<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22889

Description RNA polymerase II holoenzyme cyclin-like subunit
SequenceMLKCSDASATIAFSLAGAPHQPPEVPIGGGGRQPRLDETGLLPSSTCLVHLRSASQLVSFSILRLSQLHRKDALTGASREAMSANYWESTQRRFWQFTKDQLVTMRQKLEDDNAELVRMFPLPQQRHLNIYFNQQLIRLAKRLTIRQQSMATAQVYMKRFYSKVEIRRTNPYLVIATAIYLACKMEESPQHIRLIVTEARQMWGDLVAIDTSKLGECEFFMISEMRSQLIVHQPYRSISALRSELSLVEDEVQLARSVINDHYMTDLPLLYAPHIIALVAILLALVLRPNNSAPGQSSGSAAAAGLAAAQQALLRAQGQSSQTGFSDASAAEPKEKQQQARVSRVQRFAAWLVESNVEIASMVDATQEIISFYECYEQYNDKLTREQINRFVKARGLDK
Length399
PositionKinase
OrganismFusarium kuroshium
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Nectriaceae> Fusarium> Fusarium solani species complex.
Aromaticity0.07
Grand average of hydropathy-0.220
Instability index61.96
Isoelectric point9.02
Molecular weight44919.01
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22889
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.42|      24|      27|     278|     302|       1
---------------------------------------------------------------------------
  278-  302 (36.92/25.32)	LVAILLALvLRP..NNSAPGQSSGSAA
  306-  331 (35.50/19.93)	LAAAQQAL.LRAqgQSSQTGFSDASAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.28|      18|      23|     145|     167|       4
---------------------------------------------------------------------------
  145-  167 (22.62/28.74)	IrqqsMATAqVYM..KRFYSKVEIR
  174-  193 (27.66/16.95)	V....IATA.IYLacKMEESPQHIR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.10|      21|      32|     194|     218|       6
---------------------------------------------------------------------------
  194-  218 (28.09/28.15)	LIVteaRQMWGDLVAIdTSKLGECE
  229-  249 (35.01/20.81)	LIV...HQPYRSISAL.RSELSLVE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22889 with CycC domain of Kingdom Fungi
Unable to open file!