<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22859

Description Putative mediator of RNA polymerase II transcription subunit 26b
SequenceMADGLDRWRDFFRGAGAGICDVIENAILVAAADAPRELLHRRDRIAERLFTAHRRDAAPPSLGSAAASATPATPVEEDKGSVRRVAEKESKVDSSSNGAHGGGHGHGDEEDDSDSDSDDERLRRAAASNYGHSYDDDDDDDQEEEDEQQHAADDAQEEEEDHEAEELEALTNEIDEESQIVGEVLRIKDLLLHKEDHSDATLFESLRRLQLMQLSVSTLKATEIGRAVKRLRKHNSQKICHLVRTLIEGWKVLVDEWVSTTSVALADNSPDSSNPSVVDEEDEEGLPSPPLDEGAFFATQPTSIQLSEFFDEMDEDGNLRHNSDASLGNKRGNNGGRPANYSAVASQEPPRHSPGAIEKVRFRRPESVRQEPSMRQANPQKPQSSSLQVKPHGALNSNKQSKPSSYESGPGRPLKAAPPQKPFGDMKPRQTHNSVERRPTTSQMDKSRLAAQSSSGARLELAKPKVNDDGLDNNRKLEAAKRKLQERYQEAENAKRQRTIQVMELGDIPKPKHQNRQPMVKSRNNLRNWANGRR
Length534
PositionUnknown
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.04
Grand average of hydropathy-1.069
Instability index62.58
Isoelectric point5.34
Molecular weight59305.17
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22859
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.80|      20|      21|     132|     151|       1
---------------------------------------------------------------------------
  104-  126 (25.71/10.16)	HGHGDEEDDsDSDSDDERlrRAA
  132-  151 (36.51/17.37)	HSYDDDDDD.DQEEEDEQ..QHA
  153-  169 (20.58/ 6.73)	...DDAQEE.EEDHEAEE..LEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     131.66|      36|      39|     365|     403|       2
---------------------------------------------------------------------------
  347-  373 (34.74/20.05)	......QEPPRHS....P.GAIEKVRFRRpESVRQEPS
  374-  411 (55.89/37.51)	MRQANPQKPQSSSlQVKPHGALNSNKQSKpSSYESGPG
  414-  440 (41.02/19.57)	LKAAPPQKPFG...DMKPRQT........hNSVERRPT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.73|      11|      21|     458|     468|       3
---------------------------------------------------------------------------
  458-  468 (19.83/11.92)	RLELAKPKVND
  476-  486 (16.91/ 9.17)	KLEAAKRKLQE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22859 with Med26 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RLFTAHRRDAAPPSLGSAAASATPATPVEEDKGSVRRVAEKESKVDSSSNGAHGGGHGHGDEEDDSDSDSDDERLRRAAASNYGHSYDDDDDDDQEEEDEQQHAADDAQEEEEDHEAEELEALTNEID
2) SEFFDEMDEDGNLRHNSDASLGNKRGNNGGRPANYSAVASQEPPRHSPGAIEKVRFRRPESVRQEPSMRQANPQKPQSSSLQVKPHGALNSNKQSKPSSYESGPGRPLKAAPPQKPFGDMKPRQTHNSVERRPTTSQMDKSRLAAQSSSGARLELAKPKVNDDGLDNNRKLEAAKRKLQERYQEAENAKRQRTIQVMELGDIPKPKHQNRQPMVKSRNNLRNWANGRR
3) VALADNSPDSSNPSVVDEEDEEGLPSPPLDEGAFFA
48
307
263
175
534
298










Molecular Recognition Features






MoRF SequenceStartStop




1) DDERLRRAAASNYGHSYD
2) GAIEKVRFRR
3) RKLEA
4) RLELAKPKV
118
355
475
458
135
364
479
466