<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22921

Description ATP-dependent DNA helicase
SequenceMEHYQATCTPQPAISKFPPITPTADQNSFIRPEEISVPPELCSNCSHGFKLGLCPEAAKHLQEMKDMLIAVSNDLLDNAAELSQAQIDKLRQDRLQLNKQIQQLEKYLRDEERQKSHFSASTLVRNLQYETPQSAACKIDPMRFDAQVHLRNDLNGYEKWNAPSVSFSSIDSFGVSSVPLEREPYIPSFVEVNYIEGSNDPKWSSTNFPWTKKLEANNKKVFGNHSFRPNQREVINATMSGYDVFVLMPTGGGKSLTYQLPALVCPGITLVISPLVSLIQDQIMHLLQANIPAAYLSANMEWTEQQEILRELCSDYCKYRLLYVTPEKVAKSDVLLRNLESLNGRGLLARIVIDEAHCVSQWGHDFRPDYKELGILKKKFEKTPVLALTATATASVKEDVVQALGLVDCIVFRQSFNRPNLWYSVIPKTKKCLEDIDKFIKENHFDECGIIYCLSRMDCEKVAEKLQECGHKTAFYHGNMDAAQRSFVQKQWSKDEINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQRSSCVLYYSYSDYIRVKHMIIQGQAEQSPWTAGCGRNNMKSSDRILEKNTENLLRMVSYSENDVDCRRLLQLLHFGEKFDAGNCGNTCDNCSKIKTLVERDVTESAKQLVELVKLTGQHFSSSHILEVYRGSLSQFVKRHRHENLSLHGAGKHLAKGEASRILRHLVIEDFLAEDVKKSDFYGSVSSVLKVNESKAHKLCSGGQRIVLRFPSSVKASKQGKSEATPAKGSLMSGKLSPPQAGSPAQPQSEVDLNLSAKLFSALRMLRTALLKEAGDGVMAYHIFGNATLQHMSKRIPRTKEELLEINGIGKAKVSKYGDRVLETIESTIREYNKGDRNSSGSNESSDSIKRRRDASKALNGNMEEEDEFTKSTGRSKKRTATRQNKGSEVHNSMEPVSCNQFLDDDLDFKDSYHDLEADA
Length962
PositionUnknown
OrganismPopulus trichocarpa (Western balsam poplar) (Populus balsamifera subsp. trichocarpa)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Malpighiales> Salicaceae> Saliceae> Populus.
Aromaticity0.07
Grand average of hydropathy-0.504
Instability index48.97
Isoelectric point8.01
Molecular weight108208.69
Publications
PubMed=16973872

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22921
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.61|      24|     208|     553|     598|       3
---------------------------------------------------------------------------
  553-  577 (40.97/55.31)	SDY.IRVKHMIiQGQAEQSPWTAG.CG
  602-  627 (34.64/ 9.24)	SENdVDCRRLL.QLLHFGEKFDAGnCG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.81|      18|      18|     432|     449|       4
---------------------------------------------------------------------------
  432-  449 (34.27/24.11)	CLEDIDKFIKENHFDECG
  453-  470 (33.54/23.42)	CLSRMDCEKVAEKLQECG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.64|      18|     134|     215|     233|       5
---------------------------------------------------------------------------
  215-  233 (29.71/19.71)	EANNKKVFGnHSFRPNQRE
  355-  372 (37.93/21.09)	EAHCVSQWG.HDFRPDYKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.86|      27|      30|     806|     834|       9
---------------------------------------------------------------------------
  806-  832 (46.54/42.19)	RMLRT..ALLKEAGDGVMAYHIFGNATLQ
  837-  865 (40.32/26.64)	RIPRTkeELLEINGIGKAKVSKYGDRVLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.62|      17|      17|     883|     899|      11
---------------------------------------------------------------------------
  883-  899 (27.61/15.80)	GSNESSDSIKRRRDASK
  903-  919 (29.00/16.94)	GNMEEEDEFTKSTGRSK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22921 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IESTIREYNKGDRNSSGSNESSDSIKRRRDASKALNGNMEEEDEFTKSTGRSKKRTATRQNKGSEVHNSMEPVSCNQ
2) SKQGKSEATPAKGSLMSGKLSPPQAGSPAQPQS
867
759
943
791










Molecular Recognition Features






MoRF SequenceStartStop




NANANA