<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP22827

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMDGGHGLRQPMSPAISASAVVPQQRQMQLHHHPARPAIVDLFTLYLSMNSTQRAEDPSRESSNKLQKRVTALNRDLPPRDEQFISDYEQLRMQFPDQEQLQAVTESVLISFVLQCSSHAPQSEFLLFATRCLCARGHLRWDSLLPSLLNAVSSMEAPVGQGVPVTSGGPVTPSSSAITMPNAPNFHPSNPASPLSVMNTIGSPTQSGIDQPVGANVSPIKAAEFSSSAQLGTAARGDQSRRGAEISYLHHLSCRILLAGLESNLKPATHAVIFQHMVNWLVNWDQRPHNMDEADAMPTWRLEKTLHEWMHLCLDVIWILVNEEKCRIPFYELVRCNLQFLGNIPDDEALVSIIMEIHRRRDMVCMHMQMLDQHLHCPTFATHRFLSQSYPSIAGESVTNLRYSPITYPSVLGEPLHGEDLANSIPKGGLDWERALRCLRHALRTTPSPDWWRRVLLVAPCYRSQSQQSSTPGAVFSPDMIGEAVADRTIEFLRLTNSETHCWQDWLLFADIFFFLMKSGCIDFLDFVDKLASRVTNSDQQILRSNHVTWLLAQIIRIEIVMNTLSSDPRKVETTRKIISFHKEDKSLDANNIGPQSILLDFISSSQTLRIWSFNTSIREHLNSDQLQKGKQIDEWWRQMTKASGERMIDFTNLDERATGMFWVLSFTMAQPACEAVMNWFTSAGMADLIQGPNMQPNERIMMMRETYPLSMSLLSGLSINLCLKLAFQLEETIFLGQAVPSIAMVETYVRLLLITPHSLFRPHFTTLTQRSPSILSKSGVSLLLLEILNYRLLPLYRYHGKSKALMYDVTKIISMIKGKRGEHRLFRLAENLCMNLILSLKDFFFVKKELKGPTEFTETLNRITIISLAITIKTRGIAEVEHMIYLQPLLEQIMATSQHTWSEKTLRYFPPLIRDFLMGRMDKRGQAIQAWQQAETTVINQCNQLLSPSAEPNYVMTYLSHSFPQHRQYLCAGAWMLMNGHLEINSANLARVLREFSPEEVTANIYTMVDVLLHHIQFEVQRGHLAQDLLSKAITNLSFFIWTHELLPLDILLLALIDRDDDPYALRIVISLLEKPELQQRVKAFCSSRSPEHWLKNQHPKRVELQKALGNHLSWKDRYPPFFDDIAARLLPVIPLIIYRLIENDATDIADRVLAFYSSLLAFHPLRFTFVRDILAYFYGHLPIKLIGRILNLLGVSTKTPFSESFAKYLVSSNSSVCPPPEYFANLLLNLVNNVIPPLSSKSKSNPADTTRSTFNKHHASSQPGGIGNNDGQRAFYQNQDPGSYTQLVLETAVIEILSLPVSAAQIVSSLVQIIAHVQAMLRQSNSGQGMSGGLGQSSVLTTSPSGGGAEPAGSNQANSAASGINAINFVSRSGYSSQQLSVLMIQACGLLLAQLPPEFHMQLYSEAARVIKDCWWLADSSRPVKELDSAVGYALLDPTWASQDNTSTAIGNIVALLHSFFSNLPQEWLESTHTVIKHLRPVNSVAMLRIAFRILGPLLPRLAFARPLFMKTLALLFNVLGDVFGKNSQVPNPVEASEITDIIDFLYHAVMYEGQGGPVQSTSKPKLEILTLCGKVIEILRPDVQHLLAHLKTDPNCSIYAATHPKLVQNTS
Length1613
PositionTail
OrganismPanicum miliaceum (Proso millet) (Broomcorn millet)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Panicodae> Paniceae> Panicinae> Panicum.
Aromaticity0.08
Grand average of hydropathy-0.079
Instability index47.58
Isoelectric point6.93
Molecular weight181253.71
Publications
PubMed=30683860

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP22827
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.96|      17|      17|    1204|    1220|       1
---------------------------------------------------------------------------
 1204- 1220 (31.40/18.00)	ESFAKYLVSSNSSVCPP
 1222- 1238 (30.56/17.34)	EYFANLLLNLVNNVIPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.02|      16|      20|     389|     404|       2
---------------------------------------------------------------------------
  389-  404 (30.67/19.10)	YPSIAGESV..TNLRYS.P
  407-  425 (21.36/10.99)	YPSVLGEPLhgEDLANSiP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      67.02|      19|      19|    1149|    1167|       3
---------------------------------------------------------------------------
 1133- 1155 (21.76/ 9.98)	VI.PLIIYRLIEndatdIADRVLA
 1156- 1176 (24.70/12.33)	FYSSLLAFHPLR..ftfVRD.ILA
 1178- 1191 (20.56/ 9.02)	FYGHL....PIK.....LIGRIL.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     202.42|      64|     636|      32|     103|       4
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   32-  103 (99.78/92.65)	HPARPAIVDLFTlylSMNSTQRAEDPSRESSNKLQkrvtaLNRDLPPRDEQFISDYE...QLRMQFPDQEQL...QAV
  670-  739 (102.65/74.61)	QPACEAVMNWFT...SAGMADLIQGPNMQPNERIM.....MMRETYPLSMSLLSGLSinlCLKLAFQLEETIflgQAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.40|      34|     328|    1076|    1115|       6
---------------------------------------------------------------------------
 1076- 1115 (58.13/55.73)	PELQ.......QRVKAFCSsrspehWLKNQHPKRVELQKALGNHL...SW
 1398- 1441 (53.27/36.19)	PEFHmqlyseaARVIKDCW......WLADSSRPVKELDSAVGYALldpTW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.05|      37|     328|     512|     550|       8
---------------------------------------------------------------------------
  512-  548 (63.37/48.80)	FFFLMKS..GCIDFLDFVDKLAS...RVTNSDQQILRSNHVT
  843-  884 (51.69/34.07)	FFFVKKElkGPTEFTETLNRITIislAITIKTRGIAEVEHMI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.39|      10|      20|     885|     894|       9
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  885-  894 (18.02/10.18)	YLQPLLEQIM
  908-  917 (19.37/11.57)	YFPPLIRDFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.64|      28|     182|    1260|    1316|      14
---------------------------------------------------------------------------
 1271- 1298 (48.54/71.90)	DGQRAFYQNQDPGSYTQLVLETAVIEIL
 1554- 1581 (48.11/14.66)	EGQGGPVQSTSKPKLEILTLCGKVIEIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.79|      12|      21|     437|     448|      18
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  437-  448 (22.41/12.91)	CLRHALRTTPSP
  460-  471 (22.37/12.87)	CYRSQSQQSSTP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP22827 with Med23 domain of Kingdom Viridiplantae
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