<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22983

Description Mediator complex subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINIKKNFPKGATWDYLNLAEALMEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFEDFSRELCVKSLLEIMDMFCHRLSCHGKAEECIGLCRALLGVVVWLLQGCAWYCERLRELGPSASTEASLRDCQERLHSLIKSTKNRALVHIARLEEQGSWSNVEQAVLKVTDALSSVPNQTMRTKLEESLSLVKSIPLLLSVQCDPPVRASFPSVHAFIMLEGTMNLTGETQPLVEQLMMIKRMQRIPAPLFVLEIWKACFTGLIESPEGTEELKWTAFTFLKIPQVLLRLKKYPQGDKGQDFMEDVNVAFHYLLKLTPLLDKADQRCNCDCLGMLLQECNKLGLLSDINTTSLTSKREFAPRLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGSKSASVRALLFDISFLMLCHVVQTYGSEVILSDPSPSGETPFFETWLQTCMPEEGKTLNPDHPCFRPEPGKVESLVTLLNNSPEMKLVQVKWHEICLSTPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVAHVRMLGRDEREKPQTMIRQLVTPLYGENTLQFYNERVIIMSSIMEHMCADVFQQTAATLRPPVEGQEPIPYRNLLPAKEPIHKALSTQFQAVLRKGWVDSRALHLFESLLNMGGVFWFTNNLVKELLKETRQEWANRVVELLYSIFCLDTQQITLTLLGTILPNLLTDSAHWQSLADPPGKALAKLSVWCALSSYSSHHKGSFSARQRKRQREDIEDYNSLFPLDDTQPSKLMRLLSSNEDEPAALSSPGDRSMSSSLSASQLHTVNMRDPLNRVLANLFLLISSILGSKMAGPHTQFVQSFMEECVDCLEQGSRGSILQFMPFTMVSELVKLPALAKPKVVLAITDLTLPLGRRVAAKAISAL
Length985
PositionTail
OrganismAmphiprion percula (Orange clownfish) (Lutjanus percula)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Pomacentridae> Amphiprion.
Aromaticity0.07
Grand average of hydropathy-0.033
Instability index44.30
Isoelectric point7.48
Molecular weight110063.94
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
enteric nervous system development	GO:0048484	IEA:Ensembl
interstitial cell of Cajal differentiation	GO:0061453	IEA:Ensembl
retinal cone cell development	GO:0046549	IEA:Ensembl
thymus development	GO:0048538	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22983
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.11|      28|      35|     194|     224|       2
---------------------------------------------------------------------------
  194-  224 (40.82/32.86)	LKV.TD.....ALSSVPNQTMrtkLEESLSLV.KSIPL
  226-  260 (36.29/21.19)	LSVqCDppvraSFPSVHAFIM...LEGTMNLTgETQPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.90|      22|     115|     417|     438|       3
---------------------------------------------------------------------------
  391-  416 (31.15/17.74)	KTAENANIQPNPGLIlraePTVTNIL
  417-  438 (36.74/22.21)	KTVDADHSKSPEGLL....GVLGHML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     357.43|     108|     114|     675|     787|       4
---------------------------------------------------------------------------
  605-  669 (81.52/49.56)	.........................................KGKVCSMA.........ICAVAWLVAH.VRMLGRDEREKPQTMIRQLVTPLYGENTLQFyneRVIIMSSIMEHMC
  675-  787 (172.47/130.36)	QTAATlrPPVEGQEPIPYRNLLPAKEPIHKAlstQFQAVLRKGWVDSRALHLFESLLNMGGVFWFTNNLVKELLKETRQEWANRVVELLYSIFCLDTQQI...TLTLLGTILPNLL
  794-  865 (103.45/66.94)	QSLAD..PPGKALAKLSVWCALSSYSSHHKG...SFSARQRKR..QREDIEDYNSLFPLDDT..QPSKLMR.LLSSNEDEPA..................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      57.64|      12|      35|     141|     152|       5
---------------------------------------------------------------------------
  141-  152 (19.71/10.58)	RLRELGPSASTE
  161-  172 (17.78/ 8.85)	RLHSLIKSTKNR
  179-  190 (20.16/10.98)	RLEEQGSWSNVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.53|      19|     388|      89|     112|       6
---------------------------------------------------------------------------
   94-  112 (36.31/27.13)	VKSLLEIMD..MFCHRLSCHG
  483-  503 (30.21/11.17)	VRALLFDISflMLCHVVQTYG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22983 with Med24 domain of Kingdom Metazoa
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