<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22970

Description Uncharacterized protein
SequenceMYGHQSIPRSVSAGQLNAMMSHPGMVITSQQVMNTPQGVMVSQAGYPQGMINVTQPPSQMMPSQAHIGQQMMNTHVGLVQNLSQSGHMNVQHQQMRPMQQVQMTSQQAYIQQQGMSHPNFVNGQAGSPAVVTGPQGLSQQGTPGRPSSTGGPPSNNPQTPLNAVSTLNPSSQRVSTPATPQQAPSSVQSTGTQDNISTPAVVPPDPVSLSRNLLLRDLRYSLQEWSKTAAEVVRPSTLRQQQDGSGTTTHNPMSVNPQSVNPQSVNPQSVNPLSANPSSVKSLDEPKSVENLEKKFLNPSEAYINSFDYFLGTCDQIENDVMVVQEAQKQSVKFDKMFAGELKIVGEMANVNYSQYAQGYVESTVRVRNAITRTLKNLNATMEKMNAAKIKTALSIEIISFPPNPLRFCRYNKISTKNWQYNAQHKDVNE
Length430
PositionTail
OrganismLitomosoides sigmodontis (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Litomosoides.
Aromaticity0.05
Grand average of hydropathy-0.590
Instability index56.43
Isoelectric point9.21
Molecular weight46959.30
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22970
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     112.19|      19|      19|     251|     269|       1
---------------------------------------------------------------------------
  118-  136 (21.23/ 6.69)	.PNFVNGQAGSP....AVVtGPQG
  151-  171 (25.60/ 9.56)	GPPSNNPQT..PlnavSTL.NPSS
  251-  269 (37.49/17.35)	NPMSVNPQSVNP....QSV.NPQS
  271-  288 (27.87/11.04)	NPLSANPSSVKS....LD..EPKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.07|      17|      19|      34|      52|       2
---------------------------------------------------------------------------
   34-   50 (34.72/19.80)	NTPQGVMVSQAGYPQGM
   55-   71 (32.35/12.56)	QPPSQMMPSQAHIGQQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.81|      13|      19|     174|     186|       3
---------------------------------------------------------------------------
  174-  186 (24.23/11.45)	VSTPATPQQAPSS
  196-  208 (24.58/11.71)	ISTPAVVPPDPVS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.23|      38|      46|     302|     343|       4
---------------------------------------------------------------------------
  302-  343 (55.40/45.32)	AYINSFDYFLGtcdQIENDVMvVQEAQKQSVK.....FDKMFAGELK
  349-  391 (56.83/33.75)	ANVNYSQYAQG...YVESTVR.VRNAITRTLKnlnatMEKMNAAKIK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.63|      15|      20|      79|      95|       5
---------------------------------------------------------------------------
   79-   95 (23.50/18.19)	VQNLSQSGHmnVQHQQM
  101-  115 (28.13/14.81)	VQMTSQQAY..IQQQGM
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22970 with Med29 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AGYPQGMINVTQPPSQMMPSQAHIGQQMMNTHVGLVQNLSQSGHMNVQHQQMRPMQQVQMTSQQAYIQQQGMSHPNFVNGQAGSPAVVTGPQGLSQQGTPGRPSSTGGPPSNNPQTPLNAVSTLNPSSQRVSTPATPQQAPSSVQSTGTQDNISTPAVVPPDPVSLSRNLL
2) WSKTAAEVVRPSTLRQQQDGSGTTTHNPMSVNPQSVNPQSVNPQSVNPLSANPSSVKSLDEPKSVENL
44
225
214
292










Molecular Recognition Features






MoRF SequenceStartStop




1) RNLLLRDLRY
211
220