<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22863

Description Mediator of RNA polymerase II transcription subunit 33A
SequenceMAMAMSAPPPASSSSPAWLEWAAEYTKAAQAESCPPPEWAARVAAAAAASAAGEGGDVPWSAGLAEVLARALLSGGGAPAAAAAAWKYAEAALAARLASPALLLALLSTRVIPQRFSRPMEYRLYLELLKRHGFSFHYQMKASNFRKIMDLIDGNLSLSKIFGISTCQPGVFVVHFVLCILWQLVDVVLDDEGLLELTPEKKAQWPTRPEDVSTFEGTFTEQRTEKIEKLQKMNTVTTMELIEHLLRNKVITRILSLARENMQSHWGAFTNRLHLLATNSSTLQNSAISLEPFQQLILGDCNVYGETKHNMRKRFHPIVASNPLSSPNGRCLGASYSALWIPIDMYLEDCLDGSIAATNSIKILSGLVKALQSVNRSTWHDAFLALWVASLRLVQREREPIEGPVPHLDTRLCMLLSITTLAVADIIEEADSLCNETELNSHTKEKKSIGNLRNELMLSLRMLGDYESLLVPPPCVVPAANQAATKAAMFISGISINNGYMENVNGMNYSGNMRHLIVESCISRNLLDTSAYYWPGYISNHANSVSLTLPSQLAGWSSFMKGAPLTQSLVNMLISTPAPSLAEVEKLFEVAVNGSDDDNVSAATVLCGATLLRGWNFQEHTVRLVVKLLSPSDPIDYSGRESQLIKLGPMLNVILSGISAVDYAPIFSFHGLIPELAAALMAICEVFGCLSPSVSWTLRTGEEISAHTVFSYAFILLLRLWKFNHPPLEYCVMGDGAPVGSQLTPEYLLLLRNSQVLSSSSLAKQRNGQRQLQVPTSHPSCEHPIFMDSFPKLKLWYRQHQACLASTLSGLAHGTPVRNNVDSLLNLMFRKANKGGTSIGSISGSSSISNSSGPGGDDLHLWPQLPAWEILEAVPFVVDAALTACSHGRLFPRELATGLKDLADFLPASLATIVSYFSAEVTRGVWKPASMNGSDWPSPSVNLSMVEEHIKKIVAATGVDVPRLVTGGSSSGTLPLPLAAFVSLTITYKLDKASERFLNLAGPALENLAASCPWPSMAIVAALWTQKVKRWSDFLVFSASRTVFHHNNDAVVQLLRSCFAATLGMSSTSVCGCGGVASLLGHGYCPGGFSPVAPGILYLRIFRCVKDCSILAEDILSLLMLSVKDIAETTVPRQRSDKLKKTKYGMRHGQVSLSAAMTQVKVAASLGATLVWLSGGTALVQSLIQEMLPSWFLSVQNLDQGGTSGGMVYKLGGHALAYLAVYSGMFAWGIDLTPVSRRRERVMRSHLEFLASALDGKISLGCDPSLWRAYVVGFLDLVVECTPCWVQEVELRVLKRLSSGLRQWGEDELAVALLRRAGSEAMGTAAELILGSEW
Length1334
PositionTail
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.08
Grand average of hydropathy0.139
Instability index41.76
Isoelectric point6.77
Molecular weight144777.50
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22863
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     289.34|      71|      73|     791|     863|       1
---------------------------------------------------------------------------
  718-  772 (92.05/55.10)	LRLWK...................FNHPP.LEYCVMG..DGAPVGSQLTPEYLLLLRN.............SQVLSSSSLAKQRNGQRQL
  793-  863 (121.12/82.98)	LKLWY...................RQHQACLASTLSGLAHGTPVRNNVDSLLNLMFRKANKGGTSIGSISGSSSISNSSGPGGDDLHLWP
  865-  940 (76.17/43.47)	LPAWEileavpfvvdaaltacshgRLFPRELATGLKDLADFLPA..SLATIVSYFSAEVTRGVWKPASMNGSDWPSPS............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     173.68|      53|     435|     542|     597|       2
---------------------------------------------------------------------------
  542-  597 (86.15/51.06)	ANSVSLTLPSQLAGWS.SFMKGA.PltqSLVNMLISTPAPSLAEVEKLFEVAVNGSDD
  979- 1033 (87.52/45.72)	AAFVSLTITYKLDKASeRFLNLAgP...ALENLAASCPWPSMAIVAALWTQKVKRWSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     195.41|      46|      46|     296|     341|       3
---------------------------------------------------------------------------
  259-  292 (44.46/22.05)	............RENMQSHWGAFTNRLHLLATNSSTLQNSAISLEP
  296-  341 (79.99/45.41)	LILGDCNVYGETKHNMRKRFHPIVASNPLSSPNGRCLGASYSALWI
  345-  388 (70.97/39.48)	MYLEDCLDGSIAATNSIKILSGLV..KALQSVNRSTWHDAFLALWV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.98|      18|      19|      21|      39|       4
---------------------------------------------------------------------------
   21-   39 (33.83/22.36)	WAAEYTKAAQAESCPPPeW
   43-   60 (30.15/15.25)	VAAAAAASAAGEGGDVP.W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.66|      44|     532|     134|     178|       5
---------------------------------------------------------------------------
  134-  178 (75.76/56.06)	FSFHYQMK..ASNFRKIMDLIdGNLSLSKIFGISTCQP....GVFVVHFVL
  667-  716 (69.90/46.48)	FSFHGLIPelAAALMAICEVF.GCLSPSVSWTLRTGEEisahTVFSYAFIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.50|      13|     528|      67|     100|       6
---------------------------------------------------------------------------
   62-   74 (21.66/13.62)	AGLA.EVLARALLS
   95-  108 (16.84/16.02)	ARLAsPALLLALLS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22863 with Med33 domain of Kingdom Viridiplantae
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