<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22968

Description Uncharacterized protein
SequenceMVRIKGLLIRYIHKHAVSAYDNPRLEYRNIMDVSDWVKPEVIHVLEQYIQEPTGSIEDLQREIQRITGKNLTANKLRHHLEQFEKETAAYKQHSQDETSEAVPTSSYFQRRAQLPEEIPSSKGAEIGEREEVHAECDTEAVSRTRKVARAVRAVRKITARRREELRILRSYQRHRRRKTRNESTIADKDKDFKATTTVHEEAEEKEATTTPPKFTTKPDGTIFSVASTASTSAELSKTSVISPQEIPSREEECTVSAVEPTASAPTWKEPECTVITTIPPTVSLPTVTKCSGSVSEPNVLFANTPECVELTTKRDDDMSNWNEPECEVLETGSSLFASNRRNTPELEVLSAGPSVLDNCELMSQLKLTAERNIDWCANVTPPPTAGASTAQGSNQYTSGEMQSNISSQQFQSLSTQLDHCLNLLRLLRNEVVSVHTRIMEGGWENDPADGEKTLEERLDFINQIYDNLESHAKQLPTSTPMTVQMERLCRFLHDGQIDPHTSELYDKAQEASTWMETNNQLLQMYAEFLRTVVGNRRRSIMTDRPISYSNYSLNSSPQSIFEQTLTVVLKDPNIKKIGLVGRYLEKSTLSAIVEFKFGQVVDKQYVCLLKMLMVVNSGVPEFVQMIAPHEEWSYLDVGSGQVDIHKESRYLVYRKMSVQANIHLMQTIMPCIDIRNAHTLSYVLNLFAKFSGVFDIKCRACKKIMKDYLPPLIFDLRCPKNALHESCR
Length728
PositionTail
OrganismLitomosoides sigmodontis (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Litomosoides.
Aromaticity0.06
Grand average of hydropathy-0.526
Instability index53.93
Isoelectric point6.02
Molecular weight82659.71
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22968
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.43|      16|      34|     202|     234|       1
---------------------------------------------------------------------------
  206-  222 (25.61/13.86)	EATTTPPKFtTKPDGTI
  259-  274 (29.82/19.10)	EPTASAPTW.KEPECTV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.49|      32|      34|      18|      51|       2
---------------------------------------------------------------------------
   18-   51 (49.27/38.18)	SAYDNPRlEYRNIMDvSDWVKPEVIHVLEQYIQE
   55-   86 (52.22/31.70)	SIEDLQR.EIQRITG.KNLTANKLRHHLEQFEKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     198.42|      54|      63|     383|     436|       3
---------------------------------------------------------------------------
  332-  372 (27.30/ 9.91)	.........GSSLFASN..RRN..TPELE.VLSagpSVLDNC.E.LMSQLkltaeRN.......
  383-  436 (90.41/45.95)	PTAGASTAQGSNQYTSGEMQSNISSQQFQ.SLS...TQLDHCLN.LLRLL.....RNEVVSVHT
  447-  501 (80.71/40.41)	PADGEKTLEERLDFIN.QIYDNLESHAKQlPTS...TPMTVQMErLCRFL.....HDGQIDPHT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.12|      10|      16|     303|     312|       4
---------------------------------------------------------------------------
  303-  312 (19.59/10.50)	NTPECVELTT
  322-  331 (19.53/10.44)	NEPECEVLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     117.17|      30|      63|     106|     137|       5
---------------------------------------------------------------------------
  106-  135 (49.78/27.78)	SY..FQRRAQLPEEIPSSKGAEIGEREEVHAE
  139-  166 (29.22/15.95)	EA..VSRTRKVARAVRAVRKITARRREELR..
  170-  201 (38.17/18.75)	SYqrHRRRKTRNESTIADKDKDFKATTTVHEE
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22968 with Med27 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AELSKTSVISPQEIPSREEECTVSAVEPTASAPTWKEPECTVI
2) ELRILRSYQRHRRRKTRNESTIADKDKDFKATTTVHEEAEEKEATTTPPKFTTKPDGTIFSVASTA
3) QFEKETAAYKQHSQDETSEAVPTSSYFQRRAQLPEEIPSSKGAEIGEREEVHAECDTEAVSRTR
233
164
82
275
229
145










Molecular Recognition Features






MoRF SequenceStartStop




NANANA