<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22860

Description Pre-mRNA-processing protein 40A
SequenceMASNMQPSGPPQPPRPPMMGSSAQPQNLGPPMPMQFRPVVPSQQPPQFMPPAAQQFRPVGQPMPGANIGMPGQMPHFPQPGQHLSHSSQVPPASQGVPMAYQPARPMSSAPMQPQQQAAYPGGHLPTMGAPMQPPSYTYQPTSIPPAVQPWGTAPGQSVPHVTPLVQPGHQPVPVTATLPSVNSSEPSSSDWQEHTAAEGKKYYYNKKTRQSSWEKPIELMTPLERADASTEWKEFTTPEGRKYYFNKVTKQSKWSIPDELKAARELAEKASNQQSDRETGTNAASEHSTIPANQSSTAVGLIAPSTHDASANSVPPGAGTSHNVDNTSSSSTVGKQNGGPNTAAVPVTTSTEVQLVATDAGTIRNNNENSSVTTAADTEDGTSAEDLEEAKKTMPVAGKINVTPLEEKTSEEEPVVYATKAEAKNAFKSLLESVNVESDWTWDQTMRVIINDKRYGALKTLGERKQAFNEYLNQRKKFEAEEKRIKQRKARDDFLAMLEECKELTSSTRWSKAILMFEDDERFKAVERPREREDLFENYLVELHKKEKAKAVEEHRRHLAEYKAFLESCDFIKATTQWRKVQERLEDDERCSRLEKIDRLNIFQEYIRHLEKEEEEQKRVQKEQVRRQERKNRDVFRKMLEEHVTDGTITAKTRWRDYCSQIKDSQAYLAVASNTSGSTPKELFDDVIEELDKQYLDDKTRVKEVVKSGKIPMTTSWTLEEFQTAILDDDALKGISTINIKLIYDDQIERLKEKEQKDAKKRQRLGENFSDLLYSITEISASSTWDDSKQLFEDSQEFRALDSETYARELFEECVVHLKERLKEKERLREEEKAKREREREEREKKKEKERKEKERKEKDREKDREKEKGKDRARRDEMDIDGADVENHGSKDKKRDKEKKHKRRHHDTDDVSSERDDKDDTKKSRRHSSDRKKSRKGSVSTIIDTVISE
Length951
PositionUnknown
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.06
Grand average of hydropathy-1.123
Instability index53.58
Isoelectric point6.40
Molecular weight108494.73
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22860
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     133.36|      17|      17|      22|      38|       1
---------------------------------------------------------------------------
    6-   16 (21.56/ 6.40)	..QPS.....GPPQ..PP..RP
   22-   38 (36.80/15.26)	SAQPQ...NLGPPM..PMQFRP
   42-   58 (30.64/11.68)	SQQPP...QFMPPA..AQQFRP
   59-   75 (21.08/ 6.12)	VGQPMpgaNIG..M..PGQM.P
  118-  134 (23.27/ 7.39)	AAYPG...GHLPTMgaPMQ..P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     156.62|      28|      28|     820|     847|       2
---------------------------------------------------------------------------
  522-  550 (27.08/10.00)	.ERFKAVERPREREDLFENYLVEL.hkKEKA
  820-  847 (46.02/22.04)	KERLKEKERLREEEKAKREREREE...REKK
  850-  867 (24.33/ 8.25)	KER.KEKER.KEKD...REKDRE........
  868-  896 (33.30/13.95)	KE..KGKDRARRDEMDIDGADVENhgsKDKK
  904-  928 (25.89/ 9.24)	KRRHHDTDDVSSERDDKDDTKKSR...R...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     234.12|      40|      40|     191|     230|       3
---------------------------------------------------------------------------
  149-  185 (52.43/32.93)	..QPWGTAPGQSVPHVTPL...VQPG.HQPVPVTATLPSVN.SS
  191-  230 (71.96/48.47)	DWQEHTAAEGKKYYYNKKT...RQSSWEKPIELMTPLERAD.AS
  232-  272 (62.80/41.18)	EWKEFTTPEGRKYYFNKVT...KQSKWSIPDELKAARELAEkAS
  273-  311 (46.93/28.55)	N.QQSDRETGTNAASEHSTipaNQSS..TAVGLIAP.STHD.AS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     217.57|      35|      66|     487|     521|       4
---------------------------------------------------------------------------
  423-  453 (38.27/21.49)	...EAKNA.........FKSLLESV....NVESDWTWDQTMRVIIND
  487-  521 (56.24/35.07)	KQRKARDD.........FLAMLEEC...KELTSSTRWSKAILMFEDD
  555-  589 (52.26/32.06)	EHRRHLAE.........YKAFLESC...DFIKATTQWRKVQERLEDD
  629-  656 (29.45/14.82)	QERKNRDV.........FRKMLEEHvtdGTITAKTRW..........
  753-  796 (41.35/23.81)	KEKEQKDAkkrqrlgenFSDLLYSI...TEISASSTWDDSKQLFEDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     127.71|      24|      26|     337|     360|       6
---------------------------------------------------------------------------
  313-  329 (23.14/10.10)	.NSVPPGAG....TSHNVD...NTS
  337-  360 (39.69/22.60)	QNGGPNTAAVPVTTSTEVQLV.ATD
  366-  378 (18.57/ 6.64)	NNN....ENSSVTT........AAD
  379-  400 (27.46/13.36)	TEDG..TSAEDLEEAKKTMPV.AGK
  401-  420 (18.86/ 6.86)	INVTP....LEEKTSEEEPVVyAT.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22860 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ERLREEEKAKREREREEREKKKEKERKEKERKEKDREKDREKEKGKDRARRDEMDIDGADVENHGSKDKKRDKEKKHKRRHHDTDDVSSERDDKDDTKKSRRHSSDRKKSRKGSVSTIIDTVISE
2) MASNMQPSGPPQPPRPPMMGSSAQPQNLGPPMPMQFRPVVPSQQPPQFMPPAAQQFRPVGQPMPGANIGMPGQMPHFPQPGQHLSHSSQVPPASQGVPMAYQPARPMSSAPMQPQQQAAYPGGHLPTMGAPMQPPSYTYQPTSIPPAVQPWGTAPGQSVPHVTPLVQPGHQPVPVTATLPSVNSSEPSSSDWQEHTAAEGKKYYYN
3) WSIPDELKAARELAEKASNQQSDRETGTNAASEHSTIPANQSSTAVGLIAPSTHDASANSVPPGAGTSHNVDNTSSSSTVGKQNGGPNTAAVPVTTSTEVQLVATDAGTIRNNNENSSVTTAADTEDGTSAEDLEEAKKTMPVAGKINVTPLEEKTSEEEPVVYA
827
1
255
951
206
419










Molecular Recognition Features






MoRF SequenceStartStop




1) GRKYYFNK
2) KKHKRRHHD
241
901
248
909