<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22943

Description Uncharacterized protein
SequenceMQRYHDASCTSAVNNSSIGGASARDSTRTDSSSLASNFSINPRRLPPLIPYKLKCDKEPLNSRLGPPDFHPQTPNCLEETLTNKYVASGYKEAVVEGLEEGREISHTQAHNFTSPVVKKCKEAIRKCLRAINESRAQKRKAGQVYGVPLSGSLLTKPGVFPEQRPCVEDFKKKWIEGLSQPHKRLRSLADHVPHGYRKKSLLEVLIRNNVPLLRATWFIKVTYLNQVRPSSTSISSGTFDKNQVSRTELWTKDVVDYLQSLLDEYLSRNNPHSAPHSRDRSQQMLYTGSAQHRSDPAPAIIDGEEPSLHFKWWYVARLLHWHHAEGLLLPSVIIDWVLSHLQEKDLLEILQLLLPIIYGVLETVVLSQSYVRTLVGIAVRFIHEPSPGGSDLEDNSRRAYTTSALIEMLRYLILAVPDTFVSLDCFPLPPIVVSYAVNEGAFVSKASEDARKTTDNSAEVADVFRSKGLDAQYQSLSFDRVVSFIQKRADNLAKAASSGYPVHSVAKAVQALDKALSLGDIREAYSYLFENFCERAVDEGWIEEVSPCLRLSLKWLRGVSLSLVRSVFLLCEWATCDYRDFRSAPPRELKFTGRKDFSQVYIVSRLLKLKIQDLQSPSGWKNEKSPRVNSLAKVSNEPNYFGSIPRGNGHGIKSISKTVNRKGTNTSDIFESPGPLHDIIVCWIDQHEVCNGEGLKRLHLLTAELIRSGIFSPQAYVRQLIISGITDTSGPAPDLHRRKRHYRVLKHLPGPFVHDVLEEARVAEGSELLEAMRVYSNERRLLLRRLLCEQYQNSDKSNISLKKLKHHPPVAGKDGASPSSFEQWKNIYPQPSSKVKTEMDVENLKDSISALLQLPTCSTSSETGLDESQGSVKRPAESIGSKMDIVETPGCEDCRKAKRQKLSEERNSCLQGQSPISDDEDTWWVRRGAKSSDSSKADQPPKSSKQVSKGRQKVVRKMQSLAHLAAARIEGSQGASTSHVCDNKVSCPHHRTGIEGDNLKSMDGIGTMRGGDIVSIGKSLKQLRPVEKRTITVWLITVVRQLVEETEKNAAKVSQFNRSFVNVDDRSSIRWKLGEDELSAILYLMDVCSDLVSSAKLLLWLLPKVLSNPNSTIQSGRNIMMPPRNVENHACEVGEAFLLSSLRRYENIIIATDLIPEVLSATMRRVATLLASNERISGSAALIYSRHLLKKYSNMPSVLEWEKSFKTTCDKRLFSELESGRSLDAEFGYPLGVPAGVDLDDFFRQKISGSRLSRVGMSMRDVVQRNIDDAFHYFGKERKLLGAGTAKSPGMEKSDYAYQIAQQIIMGLMDCMRQTGGAAQEGDPSLVSSAVSAIVNNVGPTIAKMPDFSLGSNYSNASAAPGSLILARRILRIHINCLCLLKEALGERQSRVFEVALATEASSALATAFSPGKASRSPFQMSPESHDSSGNISSEILNNSAKATGRGTKSAAAISALLVGAIIHGVTTLERMVTVLRLKEGLDVIQFIRSMKSNSNGNARSFVVFKMDNSIEVYVHWFRLLVGNCRTVSGGLIVELLGEPSLVALSRMQRLLPLSLVFPPAYSIFAFVIWRPFFATREDIHQLNDSLTMAIGDAIKHLPFRDVCLRDSQGLYDLIAADSIDAEFAAMLELNNLDVRFKSKAFVPLRGRLFLNAIIDCKLPLSLITLDDGNRVSGHGGSKVQHAENETKLLDKLVNVLDALQPAKFHWQWVELRLLLNEQALIEKLEAHDMSLADAIRSSSPDPEKAAASENENNFIEIILTRLLVRPDAVPLFSELVHLFGTSLEDSMLLQVKWFLGGHNVLFGRKTIRQRLINIAESKGLSTKAHFWKPWGWSSNGFDPVMDRGDKKKFEVPSLEEGEVVEEGSETKRSGKGSFPIFEYEGSSLFQQNVTERALVELVLPCIDQGSDDSRNTFATDLIKQLNNIEQQINSVTHGTSKQTGTTSSGLEGPANKSNNRKGIRGGSPGLVRRAAATADSTLPSPAALRASMSLRLQLLLRLLPTICTDGEPSGRNMRQMLASVILRLLGSRVVHEDAELSFYPLQSFQSKRELELQLEAASADLSGGSLFDRLLLILHGLLSSSWPSWLKSRSASSSKAVNEFKDFAGFDRELVESLQNDLDRMQLPGKIQLRIQSAMPILLPSVRCLISCQPPPVPTAAVASLQPSIAISGFYNGSNAQKNPAPLARSANNISTKSKPLPLQQDGDMEIDPWTLLEDGTGSGPSSSNISVIGSIDHANLRASSWLKGAVRVRRTDLTYIGAVDDDS
Length2265
PositionKinase
OrganismPopulus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Malpighiales> Salicaceae> Saliceae> Populus.
Aromaticity0.07
Grand average of hydropathy-0.275
Instability index50.92
Isoelectric point8.78
Molecular weight250620.02
Publications
PubMed=16973872

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22943
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     229.90|      74|     104|    1829|    1912|       1
---------------------------------------------------------------------------
 1829- 1912 (108.53/76.02)	KPWGWSSNGFDPVMDRGDKKKfEVPSLEEGeVVEEGSETKRSGKGSfPIFEYEGSSLFQQnvteraLVELVLP..CIDqGSDDSRN
 1938- 2013 (121.37/59.84)	KQTGTTSSGLEGPANKSNNRK.GIRGGSPG.LVRRAAATADSTLPS.PAALRASMSLRLQ......LLLRLLPtiCTD.GEPSGRN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.12|      22|     104|    1534|    1557|       3
---------------------------------------------------------------------------
 1534- 1557 (33.48/24.43)	VELLGEPSLVALsrMQRLLPLSLV
 1643- 1664 (38.64/21.80)	VPLRGRLFLNAI..IDCKLPLSLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     205.88|      70|     302|     374|     451|       4
---------------------------------------------------------------------------
  374-  451 (104.75/94.02)	LVGIAVRFI..HEPSPGgsDledNSRRAYTTSAliEMLRYLILAvPDTFVS.......LDCF.PLPPI...VVSYAVNE...GAFVSKASEDAR
  676-  761 (101.13/66.84)	LHDIIVCWIdqHEVCNG..E...GLKRLHLLTA..ELIRSGIFS.PQAYVRqliisgiTDTSgPAPDLhrrKRHYRVLKhlpGPFVHDVLEEAR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     233.37|      74|      81|     895|     973|       6
---------------------------------------------------------------------------
  867-  920 (62.24/40.11)	.....................ESQGSVKRPAE......SIGSKMD......IVETPGCEdcrkAKRQKLSEERNSCLQGQSPISDDE
  921-  998 (118.71/87.67)	DTWWVRRGaksSDSSKADQPPKSSKQVSKGRQ......KVVRKMQSLAHLAAARIEGSQ...gASTSHVCDNKVSCPHHRTGIEGDN
 1003- 1055 (52.42/29.83)	DGIGTMRG...GDIVSIGKSLKQLRPVEK.RTitvwliTVVRQLVEETEKNAAKV..SQ............................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.04|      40|    1715|       5|      50|       9
---------------------------------------------------------------------------
    5-   50 (65.41/48.15)	HDASCTSAVNNSSiggasaRDSTRTDSSSLASNF.SINPRRL...PPLIP
 1728- 1771 (60.63/33.29)	HDMSLADAIRSSS......PDPEKAAASENENNFiEIILTRLlvrPDAVP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.61|      21|    1715|     121|     141|      13
---------------------------------------------------------------------------
  121-  141 (34.78/24.18)	KEAIRKCLRAINESRAQKRKA
 1805- 1825 (33.83/23.30)	RKTIRQRLINIAESKGLSTKA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.54|      12|      81|     540|     553|      16
---------------------------------------------------------------------------
  540-  553 (19.33/14.68)	GWIEEVSPclRL.SL
  619-  631 (20.21/ 8.25)	GWKNEKSP..RVnSL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22943 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EQQINSVTHGTSKQTGTTSSGLEGPANKSNNRKGIRGGSPGL
2) LSEERNSCLQGQSPISDDEDTWWVRRGAKSSDSSKADQPPKSSKQVSKGRQKVVRK
3) NISLKKLKHHPPVAGKDGASPSSFEQWKNIYP
1926
902
798
1967
957
829










Molecular Recognition Features






MoRF SequenceStartStop




1) LIPYKLK
48
54