<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22892
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MDLIYDVVWSTSKPVKSNPCGKVVVAWSCRNLIAFSTGYRKLDLNEEHNPSGTNGQNKRSQVTNGINILDPDCPWDVCSFSSGHEGLIQTLSWDGTGSRLLSTDLVGNYMVNDWECIRTIDVGEGERLVAISWIDTGIKNLFSMSEDPQHSFMQKNLSDRFKTNRSKPPLVEIGGMRAKDGWVAISETGLICVTTIKPEVQVTRKCLAQVRSRVAVADLAFSSKGKVIVVANDGEPCSAVQFFRVSLSGGPGTDDCQIQSDPLPCLFPHSPTEPKNYPEYRVKNIQFLSKHSGEALLVCTTGPFGSCIKRWEMKKEVIQLHERFQLEITHPRGGNYSVYEWKNVNTYDDSAKIVCLCLPRIPTPKVDISPMSNLMTYPASFLMVQYDDDRLQMLNCVGLVPSGSFRTKMKPSADSDLGTAPKRARLSVASYNTGCLGAICYSPCCCCMVGVTMAGDIRLLKLHHLGDSMAGIRLKRSLSDLLHYCLLTGWEWWDVLMAAHLGTPPEISSTLDLEVDKVLQVLDTKELTLDSTTALSMFPLIQWLTDLAMFVVVAYTSQQNKESAPGVSLIRDTSTLGTLREMLVLIRLWGQTTPAVLPSITPSADKNESLALLFKILTKIWLLSRQASSDEPDIHVDDRLAAPLIPNSMSLQNMQIGNLSRGVSGKAVSGPIRPSVYQFGSPPVAHQYHQIFHPFASAIFPMPADGSHVMDIVRRVYLDKSPETKLKQCTRCNCVSLVEGISDHAAARAWDQRWMRACVCGGSWRKLPYKEQQTVVTAATTSSSSSSDATASASVSSQ |
Length | 798 |
Position | Tail |
Organism | Pocillopora damicornis |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Cnidaria> Anthozoa> Hexacorallia> Scleractinia>
Astrocoeniina> Pocilloporidae> Pocillopora.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.129 |
Instability index | 37.72 |
Isoelectric point | 7.44 |
Molecular weight | 87936.02 |
Publications | PubMed=30382153
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Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
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GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP22892
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 259.70| 77| 369| 247| 325| 2
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247- 325 (135.23/101.39) LSGGPGTDDCQIQSD...PLPcLFPHSpTEPK..NYPEYRVKNIQF..LSKH.SGEALLVCTTGPFGSCIKRWEMKKEVIQLHERFQ
329- 359 (23.59/ 8.50) ............................THPRggNYSVYEWKNV.....NTY.DDSAKIVCLCLP......................
623- 693 (100.88/65.59) LSRQASSDEPDIHVDdrlAAP.LIPNS...........MSLQNMQIgnLSRGvSGKAV....SGPIRPSVYQFGSPPVAHQYHQIFH
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