<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22903

Description Mediator of RNA polymerase II transcription subunit 16 isoform X1
SequenceMDYVYLVDLKDFLTKTEINPDSDYFSCVVSSLNVVALSANCCVYILPLEKPNELKPVTLSKSPCIHLAWSHDGQYLLSFFKNGQLNIFKIKTCSLDSIKNVFSSEFNFNDILAIKAFSKASKICFSHDKKDPCSYFEKFCHKKIGLMNTDLGIMHDGFLILTKTGTLHFIITESDGTKNQFKKLKFDLNLNDLLNNGSSGEQIKFDLGDFYFEEDGSINVILSHTDTRPVFLFRIDAKYSMDELYIVGTTNLIGSLNLPIDLSDLKTHLVFTSHESAQSFCVAFKSNTIQFYKLDQNFSMIRTIQCPSTLTGLSVPKSYTLYKDLVENRLLTDAVFIIASYQNGSQGFIDILTFNQINIPTELTSIRNDLHNFELSERSNLSKKIKFPHEFLIQVDQSCSGLIGVGLTNLSRLAVCRNPFFINDQNIVLNHLFDLYEYTIFSGHDYWDLMMTTNPKFVDNLIESLEDKFNNHLSPSMQKIYFSRHHSLMFSLYKRSRNHNYFRSQDILIKLILNRIMSIISFSVQFSLNVDQMKSSMGSASSLSTSQLVSVVDTLNQPTAMFSSSILNQTQFKNNLLDFLNEVLKVKPDAKTNFGDLKQLALNDIVAAILSRKNYQLCVNQQLKHVLQWVIDLALYLINVVQSFKFNHSPSHFGLSLLNDLWFLNEVRKVIVVVKLMISYNGQHQTNASHLLINSVPVLPVKSSMQKDFLSELFKLYSNIIQRIIEGSTLNDESVIDSCLTIQAETIIRPMDELLFKLKFSWLGSSSDLWTNTIKFPVDHLFDNEKHRQIYPLFDIIRLIQFSRSPITKQCIRCGNYTEANSNQTQPNTKKNCIFLQDSSGEKCFCGGYFVLSN
Length854
PositionTail
OrganismBrachionus plicatilis (Marine rotifer) (Brachionus muelleri)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Gnathifera> Rotifera> Eurotatoria> Monogononta> Pseudotrocha> Ploima> Brachionidae> Brachionus.
Aromaticity0.11
Grand average of hydropathy-0.058
Instability index29.17
Isoelectric point6.91
Molecular weight97618.06
Publications
PubMed=30375419

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22903
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     275.86|      72|      79|      76|     150|       1
---------------------------------------------------------------------------
   27-   73 (57.54/31.12)	.................CVVSSLNVVALS...ANCCVYILPLEKPNELKPVTLS...KSPCIHL.AWSHDG.......
   76-  150 (115.15/84.14)	LLSFFKNGQLNiFkIKTCSLDSIKNVFSS...EFNFNDILAIKAFSKASKICFShDKKDPCSYFEKFCHKKIGLMNTD
  158-  226 (103.17/62.96)	FLILTKTGTLH.F.IITES.DGTKNQFKKlkfDLNLNDLL..NNGSSGEQIKF..DLGD..FYFEEDGSINVILSHTD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     120.92|      33|      38|     413|     450|       2
---------------------------------------------------------------------------
  416-  444 (47.36/35.61)	...........CRNPFFIND.....QNI....VLNHLFDLYEYTI.FSGH
  446-  485 (43.33/37.72)	YwDLM.....mTTNPKFVDNlieslEDK....FNNHLSPSMQKIY.FSRH
  486-  527 (30.22/13.56)	H.SLMfslykrSRNHNYFRS.....QDIliklILNRIMSIISFSVqFS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.12|      21|     198|     339|     377|       3
---------------------------------------------------------------------------
  353-  377 (29.92/45.17)	TFNQiniPTEL........TSIRNDLHNFeLSE
  554-  582 (32.20/ 9.15)	TLNQ...PTAMfsssilnqTQFKNNLLDF.LNE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22903 with Med16 domain of Kingdom Metazoa
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