<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22898

Description Uncharacterized protein
SequenceMVTGIANNLKGEKASRIIQMQHTQSHGCVVCGSSQNGDSILLCDGCDGEYHTYCLVPPLTEIPAGDFYCKTCIDTNVAKQHMATADTIVAASGTTAIAPDTSPSQAEDPSTSADTVTNTPDILMKDSKYRGVSKVSMKGVKKPFVAKLWQGSKYLQLGTFGSEIEAAHAYDKAALMHYGTSAQLNFPHLHDSFVQPEVAFSVRQQTPNAATETSVTSSPVRPSSVDYSTSPGRGRGRCRGRGRGRGRGKRLHGSPDVHATDVQFEAKRRKTEFSEKALSVSAKKYLGVQVHRVYAHAQINVNGKVVNLGTFSTAEEAAMAYDKAALKYFGGPTDCSDAHPDEIVLNFPKKRDVLLKQLLEEEKQTLAQQEAKVGGSSYASRSVQNAKYNLLIMKLNAWLSKLQRSVKMVEASQRVQWGLHSMSAKSNNEEDSTQMDDATSVLSLVKTEIFGPGPTIKKEFTTRDQKLRQNNKEIQNAVLMMIEELKLYVADAPVDPLFQPPPRCAPILDLLSTSRHLKLISAINDLAHLKVRVDGRDPNSVVDGRFESKLRAVVDYRARLQMSSSNEKQKLAHFMRDVETGSSPGMNSTSPVIVGGNTVATNAERRLHTLKEFGLLRNAKYVKRKVLLSKPGTQISGGQIDSSKHLIQANEEIKEEEPDGSLGEAELVTATDVIMEVTGAEKQEEEMIGCSAVIALAEAGKDEAGAASVTVCKSAKLDNNMDVEESGTDTDPVSQVANMNRSTEKETNKFADFLETAVDKAETEEEKPKDDKVETSKPEKETIGTEKSKKVKAEKHEDESEARKSEKADTKYVDESAESENITDDNYQEDPSSDSKAACFEGEPSMAVCDDDVSRKSASDASSSSTAIVSGDEFEWEFYLAIRTEDKWRLLPLSSKTRVTSEIVDDVNLTENEVSKMEVSLEEVCSSSLTDEKTAWMEHLRQLHVEEGQVRQHIQRETNRQHTLEGIIKIEQERLNENSAVYRETMDRLDVETMLALKNHERVGQDAQLVELMHHSFDPILHDLLDKCEGALLNCFQKLSRRFEDFAQEFEYYRNSLLTLTQSPGKELTTGDGQASPVDAAASNLDDNSAVVKRENIARVADTISTVSDVLEHADGSEVISTEESDGFDDLNNSSGLRQAYVTFYMGEMKALWKERSSSLEMVQVIQRSLLNYTTGIATPYENATLLVETALPSEVPESTDVEMKVESGNAEKTTKESIAIAPETEHTSETSFCVAEGNAIDTQNETERGPNENAMQSVDTKAKTDNSPVLVAQGLVTLKMKSAPVSSEVNVKIEPQLASGKFRREQELREAVVSCLTQWQSIQWPTELNSTFLTPTSVALSNLSPKVKSEQITSQYLAVTHEDNTESYSVMEELKRVMIDLTQDQAIPVPPPVKPTTLVMYHPVFFNHQTPKNHPECPERMERVVNILNSLAKKHQETVKLDRLSMSPEELCPPETTLLMVHSPTYLRQLMERSIEAGSQSASSPTASSPSSRALVFESDSGIREEPKPKRGGRKNNGRPPLVGAFGAASLEQNGVELDTFVSSKSWDVARAAAGTVCLAVDRVVRKEYHNAVCLVRPPGHHVGRHGRTEKAPSSGFCLLNNVVIGATHARLYPWVHKVAVLDWDIHHGNGTEELLKDDPDAFFASIHLYSSGKYFPGTGKSCETGNRVNVALENTGAGSGSQAFRSALELKVLPAMRAFQPDIIFISAGFDGHRDDILGGVAAVNNPNVPAGYVEEDFAWATLETLKLAAEVCDGRVISVLEGGYDVRRETNSLAKSVAAHVAAISAYETARRKTGDNFIADVEMKEGAGDTTATTSVRASSIKMDQYIKKERGVSLLEKLLSADVTNENAIIVDDEENEEEGDSEGTHEVHHDGDGDIEDEEDSGEEEEDDDVEMEEAELDSEEPYGHIEKSRQGTPLAMELDDSDPFYLADILLGRVGVLRSTAESIILELCEAKTKLEPGHASDDALRLAIKNKLERVQTNLKLLRKLVPEFDGKTKPIESVNQTHRNLLLEYHWKNQVQDMGCKAQTVYLEQLCSTFPRLEMLSDVRCPPTPCSLFVPKSHKRSRVFDPFGEKQPATLNEMMDYMMAKNRKLKFFKHAETTRGGRRVIKSIKCEINKEMTVHLSFCPPIPENGPNGETGVAASPMTPSTPTSPAFGGGRLRSTRNKHKKLQQQLVKKKKGDMLTKAKLAAEEATKMEMEELKQRITEAREASKEQEQARAAGIQVTKYIQRLSIFPYNEDTPLGAWSESSHNLFRLVTLHSRKALDHFRKQHPETCFYHLFTWLGFYDKIYQTPCSFCKKLLTKESEEWAYVPPSFRDYANGQAFHSKCLPIELTER
Length2343
PositionTail
OrganismPeronospora effusa
KingdomOomycetes
LineageEukaryota> Sar> Stramenopiles> Oomycota> Peronosporales> Peronosporaceae> Peronospora.
Aromaticity0.06
Grand average of hydropathy-0.549
Instability index44.68
Isoelectric point5.41
Molecular weight259307.23
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
DNA-binding transcription factor activity	GO:0003700	IEA:InterPro
metal ion binding	GO:0046872	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22898
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.92|      15|      17|     755|     769|       1
---------------------------------------------------------------------------
  755-  769 (25.19/15.64)	ETAVDKAET.EEEKPK
  774-  789 (20.73/11.27)	ETSKPEKETiGTEKSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.17|      14|      17|     941|     957|       2
---------------------------------------------------------------------------
  941-  957 (16.28/22.08)	RQlHVEEGQVRqhIQRE
  960-  973 (24.89/15.94)	RQ.HTLEGIIK..IEQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.15|      19|      19|    1891|    1909|       3
---------------------------------------------------------------------------
 1891- 1909 (30.81/17.62)	EEDDDVEMEEAELDSEEPY
 1913- 1931 (31.34/18.07)	EKSRQGTPLAMELDDSDPF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.01|      13|      18|    1239|    1255|       4
---------------------------------------------------------------------------
 1239- 1251 (22.96/17.45)	NAIDTQNETERGP
 1257- 1269 (22.05/ 6.19)	QSVDTKAKTDNSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.89|      18|      18|     895|     912|       5
---------------------------------------------------------------------------
  895-  912 (29.09/24.25)	SKTRVTSEIVDDVNLTEN
  915-  932 (29.80/25.09)	SKMEVSLEEVCSSSLTDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.31|      18|      18|     657|     674|       6
---------------------------------------------------------------------------
  657-  674 (29.05/17.49)	EPDGS.LGEAELVTATDVI
  676-  694 (25.26/14.18)	EVTGAeKQEEEMIGCSAVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.57|      16|      19|    2040|    2055|       7
---------------------------------------------------------------------------
 2040- 2055 (32.28/21.01)	CSTF.PRLEMLSDVRCP
 2059- 2075 (27.30/16.52)	CSLFvPKSHKRSRVFDP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.12|      18|      20|    1396|    1415|       8
---------------------------------------------------------------------------
 1396- 1415 (31.16/29.00)	PTTlvMYHPVFFNHQTPKNH
 1419- 1436 (29.95/20.39)	PER..MERVVNILNSLAKKH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.54|      12|      19|    1558|    1569|      10
---------------------------------------------------------------------------
 1558- 1569 (21.60/14.45)	VCLA......VDRVVRKE
 1574- 1591 (16.93/ 9.57)	VCLVrppghhVGRHGRTE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.97|      25|    1123|     197|     231|      12
---------------------------------------------------------------------------
  202-  231 (36.86/39.40)	VRQQTPNAatETSVTSSPVRPSSvdySTSP
 2135- 2159 (50.12/24.23)	IPENGPNG..ETGVAASPMTPST...PTSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.69|      12|      19|    1991|    2002|      15
---------------------------------------------------------------------------
 1991- 2002 (20.80/14.59)	RKLVPEFDGKTK
 2012- 2023 (22.89/16.97)	RNLLLEYHWKNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.00|      16|      23|     819|     834|      16
---------------------------------------------------------------------------
  819-  834 (28.34/17.65)	SE..........NITDDNYQEDPSSD
  835-  860 (18.66/ 8.83)	SKaacfegepsmAVCDDDVSRKSASD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.70|      17|      23|    1754|    1774|      17
---------------------------------------------------------------------------
 1754- 1773 (21.46/24.50)	VCdGRVISVleGGYD.VRRET
 1780- 1797 (23.24/ 8.30)	VA.AHVAAI..SAYEtARRKT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.34|      15|     602|    1201|    1215|      18
---------------------------------------------------------------------------
 1201- 1215 (26.43/15.02)	DVEMKVESGNAEKTT
 1804- 1818 (26.92/15.44)	DVEMKEGAGDTTATT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22898 with Med27 domain of Kingdom Oomycetes


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ASVTVCKSAKLDNNMDVEESGTDTDPVSQVANMNRSTEKETNKFADFLETAVDKAETEEEKPKDDKVETSKPEKETIGTEKSKKVKAEKHEDESEARKSEKADTKYVDESAESENITDDNYQEDPSSDSKAACFEGEPSMAVCDDDVSRKSASDASSSST
2) FSVRQQTPNAATETSVTSSPVRPSSVDYSTSPGRGRGRCRGRGRGRGRGKRLHGSPDVHATDVQFEA
3) GQIDSSKHLIQANEEIKEEEPDGSLGEAELV
4) LMERSIEAGSQSASSPTASSPSSRALVFESDSGIREEPKPKRGGRKNNGRPPLVGAF
5) LVETALPSEVPESTDVEMKVESGNAEKTTKESIAIAPETEHTS
6) NENAIIVDDEENEEEGDSEGTHEVHHDGDGDIEDEEDSGEEEEDDDVEMEEAELDSEEPYGHIEKSRQGTPLAMEL
7) QKLAHFMRDVETGSSPGMNSTSPVIVGGNT
8) SFCPPIPENGPNGETGVAASPMTPSTPTSPAFGGGRLRSTRNKHKKLQQQLVKK
9) TSFCVAEGNAIDTQNETERGPNENAMQSVDTKAKTDN
707
200
638
1471
1187
1850
569
2130
1231
866
266
668
1527
1229
1925
598
2183
1267










Molecular Recognition Features






MoRF SequenceStartStop




NANANA