<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22901

Description Mediator of RNA polymerase II transcription subunit 27
SequenceMSTHIPIQNPMQRQGPGNMMPVQQGAGFANQSANQQQSTASALPHHSSQPVIDPDLKKIQDMYEAINLVENIKQDIHAILENVGKANSANNYANILNINKNIVDHQEVPKTAPVVAAVTGSIGTPLSVSNAYNQNPAANIQAETEQSSTNDNCEKNQNLNEDEAEFFEKTDNKFMQSKIIDINKSINDLDKIIKELQPITMLIPFQSSTPVQMWQSDFFSVLLDQQFEEKTTANSSKLLNKYRYLSKLQENFNLTSLGVYKRFQQSYSELKSAKPKPINRIFKKEELEKFISNLLGSPEFKVVAAQKSEHQFVLDIIMPQNFKFVFLFFDANVEKLQVRPLDSRILKIYANNKPSDEICFYDFDHKNKSLVFERLEKNCIIAWTFFKTEFGMNHLKNLMKWVKNFKDLFNAKCTRCEKHLLNGLPPTWRDLKTYQPYHDECRIF
Length444
PositionTail
OrganismBrachionus plicatilis (Marine rotifer) (Brachionus muelleri)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Gnathifera> Rotifera> Eurotatoria> Monogononta> Pseudotrocha> Ploima> Brachionidae> Brachionus.
Aromaticity0.10
Grand average of hydropathy-0.542
Instability index47.45
Isoelectric point7.61
Molecular weight51087.59
Publications
PubMed=30375419

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22901
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     177.50|      53|     159|     230|     282|       1
---------------------------------------------------------------------------
  230-  282 (87.72/57.03)	KTTANSSKLLNKYRYLSKLQENFNLTSLGVYKR....FQQSYSELKSAKP.KPINRIF
  387-  444 (89.78/58.53)	KTEFGMNHLKNLMKWVKNFKDLFNAKCTRCEKHllngLPPTWRDLKTYQPyHDECRIF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.74|      31|      82|      95|     125|       2
---------------------------------------------------------------------------
   95-  125 (52.61/34.88)	ILNINKNIVDHQEVPKT.APVVAAVTGSIGTP
  179-  210 (49.13/32.13)	IIDINKSINDLDKIIKElQPITMLIPFQSSTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.40|      41|      43|     286|     326|       4
---------------------------------------------------------------------------
  286-  326 (68.26/48.59)	ELEKFISNLLGSPEFKVVAAQKSEHQFVLDIIMPQNFKFVF
  332-  372 (70.14/50.13)	NVEKLQVRPLDSRILKIYANNKPSDEICFYDFDHKNKSLVF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22901 with Med27 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSTHIPIQNPMQRQGPGNMMPVQQGAGFANQSANQQQSTASALPHHSSQPVIDPDL
2) NQNPAANIQAETEQSSTNDNCEKNQNLNED
1
133
56
162










Molecular Recognition Features






MoRF SequenceStartStop




NANANA