<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22867

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMAAAAAAERQLVVAVEGTAALGPYWSTIVGDYVEKIVRSFCAIEVPGQKLAGAPPELALVVFHTHGPYSAFGVQRSGWTKDIDAFLSWLSGISFSGGGFSEASTCEGLAEALTILQGSPNTTQSHQNHEAQKHCILVAASNPYPLPTPVYCIPTQSTDHKENTESSKEPSIADAEAVAKSFAQCSVSLSVISPKQLPTLKAIYNAGKRNPRAADPSVDHAKNPHFLVLLSENFMEARTALSRPLHGSLAPNQTVTKMDTAPAVTMAGPTSNANSSVNGPMMGRQPVGVGGVSTATVKLEPVTIPPMVSAPAFSHVTPISNVASQGISALQTSSPSLISQEANIANDNVQEHKPIIHPVQQPVRPGGHGSLLNNLSQVRLMNSTSLGGGATSMGLPNIGATPIQVHMSNMISSGMTSTPSVISSMSGPGQPISTQQMVQSTALGSFGSNTSTVSGNSNIAVSSSLPSIQSSMGMGQSVQPVAQGGLMAGSHLGQGGIAANQNVSGLGPTAISSVPAMMPTPGMAQSTGVNSLGATNNSAMNMPIGQHPNAQQPPPKYVKIWEGTLSGQRQGQPVFICKLEFHHCSAEKMFTIYGKALPRRCEAKDNALICILIFIDDGLGYKIGDANYVQ
Length629
PositionUnknown
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.05
Grand average of hydropathy-0.069
Instability index42.74
Isoelectric point7.01
Molecular weight65281.34
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22867
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     250.80|      46|      46|     398|     443|       1
---------------------------------------------------------------------------
  315-  368 (45.69/16.60)	.VTPI.....SNV.ASQGIsalqTSSPSLISQEANiandnvqEHKPIihPVQQPVRPGGHG
  398-  443 (87.16/37.76)	GATPIQVHM.SNM.ISSGM....TSTPSVISSMSG.......PGQPI..STQQMVQSTALG
  446-  487 (56.32/22.02)	GSNTSTVSGnSNIaVSS.......SLPSIQSSM.G.......MGQ....SVQPVAQGGLMA
  492-  529 (61.64/24.74)	GQGGI...A.ANQ.NVSGL......GPTAISSV.........PA.MM..PTPGMAQSTGVN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22867 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALSRPLHGSLAPNQTVTKMDTAPAVTMAGPTSNANSSVNGPMMGRQPVGVGGVSTAT
2) GMTSTPSVISSMSGPGQPISTQQMVQSTALGSFGSNTSTVSGNSNIAVS
3) LQTSSPSLISQEANIANDNVQEHKPIIHPVQQPVRPGGHGSLLNNL
239
413
329
295
461
374










Molecular Recognition Features






MoRF SequenceStartStop




1) KYVKIWE
555
561