCHGKAEECIGLCRALLGVVVWLLQGCGWYCDNFREMGPSSSTESSLRACQERLHSLMASPKNRALVHIARLEDQGSWNNVEQAILKVTDGLSCIPNQTLRTKVEETLSLIKSVPVMLSIQCESPVDESYPSVHAFIMLEGTMNLTGEIQPLVEQLMMIKRMQRIPTALFVLEIWKACFTGLIESPEGTEELKWTAFTFLKIPQVLLRLKKYTQCEKGQDFTDDVNIAFEYLLKLTPLLDKADQRCNCDCLGMLLQECNKLGLLSEPNTANLTAKRTEDRELAPKLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGSKSASVRALLFDISFLMLCHVVQTYGSEVILSDPSPSGETPFFETWLQTCMPEEGKTLNPDHPCFRPEPGKVETHHSLRNNTGNYRLVKWHEICLSIPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVAHVRVLGRDEREKPQTMIRQLVTPLYGENTLQFYNERVIIMSSIMEHMCADVFQQTATTLRPPVEGQEPIPYRNLLPAKEPIHKALSTQFQVVLRKGWVDSRALHLFESLLNMGGVFWFTNNLVKELLKETRQEWANRAVEILYSIFCLDTQQITLTLLGTILPNLLTDTARWNSLADPPGKALAKLAVWCALSSYSFHNKGASSARQRKRQREDIEDYNSLFPLDDTQPSKLMRLLSSNEDEPVALSSPGDRSISTSLSASQLYTVNMRDPLNRVLANLFLLISSILGSKMAGPHTQFVQSFMEECVECLEQGSRGSILQFMPFTMVSELLKLPALAQPKVVLAITDLTLPLGRRVAAKAISAL
Length987
PositionTail
OrganismCynoglossus semilaevis (Tongue sole)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Carangaria> Pleuronectiformes> Pleuronectoidei> Cynoglossidae> Cynoglossinae> Cynoglossus.
Aromaticity0.07
Grand average of hydropathy-0.067
Instability index47.03
Isoelectric point6.70
Molecular weight110466.04
Publications
PubMed=24487278

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
enteric nervous system development	GO:0048484	IEA:Ensembl
interstitial cell of Cajal differentiation	GO:0061453	IEA:Ensembl
retinal cone cell development	GO:0046549	IEA:Ensembl
thymus development	GO:0048538	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22992
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     888.49|     278|     391|      30|     316|       1
---------------------------------------------------------------------------
   30-  316 (455.04/329.48)	NFPKGASWDYPNLAEALMeqSMIGP..SPNPLILSYLKYAISSQMVSYSSVLTAISKFE.....DFSRELCVKSLL.EI.MDMFCHRLSCHGKaeECIGLCRALLGVV....VWlLQGCgwYCDNFREMGPSSSTESSLRACQERLHSLMASPKNRALV.........HIARLEDQGSWNNVEQAILKVTDGLSCIPNQTLRTKVEETLSLIKSVPVMLSIQCESPVDESYPSVHAFIMLEGTMNLTGEiqPLVEQ.........LMMIKRMQRIPTALFVLEIWKACFTG.LIESPEGTEELKWTAFTFLK.IP.........QVLLR
  322-  411 (24.69/ 6.50)	.............................................................................................................................................................................................................................QCEKGQDFT.DDVN..IAFEYLLKLT....PLLDKadqrcncdcLGML..LQECNKLGLLSEPNTANLTAkRTEDRELAPKLKTAENANIQpNP.........GLILR
  418-  717 (408.76/269.96)	NILKTVDADHSKSPEGLL..GVLGHmlSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPkhisgEGSKSASVRALLfDIsFLMLCHVVQTYGS..EVILSDPSPSGETpffeTW.LQTC..MPEEGKTLNPDHPCFRPEPGKVETHHSLRNNTGNYRLVkwheiclsiPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVAHVRVLGRDEREKP.QTMIRQLVTPLYGENTLQFYNE.....RV.........IIMSSIMEHMCADVF.....QQTATT.LRPPVEGQEPIPYRNLLPAK.EPihkalstqfQVVLR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22992 with Med24 domain of Kingdom Metazoa
Unable to open file!