<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22870

Description Mediator of RNA polymerase II transcription subunit 16 isoform X2
SequenceMTSSAPPNPSPVPVPLPVPTPTPTANGTASSPKDQQQQQQQQPPPPQQQQQAGGQEELAPADGGGAEAAEAGVVAGVASEAMEVDGGPGSGDAEAGGVAGGGGGGGAGGGGQQASPATVFRIRLKQSPASLRHKMRVPELCRNFSAVAWCGKLNAIACASETCARIPSSNSSPPFWIPIHILNPERPTECSVFNVKADSPRDFVQFIEWSPRSCPRALLVANFHGRITIWTQPNKGPVNLVRDASSWQCEHEWRQDLSVVTKWLSGVSPYRWLPASSTSSNLKTFEEKFLTQQPQSSVFSSGSVQLHWSQWPSQNSAQPRWFSTSKGLLGAGPSGIMAADAIVTESGALHVAGVPLVNPSTVVVWEVMPGLGNGIQATAKINATSSVPPSLNPPSWPGFAPLAAYLFSLQDYLVSEGAQTKKQTENETTEAASIHCCPVSNFSAYVSPEAAAQSATTTTWGSGVTSVAFDPTRGGSVITVVIVEGQYMSPYDPDEGPSITGWRVQCWESSRQPVVLHPIFGSPTSFGGQPPMQIVWSTRVNKSIPPTEDLKNPQTYVPMPTTSDERSSSECSVDRANRLSFDPYDLPNDVRQLAQIVYSAHGGEVAVAFLRGGVHIFSGPDFDKVDSYHVNVGSAIAPPAFSSSSCCLASVWHDTLKDRTILKIIRVLPPANLSTQTKVNSAAWERAIADRFWWSLLAGVDWWDAVGCTQSAAEDGIVSLNSVIAFLDADFHSLPTMQQRQQHCPNLDRIKCRLLEGTNAQDVRALVLDMQARLLLDMLGKGIESALINPSTLLPEPWQASSDMLSSIEPDKMTVEPALLPNIQGYVDAVLDLASHFITRLRRYASFCRTLASHVGPSSTTGTSRNMVTSPTNSSPSPSNNQGNQGGATSAPGNSQMQEWVQGAIAKISNNSDGAATTTPNPMSGRSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCLLFRRRQSPRLLANAQKNQDSAIQKIQHMMNAKTEDSSTTVRSGLGAAKIEDGQAMRGGQFALGAKGPEENPIGKSVRIGSGNAGQGYTSDEVKVLFLILVDLCRRTSTLPHPLPASQVGSSNIIIRLHYIDGNYTVLPEVVEASLGPHMQNMPRPRGADAAGLLLRELELQPPAEEWHRRNMFGGPWSEPDDFGPLDNMPHQKVSGSINPHLSDMEEDYGNSLGVQSLWPRKRRLSERDAAFGLKTSVGLGGYLGVMGSRRDVVTAVWRTGLDGEWYKMPKALITLQLEADRVGAVGFISTTTGFNSAAASARTSEQKPRPDLCPPAPPSPAMASPYAGGVQSPSPAAAAQQQQQNHSLAFRVMRLSRPSLQPDPATLLRFDPRDVFLPEDALTGPDPSAAADFLHGVLHPPDPTATVPGEFTFRDRFLLRDPADALALPGLLVLPQSFGFASSLPKSRFRSVPCCSRAIYLGETFCSYISINNSSSFEARDVVIKAEIQTERQRILLLDTSKSPVESIRSGGRYDFIVEHDVKELGAHTLVCTALYNDGDGERKYLPQFFKFSVSNPLSVRTKVRTIKDITYLEACIENHTKSNLYMDQVDFEPAQQWKATRLEADEHPSAVKSEIGDLCKQPILIRAGGGIYNYLYQLRSSSDEAGQPKLELSSILGKFQITWRTNLGEPGRLQTQNIHSTPTANKDVDLRAVKVPPIIYAERPFMVNLCLTNQTDKTVGPFEVFVAPSMTGEERVVLVNGLQKLILPLVEAFESIKFDLSMVATQLGVQKISGITMYAVQEKKYYEPLPDIEIFVDAE
Length1776
PositionTail
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.07
Grand average of hydropathy-0.264
Instability index53.18
Isoelectric point6.01
Molecular weight192091.85
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22870
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.60|      21|      39|    1333|    1353|       3
---------------------------------------------------------------------------
 1333- 1353 (39.75/25.30)	RPSL.QPDPATLL..RFDPRDVFL
 1355- 1370 (22.34/10.03)	EDALtGPDPSAAA..DF......L
 1375- 1394 (31.52/18.08)	HP....PDPTATVpgEFTFRDRFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.08|      11|      39|    1036|    1047|       4
---------------------------------------------------------------------------
 1036- 1047 (16.49/12.36)	PIGKSvRIGSGN
 1077- 1087 (20.59/10.72)	PLPAS.QVGSSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.03|      11|      39|    1272|    1282|       5
---------------------------------------------------------------------------
 1272- 1282 (17.62/ 9.55)	SAAASARTSEQ
 1310- 1320 (19.41/11.34)	SPAAAAQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     189.38|      37|      39|     856|     892|       6
---------------------------------------------------------------------------
    6-   38 (35.91/11.48)	.........PPNPSP..VPvplpvPTPTPT..ANGTASSPKDQQQQ
  509-  533 (30.37/ 8.53)	............SSR..QP.....VVLHPI..FGSPTSFGGQPPMQ
  535-  569 (27.28/ 6.89)	VWSTRVNKSIPPTEDlkNP.qtyvPMPTTS..DERSSS........
  862-  898 (60.35/24.47)	GTSRNMVTSPTNSSP..SP.....SNNQGN..QGGATSAPGNSQMQ
  899-  931 (35.47/11.25)	EWVQGAIAKISNNSD..GA.....ATTTPNpmSGRSTFMP......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     152.48|      38|      40|    1141|    1180|       8
---------------------------------------------------------------------------
 1097- 1117 (25.19/ 8.42)	....................GNYTVLP.EVVEASLGPHMQNM
 1141- 1180 (69.60/44.07)	EWHrrNMFG..GPWSEPDDFGPLDNMPHQKVSGSINPHLSDM
 1183- 1222 (57.69/30.51)	DYG..NSLGvqSLWPRKRRLSERDAAFGLKTSVGLGGYLGVM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22870 with Med16 domain of Kingdom Viridiplantae
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