<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22839

Description U-box domain-containing protein 35-like
SequenceMATQEEAVVPESSPSSDPPITIGLAVSSSKSSKYAVKWALKNFSARERTRFMLIHVRQKVTLVPTPMGNYVPVDQVRDDIASAYEKEVECEAQNMLLMYKNMCNGKVEAEILVVKGDDVAETISGVVSACQMHKLVVGVSSQGNFMRKSKGTRTSSRICKSIPSFCMVYAVSKGGLSMVYSPGSEGDNSYEIFQVNESSNSELYSDDKSSVSEKSPTVSRALQELMRSEDKANTPCASDQISGSSSLPITDKATTDKVNFEREKLKIKLGHMRGVCKLVEDESTSASQQMIDLIEKHAQEEARLVEVHSRINTAIEAARKEREQRYAAEAQARHVRDLANEEALKKQHVQLTASREADDMQKLEKLLELGGKPYILFTWEEMESATSSFSEALKIGSGANGTVYKGKIHQTAVAIKLLKSDNSRVTKHFKQELEVLSKTRHRHLLLLLGACLDRACLVYVYMENGSLEDRLQCKGGTSPLPWYYCFRIAWEIALALIYLHSSRPKPIIHRDLKPANILLDSNFTSKIGDAGIATLLPLSEASSTHTIRKHTDLVGTLFYMDPEYQRSGQVSAKSDVYALGMVFLQLLTAKSPMGLADTVERAVEERRLVDILDQRAGKWPVKAAYELAQLGLSCLEMRGKNRPDLKSNVLVVLERLNKIASTTRDSVRPVPTAPPSHFICPILKRVMQDPCIASDGYSYERVAIEMWLHENDVSPLTKTQLPDKNLVPNHALLCAINSWKGEAGTGGITG
Length750
PositionTail
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.06
Grand average of hydropathy-0.312
Instability index39.03
Isoelectric point8.03
Molecular weight83094.26
Publications
PubMed=30683860

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22839
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     183.36|      59|     211|      42|     109|       1
---------------------------------------------------------------------------
   42-  109 (84.94/77.24)	NFsARERTRFMLIHVRQKVTLVPTPMGNyvPVDQVRDDIasayEKEVECEAQnmLLMYKNMCNGKVEA
  259-  317 (98.42/61.22)	NF.EREKLKIKLGHMRGVCKLVEDESTS..ASQQMIDLI....EKHAQEEAR..LVEVHSRINTAIEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     213.18|      48|     211|     484|     531|       2
---------------------------------------------------------------------------
  484-  531 (83.12/61.88)	YCF.RIAWEIA.LALIYLHSSRPKPIIHR.DLKPANILLDSNFTSKIGDAG
  619-  663 (57.24/40.15)	WPV.KAAYELAqLGLSCLE.MRGK...NRpDLK.SNVLVVLERLNKIASTT
  697-  744 (72.82/53.24)	YSYeRVAIEMW.LHENDVSPLTKTQLPDK.NLVPNHALL.CAINSWKGEAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.23|      21|     221|       1|      21|       3
---------------------------------------------------------------------------
    1-   21 (38.27/25.05)	MATQEEAVVP....ESSPSSDPPIT
  226-  250 (31.96/19.67)	MRSEDKANTPcasdQISGSSSLPIT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22839 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LYSDDKSSVSEKSPTVSRALQELMRSEDKANTPCASDQISGSSSLPITDKATT
203
255










Molecular Recognition Features






MoRF SequenceStartStop




NANANA